azaperone-5877 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the azaperone-5877 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
ADAM23 ADAM metallopeptidase domain 23
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIM1L absent in melanoma 1-like
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOB aldolase B, fructose-bisphosphate
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMC9 armadillo repeat containing 9
C17ORF53 chromosome 17 open reading frame 53
C1QB complement component 1, q subcomponent, B chain
CABIN1 calcineurin binding protein 1
CAMKMT calmodulin-lysine N-methyltransferase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD58 CD58 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DENND3 DENN/MADD domain containing 3
DLC1 DLC1 Rho GTPase activating protein
DMBT1 deleted in malignant brain tumors 1
EGR1 early growth response 1
ELMO2 engulfment and cell motility 2
EPHA5 EPH receptor A5
EXPH5 exophilin 5
FAIM2 Fas apoptotic inhibitory molecule 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FER fer (fps/fes related) tyrosine kinase
FLT4 fms-related tyrosine kinase 4
GRIA3 glutamate receptor, ionotropic, AMPA 3
HIST1H1T histone cluster 1, H1t
HIST1H4A histone cluster 1, H4a
HRASLS2 HRAS-like suppressor 2
HRK harakiri, BCL2 interacting protein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFI6 interferon, alpha-inducible protein 6
IRF4 interferon regulatory factor 4
ISYNA1 inositol-3-phosphate synthase 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KHK ketohexokinase (fructokinase)
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT17 keratin 17, type I
KYNU kynureninase
LIPG lipase, endothelial
MAPT microtubule-associated protein tau
METTL7A methyltransferase like 7A
MORC1 MORC family CW-type zinc finger 1
MTMR12 myotubularin related protein 12
MX1 MX dynamin-like GTPase 1
MYRF myelin regulatory factor
NCKIPSD NCK interacting protein with SH3 domain
NEK9 NIMA-related kinase 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOL10 nucleolar protein 10
NT5M 5',3'-nucleotidase, mitochondrial
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OSBP2 oxysterol binding protein 2
PACRG PARK2 co-regulated
PASK PAS domain containing serine/threonine kinase
PAX8 paired box 8
PDE10A phosphodiesterase 10A
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD3 phospholipase D family, member 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PROL1 proline rich, lacrimal 1
RAB2A RAB2A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RAD52 RAD52 homolog (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
SC5D sterol-C5-desaturase
SCIN scinderin
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SIRPB1 signal-regulatory protein beta 1
SLC25A30 solute carrier family 25, member 30
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNW1 SNW domain containing 1
SQLE squalene epoxidase
SULF1 sulfatase 1
TCP11L1 t-complex 11, testis-specific-like 1
TK2 thymidine kinase 2, mitochondrial
TM2D1 TM2 domain containing 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UNC13A unc-13 homolog A (C. elegans)
UROD uroporphyrinogen decarboxylase
ZNF280B zinc finger protein 280B
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
APOL6 apolipoprotein L, 6
ATP13A2 ATPase type 13A2
BAK1 BCL2-antagonist/killer 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
C5 complement component 5
CAPN15 calpain 15
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNL2 cyclin L2
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CENPQ centromere protein Q
CEP131 centrosomal protein 131kDa
CLDN14 claudin 14
CLDN15 claudin 15
CLDN4 claudin 4
CNPY3 canopy FGF signaling regulator 3
CTSK cathepsin K
CTSO cathepsin O
DEAF1 DEAF1 transcription factor
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNMBP dynamin binding protein
DOCK1 dedicator of cytokinesis 1
EHD3 EH-domain containing 3
EMC6 ER membrane protein complex subunit 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM102A family with sequence similarity 102, member A
FAM50B family with sequence similarity 50, member B
FPGS folylpolyglutamate synthase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GPR1 G protein-coupled receptor 1
GSR glutathione reductase
HIST1H1E histone cluster 1, H1e
HOOK1 hook microtubule-tethering protein 1
HS1BP3 HCLS1 binding protein 3
IL4R interleukin 4 receptor
IL6 interleukin 6
JUNB jun B proto-oncogene
KLHL26 kelch-like family member 26
KRT4 keratin 4, type II
KRT75 keratin 75, type II
LHFPL2 lipoma HMGIC fusion partner-like 2
LOC730101 uncharacterized LOC730101
LRRC15 leucine rich repeat containing 15
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MCRS1 microspherule protein 1
METRN meteorin, glial cell differentiation regulator
MFSD11 major facilitator superfamily domain containing 11
MYLK myosin light chain kinase
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NUBP2 nucleotide binding protein 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
ORAI3 ORAI calcium release-activated calcium modulator 3
PALMD palmdelphin
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POM121 POM121 transmembrane nucleoporin
PTGFR prostaglandin F receptor (FP)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RANGAP1 Ran GTPase activating protein 1
RNF122 ring finger protein 122
RNF25 ring finger protein 25
RPAP1 RNA polymerase II associated protein 1
RPS17P5 ribosomal protein S17 pseudogene 5
S100A14 S100 calcium binding protein A14
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SOD3 superoxide dismutase 3, extracellular
TBL3 transducin (beta)-like 3
TMEM104 transmembrane protein 104
TMEM156 transmembrane protein 156
TNS2 tensin 2
TRAIP TRAF interacting protein
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TTBK2 tau tubulin kinase 2
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNKL unkempt family zinc finger-like
USP20 ubiquitin specific peptidase 20
WDR18 WD repeat domain 18
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF276 zinc finger protein 276
ZNF34 zinc finger protein 34