| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the azapropazone-3143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADRB3 | adrenoceptor beta 3 |
| AFF4 | AF4/FMR2 family, member 4 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOC4 | apolipoprotein C-IV |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BMP7 | bone morphogenetic protein 7 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALD1 | caldesmon 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD8B | CD8b molecule |
| CLEC1B | C-type lectin domain family 1, member B |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| COPE | coatomer protein complex, subunit epsilon |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRAT | carnitine O-acetyltransferase |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| EFNA5 | ephrin-A5 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EN1 | engrailed homeobox 1 |
| ENDOD1 | endonuclease domain containing 1 |
| ENG | endoglin |
| EPHB4 | EPH receptor B4 |
| ESR1 | estrogen receptor 1 |
| EXOSC2 | exosome component 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FN1 | fibronectin 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GAS8 | growth arrest-specific 8 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MID1 | midline 1 |
| MSH4 | mutS homolog 4 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OCM2 | oncomodulin 2 |
| OLFML2A | olfactomedin-like 2A |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PEG10 | paternally expressed 10 |
| POU2F2 | POU class 2 homeobox 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRSS53 | protease, serine, 53 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB26 | RAB26, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| RARA | retinoic acid receptor, alpha |
| RGS14 | regulator of G-protein signaling 14 |
| RGS5 | regulator of G-protein signaling 5 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRR | serine racemase |
| SSTR5 | somatostatin receptor 5 |
| TFDP3 | transcription factor Dp family, member 3 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP64 | ZFP64 zinc finger protein |
| ZFR2 | zinc finger RNA binding protein 2 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADORA3 | adenosine A3 receptor |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| CAPN15 | calpain 15 |
| CD180 | CD180 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPB | centromere protein B, 80kDa |
| CENPO | centromere protein O |
| CEP170B | centrosomal protein 170B |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLEC3B | C-type lectin domain family 3, member B |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CUL9 | cullin 9 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNMBP | dynamin binding protein |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FKBPL | FK506 binding protein like |
| FPGS | folylpolyglutamate synthase |
| FZD6 | frizzled class receptor 6 |
| GALE | UDP-galactose-4-epimerase |
| GCH1 | GTP cyclohydrolase 1 |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GLCE | glucuronic acid epimerase |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPATCH2L | G patch domain containing 2-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0355 | KIAA0355 |
| KIAA1107 | KIAA1107 |
| KLRAP1 | killer cell lectin-like receptor subfamily A pseudogene 1 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MB | myoglobin |
| MED9 | mediator complex subunit 9 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MVP | major vault protein |
| NABP1 | nucleic acid binding protein 1 |
| NBEA | neurobeachin |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PLCD1 | phospholipase C, delta 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POR | P450 (cytochrome) oxidoreductase |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRDM1 | PR domain containing 1, with ZNF domain |
| QSER1 | glutamine and serine rich 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RND1 | Rho family GTPase 1 |
| SALL2 | spalt-like transcription factor 2 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| ST5 | suppression of tumorigenicity 5 |
| STBD1 | starch binding domain 1 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM180 | transmembrane protein 180 |
| TMEM184C | transmembrane protein 184C |
| TONSL | tonsoku-like, DNA repair protein |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPYL2 | TSPY-like 2 |
| TUBA3D | tubulin, alpha 3d |
| TUFT1 | tuftelin 1 |
| UBTD1 | ubiquitin domain containing 1 |
| UCN | urocortin |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XAB2 | XPA binding protein 2 |
| YOD1 | YOD1 deubiquitinase |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF280B | zinc finger protein 280B |
| ZNF528 | zinc finger protein 528 |