| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the azathioprine-1945 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADCK2 | aarF domain containing kinase 2 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ATF6B | activating transcription factor 6 beta |
| ATXN7L3B | ataxin 7-like 3B |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CDC40 | cell division cycle 40 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLDN15 | claudin 15 |
| COPS7B | COP9 signalosome subunit 7B |
| CPE | carboxypeptidase E |
| CPOX | coproporphyrinogen oxidase |
| CUL4A | cullin 4A |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EPS8L1 | EPS8-like 1 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM188A | family with sequence similarity 188, member A |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| H2AFY2 | H2A histone family, member Y2 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H2AE | histone cluster 1, H2ae |
| HOXA10 | homeobox A10 |
| HRH3 | histamine receptor H3 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| ITM2B | integral membrane protein 2B |
| KLHL24 | kelch-like family member 24 |
| KNOP1 | lysine-rich nucleolar protein 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LARP1 | La ribonucleoprotein domain family, member 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LITAF | lipopolysaccharide-induced TNF factor |
| MECP2 | methyl CpG binding protein 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MPDZ | multiple PDZ domain protein |
| MTF2 | metal response element binding transcription factor 2 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NPAS2 | neuronal PAS domain protein 2 |
| NUP205 | nucleoporin 205kDa |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PITPNA | phosphatidylinositol transfer protein, alpha |
| PLCD1 | phospholipase C, delta 1 |
| PLCE1 | phospholipase C, epsilon 1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PODXL | podocalyxin-like |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAI14 | retinoic acid induced 14 |
| RANBP3 | RAN binding protein 3 |
| RAP1B | RAP1B, member of RAS oncogene family |
| RIOK3 | RIO kinase 3 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RNF167 | ring finger protein 167 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RWDD3 | RWD domain containing 3 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SIRT6 | sirtuin 6 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC38A7 | solute carrier family 38, member 7 |
| SNX24 | sorting nexin 24 |
| SNX4 | sorting nexin 4 |
| SPAG9 | sperm associated antigen 9 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SURF2 | surfeit 2 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPT1 | tumor protein, translationally-controlled 1 |
| U2SURP | U2 snRNP-associated SURP domain containing |
| UBB | ubiquitin B |
| URI1 | URI1, prefoldin-like chaperone |
| USP24 | ubiquitin specific peptidase 24 |
| WWTR1 | WW domain containing transcription regulator 1 |
| YIPF6 | Yip1 domain family, member 6 |
| ZNF337 | zinc finger protein 337 |
| ZNF354A | zinc finger protein 354A |
| ZNF652 | zinc finger protein 652 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACVR2B | activin A receptor, type IIB |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ALDOC | aldolase C, fructose-bisphosphate |
| APOO | apolipoprotein O |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC7 | armadillo repeat containing 7 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| CCDC130 | coiled-coil domain containing 130 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD53 | CD53 molecule |
| CENPM | centromere protein M |
| CEP97 | centrosomal protein 97kDa |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNTD2 | cyclin N-terminal domain containing 2 |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEPDC1 | DEP domain containing 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DNM1 | dynamin 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ESM1 | endothelial cell-specific molecule 1 |
| FAM102A | family with sequence similarity 102, member A |
| FAM134C | family with sequence similarity 134, member C |
| FAM175B | family with sequence similarity 175, member B |
| FGF4 | fibroblast growth factor 4 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FPGS | folylpolyglutamate synthase |
| FZD4 | frizzled class receptor 4 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GOLGA8B | golgin A8 family, member B |
| GPX2 | glutathione peroxidase 2 |
| IL24 | interleukin 24 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF20B | kinesin family member 20B |
| KLC2 | kinesin light chain 2 |
| KLHL26 | kelch-like family member 26 |
| KPTN | kaptin (actin binding protein) |
| KRT75 | keratin 75, type II |
| LUC7L | LUC7-like (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MED22 | mediator complex subunit 22 |
| MID1IP1 | MID1 interacting protein 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MVP | major vault protein |
| NABP2 | nucleic acid binding protein 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| OCEL1 | occludin/ELL domain containing 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PALM | paralemmin |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLD2 | phospholipase D2 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| PYCARD | PYD and CARD domain containing |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS19 | regulator of G-protein signaling 19 |
| RNF130 | ring finger protein 130 |
| SAP30L | SAP30-like |
| SERTAD3 | SERTA domain containing 3 |
| SETD1B | SET domain containing 1B |
| SHPK | sedoheptulokinase |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPX | spexin hormone |
| STEAP3 | STEAP family member 3, metalloreductase |
| STK25 | serine/threonine kinase 25 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM260 | transmembrane protein 260 |
| TSPAN32 | tetraspanin 32 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC31 | tetratricopeptide repeat domain 31 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBXN2B | UBX domain protein 2B |
| UCKL1 | uridine-cytidine kinase 1-like 1 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF552 | zinc finger protein 552 |