azaperone-6151 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the azaperone-6151 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
BCL2L1 BCL2-like 1
C17ORF53 chromosome 17 open reading frame 53
CD22 CD22 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDCP1 CUB domain containing protein 1
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEP250 centrosomal protein 250kDa
CFAP74 cilia and flagella associated protein 74
CLCA2 chloride channel accessory 2
CLCN1 chloride channel, voltage-sensitive 1
CLDN17 claudin 17
CRTC1 CREB regulated transcription coactivator 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP4 dual specificity phosphatase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EREG epiregulin
ESR1 estrogen receptor 1
FAIM2 Fas apoptotic inhibitory molecule 2
FASLG Fas ligand (TNF superfamily, member 6)
FBXO31 F-box protein 31
FGFR1 fibroblast growth factor receptor 1
FST follistatin
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1
GFRA1 GDNF family receptor alpha 1
GK2 glycerol kinase 2
GPR137 G protein-coupled receptor 137
GSPT1 G1 to S phase transition 1
HAB1 B1 for mucin
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-DOA major histocompatibility complex, class II, DO alpha
HUS1 HUS1 checkpoint homolog (S. pombe)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KAT8 K(lysine) acetyltransferase 8
KIF1C kinesin family member 1C
KLK7 kallikrein-related peptidase 7
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT24 keratin 24, type I
LECT1 leukocyte cell derived chemotaxin 1
LMF1 lipase maturation factor 1
MAGEA8 melanoma antigen family A8
MCAM melanoma cell adhesion molecule
MED31 mediator complex subunit 31
MGC2889 uncharacterized protein MGC2889
MYL10 myosin, light chain 10, regulatory
NF2 neurofibromin 2 (merlin)
NLRP1 NLR family, pyrin domain containing 1
NUP188 nucleoporin 188kDa
OPTN optineurin
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PBX1 pre-B-cell leukemia homeobox 1
PDGFA platelet-derived growth factor alpha polypeptide
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCH1 phospholipase C, eta 1
PRKCA protein kinase C, alpha
PRR5L proline rich 5 like
PVR poliovirus receptor
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
REC8 REC8 meiotic recombination protein
ROM1 retinal outer segment membrane protein 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RSG1 REM2 and RAB-like small GTPase 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A10 solute carrier family 30, member 10
SOCS7 suppressor of cytokine signaling 7
SP1 Sp1 transcription factor
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPPL2B signal peptide peptidase like 2B
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAGLN3 transgelin 3
TIMELESS timeless circadian clock
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSKS testis-specific serine kinase substrate
TSPAN4 tetraspanin 4
USP29 ubiquitin specific peptidase 29
WBP5 WW domain binding protein 5
WDR55 WD repeat domain 55
XIST X inactive specific transcript (non-protein coding)
YLPM1 YLP motif containing 1
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOX2 acyl-CoA oxidase 2, branched chain
AOAH acyloxyacyl hydrolase (neutrophil)
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOL6 apolipoprotein L, 6
ATG10 autophagy related 10
BBS1 Bardet-Biedl syndrome 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BSPRY B-box and SPRY domain containing
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CBR3 carbonyl reductase 3
CCDC9 coiled-coil domain containing 9
CCL20 chemokine (C-C motif) ligand 20
CDR2L cerebellar degeneration-related protein 2-like
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRABP2 cellular retinoic acid binding protein 2
CRMP1 collapsin response mediator protein 1
CRY2 cryptochrome circadian clock 2
CTSD cathepsin D
CTSV cathepsin V
CXORF56 chromosome X open reading frame 56
DFNA5 deafness, autosomal dominant 5
DGKE diacylglycerol kinase, epsilon 64kDa
DUSP8 dual specificity phosphatase 8
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EMILIN2 elastin microfibril interfacer 2
ENO2 enolase 2 (gamma, neuronal)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM127B family with sequence similarity 127, member B
FAM63A family with sequence similarity 63, member A
FAM86C1 family with sequence similarity 86, member C1
FKBP14 FK506 binding protein 14, 22 kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPR20 G protein-coupled receptor 20
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2BN histone cluster 1, H2bn
HIST1H4A histone cluster 1, H4a
HOXA5 homeobox A5
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL24 interleukin 24
INF2 inverted formin, FH2 and WH2 domain containing
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA1024 KIAA1024
KIF17 kinesin family member 17
KLF2 Kruppel-like factor 2
LOC100287590 uncharacterized LOC100287590
LOC390998 ribosomal protein L10 pseudogene
LTC4S leukotriene C4 synthase
LYPLA2P1 lysophospholipase II pseudogene 1
MAGEF1 melanoma antigen family F1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MTMR12 myotubularin related protein 12
MVP major vault protein
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NARFL nuclear prelamin A recognition factor-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NPIPB15 nuclear pore complex interacting protein family, member B15
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYOX1 prenylcysteine oxidase 1
PDE12 phosphodiesterase 12
PGBD5 piggyBac transposable element derived 5
PGP phosphoglycolate phosphatase
PITX2 paired-like homeodomain 2
PWAR5 Prader Willi/Angelman region RNA 5
RASAL1 RAS protein activator like 1 (GAP1 like)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SGCE sarcoglycan, epsilon
SIRT6 sirtuin 6
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNX16 sorting nexin 16
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TEX15 testis expressed 15
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TTLL1 tubulin tyrosine ligase-like family member 1
UPB1 ureidopropionase, beta
USP32 ubiquitin specific peptidase 32
WDR60 WD repeat domain 60
ZC2HC1A zinc finger, C2HC-type containing 1A
ZFP37 ZFP37 zinc finger protein
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675