azathioprine-1945 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the azathioprine-1945 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACSL4 acyl-CoA synthetase long-chain family member 4
ADCK2 aarF domain containing kinase 2
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AGTPBP1 ATP/GTP binding protein 1
AKAP12 A kinase (PRKA) anchor protein 12
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATF6B activating transcription factor 6 beta
ATXN7L3B ataxin 7-like 3B
C16ORF45 chromosome 16 open reading frame 45
CDC40 cell division cycle 40
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIZ1 CDKN1A interacting zinc finger protein 1
CLDN15 claudin 15
COPS7B COP9 signalosome subunit 7B
CPE carboxypeptidase E
CPOX coproporphyrinogen oxidase
CUL4A cullin 4A
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EID1 EP300 interacting inhibitor of differentiation 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPS8L1 EPS8-like 1
FAM149B1 family with sequence similarity 149, member B1
FAM188A family with sequence similarity 188, member A
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GOSR2 golgi SNAP receptor complex member 2
GRM4 glutamate receptor, metabotropic 4
H2AFY2 H2A histone family, member Y2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2AE histone cluster 1, H2ae
HOXA10 homeobox A10
HRH3 histamine receptor H3
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
INPP5K inositol polyphosphate-5-phosphatase K
ITM2B integral membrane protein 2B
KLHL24 kelch-like family member 24
KNOP1 lysine-rich nucleolar protein 1
KRIT1 KRIT1, ankyrin repeat containing
KRT86 keratin 86, type II
LARP1 La ribonucleoprotein domain family, member 1
LGALS8 lectin, galactoside-binding, soluble, 8
LITAF lipopolysaccharide-induced TNF factor
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MPDZ multiple PDZ domain protein
MTF2 metal response element binding transcription factor 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
N4BP2L2 NEDD4 binding protein 2-like 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NPAS2 neuronal PAS domain protein 2
NUP205 nucleoporin 205kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PITPNA phosphatidylinositol transfer protein, alpha
PLCD1 phospholipase C, delta 1
PLCE1 phospholipase C, epsilon 1
PNPLA4 patatin-like phospholipase domain containing 4
PODXL podocalyxin-like
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAI14 retinoic acid induced 14
RANBP3 RAN binding protein 3
RAP1B RAP1B, member of RAS oncogene family
RIOK3 RIO kinase 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF167 ring finger protein 167
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RWDD3 RWD domain containing 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT6 sirtuin 6
SLC25A44 solute carrier family 25, member 44
SLC38A7 solute carrier family 38, member 7
SNX24 sorting nexin 24
SNX4 sorting nexin 4
SPAG9 sperm associated antigen 9
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SURF2 surfeit 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPT1 tumor protein, translationally-controlled 1
U2SURP U2 snRNP-associated SURP domain containing
UBB ubiquitin B
URI1 URI1, prefoldin-like chaperone
USP24 ubiquitin specific peptidase 24
WWTR1 WW domain containing transcription regulator 1
YIPF6 Yip1 domain family, member 6
ZNF337 zinc finger protein 337
ZNF354A zinc finger protein 354A
ZNF652 zinc finger protein 652
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ALDOC aldolase C, fructose-bisphosphate
APOO apolipoprotein O
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC7 armadillo repeat containing 7
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAK1 BCL2-antagonist/killer 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C17ORF70 chromosome 17 open reading frame 70
C17ORF85 chromosome 17 open reading frame 85
CCDC130 coiled-coil domain containing 130
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD53 CD53 molecule
CENPM centromere protein M
CEP97 centrosomal protein 97kDa
CIDEC cell death-inducing DFFA-like effector c
CNTD2 cyclin N-terminal domain containing 2
DDA1 DET1 and DDB1 associated 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPDC1 DEP domain containing 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNM1 dynamin 1
DOCK1 dedicator of cytokinesis 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ESM1 endothelial cell-specific molecule 1
FAM102A family with sequence similarity 102, member A
FAM134C family with sequence similarity 134, member C
FAM175B family with sequence similarity 175, member B
FGF4 fibroblast growth factor 4
FGFBP1 fibroblast growth factor binding protein 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FMO4 flavin containing monooxygenase 4
FPGS folylpolyglutamate synthase
FZD4 frizzled class receptor 4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GOLGA8B golgin A8 family, member B
GPX2 glutathione peroxidase 2
IL24 interleukin 24
KCTD20 potassium channel tetramerization domain containing 20
KIF20B kinesin family member 20B
KLC2 kinesin light chain 2
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
KRT75 keratin 75, type II
LUC7L LUC7-like (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MED22 mediator complex subunit 22
MID1IP1 MID1 interacting protein 1
MOXD1 monooxygenase, DBH-like 1
MVP major vault protein
NABP2 nucleic acid binding protein 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NRGN neurogranin (protein kinase C substrate, RC3)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OCEL1 occludin/ELL domain containing 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALM paralemmin
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPRM protein tyrosine phosphatase, receptor type, M
PYCARD PYD and CARD domain containing
RBMS3 RNA binding motif, single stranded interacting protein 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS19 regulator of G-protein signaling 19
RNF130 ring finger protein 130
SAP30L SAP30-like
SERTAD3 SERTA domain containing 3
SETD1B SET domain containing 1B
SHPK sedoheptulokinase
SIPA1 signal-induced proliferation-associated 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SPX spexin hormone
STEAP3 STEAP family member 3, metalloreductase
STK25 serine/threonine kinase 25
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM260 transmembrane protein 260
TSPAN32 tetraspanin 32
TTC26 tetratricopeptide repeat domain 26
TTC31 tetratricopeptide repeat domain 31
UBE2O ubiquitin-conjugating enzyme E2O
UBXN2B UBX domain protein 2B
UCKL1 uridine-cytidine kinase 1-like 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC24 zinc finger, DHHC-type containing 24
ZMYM3 zinc finger, MYM-type 3
ZNF552 zinc finger protein 552