azacyclonol-5398 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the azacyclonol-5398 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
APAF1 apoptotic peptidase activating factor 1
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
ATXN2L ataxin 2-like
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BHLHE40 basic helix-loop-helix family, member e40
C11ORF63 chromosome 11 open reading frame 63
CASP4 caspase 4, apoptosis-related cysteine peptidase
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP164 centrosomal protein 164kDa
CFAP45 cilia and flagella associated protein 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN7 chloride channel, voltage-sensitive 7
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
CRMP1 collapsin response mediator protein 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEFB126 defensin, beta 126
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ECE1 endothelin converting enzyme 1
EDNRB endothelin receptor type B
EGR1 early growth response 1
EPHB2 EPH receptor B2
FSCN1 fascin actin-bundling protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GLS glutaminase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GRM8 glutamate receptor, metabotropic 8
GSTP1 glutathione S-transferase pi 1
HBS1L HBS1-like translational GTPase
HDAC7 histone deacetylase 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HYAL3 hyaluronoglucosaminidase 3
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICA1 islet cell autoantigen 1, 69kDa
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
IL1RAP interleukin 1 receptor accessory protein
IL24 interleukin 24
INHBE inhibin, beta E
ITM2C integral membrane protein 2C
JUN jun proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA1324 KIAA1324
LIMK2 LIM domain kinase 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAST3 microtubule associated serine/threonine kinase 3
MEF2D myocyte enhancer factor 2D
MKL1 megakaryoblastic leukemia (translocation) 1
MT1F metallothionein 1F
MYOZ1 myozenin 1
NDP Norrie disease (pseudoglioma)
NOD2 nucleotide-binding oligomerization domain containing 2
NOVA2 neuro-oncological ventral antigen 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRXN1 neurexin 1
NUP88 nucleoporin 88kDa
NXPH4 neurexophilin 4
OASL 2'-5'-oligoadenylate synthetase-like
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCSK6 proprotein convertase subtilisin/kexin type 6
PICK1 protein interacting with PRKCA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLAU plasminogen activator, urokinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PTPRJ protein tyrosine phosphatase, receptor type, J
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGCC regulator of cell cycle
RNF186 ring finger protein 186
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLMO1 slowmo homolog 1 (Drosophila)
SMYD2 SET and MYND domain containing 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPTB spectrin, beta, erythrocytic
SSX3 synovial sarcoma, X breakpoint 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBL2 transducin (beta)-like 2
TCP10 t-complex 10
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
USP19 ubiquitin specific peptidase 19
ZNF471 zinc finger protein 471
ZNF532 zinc finger protein 532

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
ARMC4 armadillo repeat containing 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C4ORF29 chromosome 4 open reading frame 29
C9ORF9 chromosome 9 open reading frame 9
CA11 carbonic anhydrase XI
CAMK1 calcium/calmodulin-dependent protein kinase I
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
CLSPN claspin
COPZ2 coatomer protein complex, subunit zeta 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXORF56 chromosome X open reading frame 56
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGAT1 diacylglycerol O-acyltransferase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM46C family with sequence similarity 46, member C
FCHO1 FCH domain only 1
FSD1 fibronectin type III and SPRY domain containing 1
GAS2 growth arrest-specific 2
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1D histone cluster 1, H1d
HIST1H2AL histone cluster 1, H2al
HOXC11 homeobox C11
HOXC5 homeobox C5
IFI27 interferon, alpha-inducible protein 27
IGFBP6 insulin-like growth factor binding protein 6
IPO8 importin 8
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
KLK5 kallikrein-related peptidase 5
LOC390998 ribosomal protein L10 pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
LYPD1 LY6/PLAUR domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MCOLN1 mucolipin 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVP major vault protein
NFE2L3 nuclear factor, erythroid 2-like 3
NKX3-2 NK3 homeobox 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA9 protocadherin alpha 9
PDE12 phosphodiesterase 12
PGR progesterone receptor
PKD2 polycystic kidney disease 2 (autosomal dominant)
PODXL2 podocalyxin-like 2
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP2 RNA polymerase II associated protein 2
S100A9 S100 calcium binding protein A9
SCAI suppressor of cancer cell invasion
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIRAL2 SIR2 antiphage like 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLIT2 slit homolog 2 (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3 stromal antigen 3
STX5 syntaxin 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TCTN1 tectonic family member 1
TGFB3 transforming growth factor, beta 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNRC6B trinucleotide repeat containing 6B
VASH2 vasohibin 2
XAB2 XPA binding protein 2
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC13 zinc finger, DHHC-type containing 13
ZFP69B ZFP69 zinc finger protein B
ZMYM3 zinc finger, MYM-type 3
ZNF136 zinc finger protein 136
ZNF16 zinc finger protein 16
ZNF552 zinc finger protein 552
ZNF623 zinc finger protein 623
ZNF639 zinc finger protein 639
ZNF74 zinc finger protein 74