azacyclonol-2020 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the azacyclonol-2020 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOB aldolase B, fructose-bisphosphate
ANKRD12 ankyrin repeat domain 12
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BIRC7 baculoviral IAP repeat containing 7
BMP2K BMP2 inducible kinase
C7ORF43 chromosome 7 open reading frame 43
CACFD1 calcium channel flower domain containing 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALB2 calbindin 2
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CHPF chondroitin polymerizing factor
CKB creatine kinase, brain
CLTA clathrin, light chain A
CNTFR ciliary neurotrophic factor receptor
COMT catechol-O-methyltransferase
CPM carboxypeptidase M
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DNAH7 dynein, axonemal, heavy chain 7
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSPP dentin sialophosphoprotein
DUSP26 dual specificity phosphatase 26 (putative)
EFR3B EFR3 homolog B (S. cerevisiae)
ELN elastin
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FADS3 fatty acid desaturase 3
FBRS fibrosin
FGFR2 fibroblast growth factor receptor 2
FOXP3 forkhead box P3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL1 guanine nucleotide binding protein-like 1
GPX3 glutathione peroxidase 3
GTPBP1 GTP binding protein 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAMP hepcidin antimicrobial peptide
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGHA1 immunoglobulin heavy constant alpha 1
IHH indian hedgehog
INSR insulin receptor
IQCC IQ motif containing C
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMS2 LIM and senescent cell antigen-like domains 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MBP myelin basic protein
MED27 mediator complex subunit 27
MFSD11 major facilitator superfamily domain containing 11
MIIP migration and invasion inhibitory protein
MOB3B MOB kinase activator 3B
MT3 metallothionein 3
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYF6 myogenic factor 6 (herculin)
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NCR2 natural cytotoxicity triggering receptor 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPEPL1 aminopeptidase-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OMG oligodendrocyte myelin glycoprotein
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PADI1 peptidyl arginine deiminase, type I
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PLK3 polo-like kinase 3
POMT2 protein-O-mannosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
RAB2A RAB2A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SFRP1 secreted frizzled-related protein 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SORBS3 sorbin and SH3 domain containing 3
SPDEF SAM pointed domain containing ETS transcription factor
STAB2 stabilin 2
TMCC2 transmembrane and coiled-coil domain family 2
TRIM29 tripartite motif containing 29
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX2 zinc finger homeobox 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACACA acetyl-CoA carboxylase alpha
ADAM15 ADAM metallopeptidase domain 15
ASAP1-IT1 ASAP1 intronic transcript 1
ASTE1 asteroid homolog 1 (Drosophila)
BCL7C B-cell CLL/lymphoma 7C
BIN2 bridging integrator 2
BST1 bone marrow stromal cell antigen 1
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CCNL2 cyclin L2
CCNT1 cyclin T1
CD320 CD320 molecule
CDK5 cyclin-dependent kinase 5
CLDN15 claudin 15
COG4 component of oligomeric golgi complex 4
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COQ9 coenzyme Q9
CRYBG3 beta-gamma crystallin domain containing 3
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DBF4B DBF4 zinc finger B
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPF2 D4, zinc and double PHD fingers family 2
EMC9 ER membrane protein complex subunit 9
ERCC2 excision repair cross-complementation group 2
FADS2 fatty acid desaturase 2
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GALNS galactosamine (N-acetyl)-6-sulfatase
GBAP1 glucosidase, beta, acid pseudogene 1
GLB1L2 galactosidase, beta 1-like 2
GMEB1 glucocorticoid modulatory element binding protein 1
GOLGA3 golgin A3
GPHN gephyrin
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HMGB3P1 high mobility group box 3 pseudogene 1
IFITM3 interferon induced transmembrane protein 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
JMJD4 jumonji domain containing 4
KIFC1 kinesin family member C1
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
MAGEF1 melanoma antigen family F1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIS18BP1 MIS18 binding protein 1
MON1B MON1 secretory trafficking family member B
MPC1 mitochondrial pyruvate carrier 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MT1HL1 metallothionein 1H-like 1
MYLIP myosin regulatory light chain interacting protein
MYO9A myosin IXA
NADSYN1 NAD synthetase 1
NAGK N-acetylglucosamine kinase
NCAPH non-SMC condensin I complex, subunit H
NDE1 nudE neurodevelopment protein 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCTP phosphatidylcholine transfer protein
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKN1 protein kinase N1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB4B RAB4B, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUVBL2 RuvB-like AAA ATPase 2
SAC3D1 SAC3 domain containing 1
SAP30L SAP30-like
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX6 sorting nexin 6
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA13 stimulated by retinoic acid 13
STYXL1 serine/threonine/tyrosine interacting-like 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TRAPPC12 trafficking protein particle complex 12
TRMT61B tRNA methyltransferase 61B
TSSC4 tumor suppressing subtransferable candidate 4
UBE2M ubiquitin-conjugating enzyme E2M
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VILL villin-like
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WDR41 WD repeat domain 41
WDR6 WD repeat domain 6
YIPF1 Yip1 domain family, member 1
ZDHHC4 zinc finger, DHHC-type containing 4