azacitidine-4010 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the azacitidine-4010 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOE apolipoprotein E
ARHGAP28 Rho GTPase activating protein 28
ARL14 ADP-ribosylation factor-like 14
ATF3 activating transcription factor 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBC3 BCL2 binding component 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP2 bone morphogenetic protein 2
C14ORF1 chromosome 14 open reading frame 1
C1ORF54 chromosome 1 open reading frame 54
C8A complement component 8, alpha polypeptide
C8ORF4 chromosome 8 open reading frame 4
CCR2 chemokine (C-C motif) receptor 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN1 claudin 1
COL6A2 collagen, type VI, alpha 2
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYSLTR1 cysteinyl leukotriene receptor 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DST dystonin
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EGR1 early growth response 1
FBXO22 F-box protein 22
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXL1 forkhead box L1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GCGR glucagon receptor
GYPB glycophorin B (MNS blood group)
HAS2 hyaluronan synthase 2
HIST1H2AG histone cluster 1, H2ag
HPSE2 heparanase 2 (inactive)
IL11 interleukin 11
IL13 interleukin 13
IL18R1 interleukin 18 receptor 1
IL24 interleukin 24
IL32 interleukin 32
IL33R interleukin 33 receptor
IL6 interleukin 6
ITGA7 integrin, alpha 7
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KRT34 keratin 34, type I
LOC1720 dihydrofolate reductase pseudogene
MILR1 mast cell immunoglobulin-like receptor 1
MMP10 matrix metallopeptidase 10
NF1 neurofibromin 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRG1 neuregulin 1
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PALM paralemmin
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLN phospholamban
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RGS16 regulator of G-protein signaling 16
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
RPL10L ribosomal protein L10-like
SAT1 spermidine/spermine N1-acetyltransferase 1
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SGSM3 small G protein signaling modulator 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMAD4 SMAD family member 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STAT2 signal transducer and activator of transcription 2, 113kDa
STC2 stanniocalcin 2
TEX14 testis expressed 14
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
XYLB xylulokinase homolog (H. influenzae)
YIPF2 Yip1 domain family, member 2

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ADGRA3 adhesion G protein-coupled receptor A3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHDC1 AT hook, DNA binding motif, containing 1
ARHGAP12 Rho GTPase activating protein 12
ASTE1 asteroid homolog 1 (Drosophila)
BAG4 BCL2-associated athanogene 4
C11ORF30 chromosome 11 open reading frame 30
C1ORF106 chromosome 1 open reading frame 106
CCDC94 coiled-coil domain containing 94
CDCA4 cell division cycle associated 4
CDCA8 cell division cycle associated 8
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLK2 CDC-like kinase 2
CLP1 cleavage and polyadenylation factor I subunit 1
DBR1 debranching RNA lariats 1
DCAF13 DDB1 and CUL4 associated factor 13
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
E2F6 E2F transcription factor 6
EIF5A2 eukaryotic translation initiation factor 5A2
EN1 engrailed homeobox 1
FADD Fas (TNFRSF6)-associated via death domain
FAM172A family with sequence similarity 172, member A
FAM69A family with sequence similarity 69, member A
FGFBP1 fibroblast growth factor binding protein 1
FZD2 frizzled class receptor 2
FZD8 frizzled class receptor 8
GAREM GRB2 associated, regulator of MAPK1
GBX2 gastrulation brain homeobox 2
GEMIN6 gem (nuclear organelle) associated protein 6
GFOD1 glucose-fructose oxidoreductase domain containing 1
GJC1 gap junction protein, gamma 1, 45kDa
GLI3 GLI family zinc finger 3
GPR1 G protein-coupled receptor 1
GRAMD1B GRAM domain containing 1B
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HHEX hematopoietically expressed homeobox
HILPDA hypoxia inducible lipid droplet-associated
HJURP Holliday junction recognition protein
HMGA2 high mobility group AT-hook 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
IP6K2 inositol hexakisphosphate kinase 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KDM4D lysine (K)-specific demethylase 4D
KIAA0753 KIAA0753
KIAA0922 KIAA0922
LHFPL2 lipoma HMGIC fusion partner-like 2
LMNB1 lamin B1
LOC100272216 uncharacterized LOC100272216
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MFSD5 major facilitator superfamily domain containing 5
MSL1 male-specific lethal 1 homolog (Drosophila)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXT1 nuclear transport factor 2-like export factor 1
ORC1 origin recognition complex, subunit 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCGF1 polycomb group ring finger 1
PEX11B peroxisomal biogenesis factor 11 beta
PMP22 peripheral myelin protein 22
PPARG peroxisome proliferator-activated receptor gamma
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RNF25 ring finger protein 25
RNF4 ring finger protein 4
RPP14 ribonuclease P/MRP 14kDa subunit
S100PBP S100P binding protein
SALL2 spalt-like transcription factor 2
SIAH2 siah E3 ubiquitin protein ligase 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2
STBD1 starch binding domain 1
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBC1D12 TBC1 domain family, member 12
TMEM115 transmembrane protein 115
TMEM177 transmembrane protein 177
TMEM223 transmembrane protein 223
TUBD1 tubulin, delta 1
URGCP upregulator of cell proliferation
USP21 ubiquitin specific peptidase 21
VANGL1 VANGL planar cell polarity protein 1
VGLL4 vestigial-like family member 4
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR37 WD repeat domain 37
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBED8 zinc finger, BED-type containing 8
ZBTB44 zinc finger and BTB domain containing 44
ZC3H3 zinc finger CCCH-type containing 3
ZFHX4 zinc finger homeobox 4
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF248 zinc finger protein 248
ZNF273 zinc finger protein 273
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZSCAN26 zinc finger and SCAN domain containing 26