azaperone-3573 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the azaperone-3573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AKR1C4 aldo-keto reductase family 1, member C4
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANO2 anoctamin 2, calcium activated chloride channel
APOC4 apolipoprotein C-IV
APOM apolipoprotein M
BCL2 B-cell CLL/lymphoma 2
C10ORF95 chromosome 10 open reading frame 95
C2 complement component 2
C7ORF69 chromosome 7 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CARD10 caspase recruitment domain family, member 10
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CCDC85B coiled-coil domain containing 85B
CCR9 chemokine (C-C motif) receptor 9
CHAT choline O-acetyltransferase
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN10 claudin 10
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRAT carnitine O-acetyltransferase
CT62 cancer/testis antigen 62
CTSZ cathepsin Z
CUL7 cullin 7
CXORF21 chromosome X open reading frame 21
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCN decorin
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMX1 empty spiracles homeobox 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
FAM131A family with sequence similarity 131, member A
FBLN1 fibulin 1
FZD9 frizzled class receptor 9
GAL3ST4 galactose-3-O-sulfotransferase 4
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GRM6 glutamate receptor, metabotropic 6
HES2 hes family bHLH transcription factor 2
HFE hemochromatosis
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGA1 high mobility group AT-hook 1
IFNW1 interferon, omega 1
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRT19P2 keratin 19 pseudogene 2
KRT31 keratin 31, type I
LHX2 LIM homeobox 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAN2A2 mannosidase, alpha, class 2A, member 2
MID1 midline 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTMR7 myotubularin related protein 7
MTSS1 metastasis suppressor 1
NABP1 nucleic acid binding protein 1
NFIB nuclear factor I/B
NR2E3 nuclear receptor subfamily 2, group E, member 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PLXNC1 plexin C1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTCRA pre T-cell antigen receptor alpha
RIMS3 regulating synaptic membrane exocytosis 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNX3 runt-related transcription factor 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDC2 syndecan 2
SDC3 syndecan 3
SETBP1 SET binding protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SNRK SNF related kinase
SUGP1 SURP and G patch domain containing 1
SYCE1L synaptonemal complex central element protein 1-like
TBC1D2 TBC1 domain family, member 2
TK2 thymidine kinase 2, mitochondrial
TREX1 three prime repair exonuclease 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
UHRF1BP1L UHRF1 binding protein 1-like
USP2 ubiquitin specific peptidase 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VGF VGF nerve growth factor inducible
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASCC2 activating signal cointegrator 1 complex subunit 2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAHCC1 BAH domain and coiled-coil containing 1
C9ORF3 chromosome 9 open reading frame 3
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC9 coiled-coil domain containing 9
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CFAP45 cilia and flagella associated protein 45
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO1A coronin, actin binding protein, 1A
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DGKE diacylglycerol kinase, epsilon 64kDa
DNMBP dynamin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGLN2 egl-9 family hypoxia-inducible factor 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM204A family with sequence similarity 204, member A
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
GCHFR GTP cyclohydrolase I feedback regulator
GINS3 GINS complex subunit 3 (Psf3 homolog)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1E histone cluster 1, H1e
HIST1H2AL histone cluster 1, H2al
HIST1H2BI histone cluster 1, H2bi
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC10 homeobox C10
IFT81 intraflagellar transport 81
IMPACT impact RWD domain protein
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5C lysine (K)-specific demethylase 5C
KIAA1107 KIAA1107
KLF2 Kruppel-like factor 2
LINC00597 long intergenic non-protein coding RNA 597
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
NBEAL2 neurobeachin-like 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OLFML2A olfactomedin-like 2A
PARP16 poly (ADP-ribose) polymerase family, member 16
PDLIM2 PDZ and LIM domain 2 (mystique)
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PTDSS2 phosphatidylserine synthase 2
PTPRU protein tyrosine phosphatase, receptor type, U
PYCRL pyrroline-5-carboxylate reductase-like
REEP4 receptor accessory protein 4
RNF31 ring finger protein 31
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
S100A4 S100 calcium binding protein A4
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SIDT1 SID1 transmembrane family, member 1
SIX1 SIX homeobox 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
STON1 stonin 1
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TESC tescalcin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM121 transmembrane protein 121
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR76 WD repeat domain 76
ZBTB44 zinc finger and BTB domain containing 44
ZC3H3 zinc finger CCCH-type containing 3
ZNF16 zinc finger protein 16
ZNF286A zinc finger protein 286A
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A
ZSCAN26 zinc finger and SCAN domain containing 26