azacitidine-3348 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the azacitidine-3348 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADM adrenomedullin
AGRP agouti related neuropeptide
AHNAK AHNAK nucleoprotein
AIM1L absent in melanoma 1-like
ALDOB aldolase B, fructose-bisphosphate
AMOTL2 angiomotin like 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA1 annexin A1
APOB apolipoprotein B
ARHGAP4 Rho GTPase activating protein 4
ARMC4 armadillo repeat containing 4
ATF3 activating transcription factor 3
BLZF1 basic leucine zipper nuclear factor 1
BMP6 bone morphogenetic protein 6
C14ORF1 chromosome 14 open reading frame 1
C8ORF4 chromosome 8 open reading frame 4
CCKBR cholecystokinin B receptor
CD84 CD84 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CES3 carboxylesterase 3
CFP complement factor properdin
CLSTN2 calsyntenin 2
CNN1 calponin 1, basic, smooth muscle
COL14A1 collagen, type XIV, alpha 1
CREB5 cAMP responsive element binding protein 5
CYR61 cysteine-rich, angiogenic inducer, 61
DCT dopachrome tautomerase
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS12 dehydrogenase/reductase (SDR family) member 12
DLX2 distal-less homeobox 2
DNALI1 dynein, axonemal, light intermediate chain 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ERCC2 excision repair cross-complementation group 2
ERN1 endoplasmic reticulum to nucleus signaling 1
FLNC filamin C, gamma
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO5 flavin containing monooxygenase 5
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GJA4 gap junction protein, alpha 4, 37kDa
GPR87 G protein-coupled receptor 87
GSTTP1 glutathione S-transferase theta pseudogene 1
GYPB glycophorin B (MNS blood group)
HBEGF heparin-binding EGF-like growth factor
HYAL3 hyaluronoglucosaminidase 3
IFI44 interferon-induced protein 44
IKZF4 IKAROS family zinc finger 4 (Eos)
IL12RB1 interleukin 12 receptor, beta 1
IL6 interleukin 6
INHBE inhibin, beta E
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
LOXL2 lysyl oxidase-like 2
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MC5R melanocortin 5 receptor
MED25 mediator complex subunit 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLAT plasminogen activator, tissue
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PROL1 proline rich, lacrimal 1
RPL10L ribosomal protein L10-like
RPS2 ribosomal protein S2
SAMD9 sterile alpha motif domain containing 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMR3A submaxillary gland androgen regulated protein 3A
SOCS3 suppressor of cytokine signaling 3
SPEF1 sperm flagellar 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPX spexin hormone
STRA6 stimulated by retinoic acid 6
STYK1 serine/threonine/tyrosine kinase 1
T T, brachyury homolog (mouse)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAT tyrosine aminotransferase
TGFB2 transforming growth factor, beta 2
TLR1 toll-like receptor 1
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TREM2 triggering receptor expressed on myeloid cells 2
TXNIP thioredoxin interacting protein
USP36 ubiquitin specific peptidase 36
VEGFA vascular endothelial growth factor A
XYLB xylulokinase homolog (H. influenzae)
ZNF286A zinc finger protein 286A
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABT1 activator of basal transcription 1
ADGRA3 adhesion G protein-coupled receptor A3
ADORA2B adenosine A2b receptor
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKIRIN1 akirin 1
ANKRD36B ankyrin repeat domain 36B
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
AXIN1 axin 1
B3GNT1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CBX4 chromobox homolog 4
CCNE1 cyclin E1
CCNL2 cyclin L2
CDCA4 cell division cycle associated 4
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN3 claudin 3
CLDND1 claudin domain containing 1
CLK2 CDC-like kinase 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COA7 cytochrome c oxidase assembly factor 7 (putative)
CUL1 cullin 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DOLK dolichol kinase
E2F6 E2F transcription factor 6
EFNA4 ephrin-A4
EXO1 exonuclease 1
FAM102A family with sequence similarity 102, member A
FAM172A family with sequence similarity 172, member A
FAM57A family with sequence similarity 57, member A
FKSG49 FKSG49
FOXK2 forkhead box K2
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GEMIN6 gem (nuclear organelle) associated protein 6
GLCE glucuronic acid epimerase
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR19 G protein-coupled receptor 19
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INHBB inhibin, beta B
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KRI1 KRI1 homolog (S. cerevisiae)
MFSD5 major facilitator superfamily domain containing 5
MOCS3 molybdenum cofactor synthesis 3
MOGS mannosyl-oligosaccharide glucosidase
MYLIP myosin regulatory light chain interacting protein
NPY1R neuropeptide Y receptor Y1
NXF1 nuclear RNA export factor 1
NXT1 nuclear transport factor 2-like export factor 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PEX11B peroxisomal biogenesis factor 11 beta
PEX2 peroxisomal biogenesis factor 2
PHACTR4 phosphatase and actin regulator 4
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POGK pogo transposable element with KRAB domain
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POU2F1 POU class 2 homeobox 1
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PUS1 pseudouridylate synthase 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RBM38 RNA binding motif protein 38
RGS16 regulator of G-protein signaling 16
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RPP25 ribonuclease P/MRP 25kDa subunit
RUFY2 RUN and FYVE domain containing 2
RWDD2A RWD domain containing 2A
SGPP1 sphingosine-1-phosphate phosphatase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SNORA21 small nucleolar RNA, H/ACA box 21
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2
STBD1 starch binding domain 1
THAP11 THAP domain containing 11
TMEM115 transmembrane protein 115
TULP4 tubby like protein 4
UNKL unkempt family zinc finger-like
USP21 ubiquitin specific peptidase 21
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZFHX3 zinc finger homeobox 3
ZMAT3 zinc finger, matrin-type 3
ZNF253 zinc finger protein 253
ZNF675 zinc finger protein 675
ZNF83 zinc finger protein 83