azacyclonol-1937 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the azacyclonol-1937 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ANGPTL4 angiopoietin-like 4
ARC activity-regulated cytoskeleton-associated protein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BIK BCL2-interacting killer (apoptosis-inducing)
BRD2 bromodomain containing 2
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIZ1 CDKN1A interacting zinc finger protein 1
CRELD2 cysteine-rich with EGF-like domains 2
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYB561 cytochrome b561
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELL2 elongation factor, RNA polymerase II, 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FOXO3 forkhead box O3
GADD45B growth arrest and DNA-damage-inducible, beta
GK glycerol kinase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2BC histone cluster 1, H2bc
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOXD1 homeobox D1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL24 interleukin 24
IL33R interleukin 33 receptor
IL6 interleukin 6
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
JUN jun proto-oncogene
JUND jun D proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KRT86 keratin 86, type II
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MANF mesencephalic astrocyte-derived neurotrophic factor
MT1X metallothionein 1X
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
OASL 2'-5'-oligoadenylate synthetase-like
OVGP1 oviductal glycoprotein 1, 120kDa
PDGFA platelet-derived growth factor alpha polypeptide
PECR peroxisomal trans-2-enoyl-CoA reductase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCD protein kinase C, delta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SQLE squalene epoxidase
SQSTM1 sequestosome 1
STK10 serine/threonine kinase 10
STOM stomatin
SUGP1 SURP and G patch domain containing 1
TMEM50B transmembrane protein 50B
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB3 tribbles pseudokinase 3
UPP1 uridine phosphorylase 1
WASL Wiskott-Aldrich syndrome-like
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP36 ZFP36 ring finger protein
ZNF165 zinc finger protein 165
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
AKTIP AKT interacting protein
ANAPC1 anaphase promoting complex subunit 1
ANXA2P3 annexin A2 pseudogene 3
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARMT1 acidic residue methyltransferase 1
B3GNT1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL7C B-cell CLL/lymphoma 7C
C5ORF28 chromosome 5 open reading frame 28
C5ORF30 chromosome 5 open reading frame 30
C8ORF60 chromosome 8 open reading frame 60
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CD2AP CD2-associated protein
CD53 CD53 molecule
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP70 centrosomal protein 70kDa
CEP85 centrosomal protein 85kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHUK conserved helix-loop-helix ubiquitous kinase
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPOX coproporphyrinogen oxidase
CROT carnitine O-octanoyltransferase
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DCK deoxycytidine kinase
DCP2 decapping mRNA 2
DENND1B DENN/MADD domain containing 1B
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
E2F8 E2F transcription factor 8
ECT2 epithelial cell transforming 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EMD emerin
EPM2AIP1 EPM2A (laforin) interacting protein 1
EXOC5 exocyst complex component 5
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FAM188A family with sequence similarity 188, member A
GNG10 guanine nucleotide binding protein (G protein), gamma 10
HSPB8 heat shock 22kDa protein 8
KCTD3 potassium channel tetramerization domain containing 3
KIAA0753 KIAA0753
LHFP lipoma HMGIC fusion partner
LYPD1 LY6/PLAUR domain containing 1
LYRM2 LYR motif containing 2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MCOLN1 mucolipin 1
METTL18 methyltransferase like 18
MRPS15 mitochondrial ribosomal protein S15
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO19 myosin XIX
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAP1L2 nucleosome assembly protein 1-like 2
NCSTN nicastrin
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUPL2 nucleoporin like 2
OARD1 O-acyl-ADP-ribose deacylase 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCNA proliferating cell nuclear antigen
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYGB phosphorylase, glycogen; brain
RANBP6 RAN binding protein 6
RNF167 ring finger protein 167
RPAP3 RNA polymerase II associated protein 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS10P5 ribosomal protein S10 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUVBL2 RuvB-like AAA ATPase 2
RWDD3 RWD domain containing 3
SAP30L SAP30-like
SDHAF3 succinate dehydrogenase complex assembly factor 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SHCBP1 SHC SH2-domain binding protein 1
SLMO2 slowmo homolog 2 (Drosophila)
SNX17 sorting nexin 17
SPDL1 spindle apparatus coiled-coil protein 1
THYN1 thymocyte nuclear protein 1
TMEM177 transmembrane protein 177
TOP2B topoisomerase (DNA) II beta 180kDa
TRIM5 tripartite motif containing 5
UBA2 ubiquitin-like modifier activating enzyme 2
UBA3 ubiquitin-like modifier activating enzyme 3
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF217 zinc finger protein 217
ZNF32 zinc finger protein 32
ZNF430 zinc finger protein 430
ZNF665 zinc finger protein 665