| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the azathioprine-338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD2 | abhydrolase domain containing 2 |
| ACAN | aggrecan |
| AGRN | agrin |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARSA | arylsulfatase A |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BRAP | BRCA1 associated protein |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTBD2 | BTB (POZ) domain containing 2 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CDK10 | cyclin-dependent kinase 10 |
| CDYL | chromodomain protein, Y-like |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| COQ4 | coenzyme Q4 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DST | dystonin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFNB3 | ephrin-B3 |
| ELMO3 | engulfment and cell motility 3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHB1 | EPH receptor B1 |
| FAM188A | family with sequence similarity 188, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOSL2 | FOS-like antigen 2 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GH1 | growth hormone 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HOXB7 | homeobox B7 |
| IL11 | interleukin 11 |
| L1CAM | L1 cell adhesion molecule |
| LIG3 | ligase III, DNA, ATP-dependent |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LUZP1 | leucine zipper protein 1 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MINK1 | misshapen-like kinase 1 |
| MVB12B | multivesicular body subunit 12B |
| MYL10 | myosin, light chain 10, regulatory |
| NCLN | nicalin |
| NMT1 | N-myristoyltransferase 1 |
| NOTCH3 | notch 3 |
| NOX1 | NADPH oxidase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NXF2 | nuclear RNA export factor 2 |
| OGFR | opioid growth factor receptor |
| ORC4 | origin recognition complex, subunit 4 |
| PARVA | parvin, alpha |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHF2 | PHD finger protein 2 |
| PHF20 | PHD finger protein 20 |
| PLSCR3 | phospholipid scramblase 3 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM14 | PR domain containing 14 |
| PRMT7 | protein arginine methyltransferase 7 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTRF | polymerase I and transcript release factor |
| RANBP3 | RAN binding protein 3 |
| RBM48 | RNA binding motif protein 48 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TERT | telomerase reverse transcriptase |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM161A | transmembrane protein 161A |
| TMF1 | TATA element modulatory factor 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TTR | transthyretin |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| YIPF6 | Yip1 domain family, member 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| Symbol | Name |
|---|---|
| ADRA2B | adrenoceptor alpha 2B |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALPK1 | alpha-kinase 1 |
| APOL6 | apolipoprotein L, 6 |
| ARG1 | arginase 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARMC4 | armadillo repeat containing 4 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BHMT | betaine--homocysteine S-methyltransferase |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C21ORF62 | chromosome 21 open reading frame 62 |
| CA11 | carbonic anhydrase XI |
| CD101 | CD101 molecule |
| CD38 | CD38 molecule |
| CD5 | CD5 molecule |
| CDH22 | cadherin 22, type 2 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| DAGLA | diacylglycerol lipase, alpha |
| EGFL6 | EGF-like-domain, multiple 6 |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FGF22 | fibroblast growth factor 22 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| GDF10 | growth differentiation factor 10 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR157 | G protein-coupled receptor 157 |
| HAL | histidine ammonia-lyase |
| HAMP | hepcidin antimicrobial peptide |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HDAC11 | histone deacetylase 11 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HPGDS | hematopoietic prostaglandin D synthase |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INA | internexin neuronal intermediate filament protein, alpha |
| IQCG | IQ motif containing G |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1324 | KIAA1324 |
| LIAS | lipoic acid synthetase |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC31 | leucine rich repeat containing 31 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MEP1B | meprin A, beta |
| NLRP2 | NLR family, pyrin domain containing 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NXPH3 | neurexophilin 3 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PCDHA5 | protocadherin alpha 5 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| RASIP1 | Ras interacting protein 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCAI | suppressor of cancer cell invasion |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT2 | synaptotagmin II |
| TAOK1 | TAO kinase 1 |
| TGM5 | transglutaminase 5 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TUBA4B | tubulin, alpha 4b |
| TUBB1 | tubulin, beta 1 class VI |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZIC4 | Zic family member 4 |
| ZNF160 | zinc finger protein 160 |
| ZNF329 | zinc finger protein 329 |
| ZNF528 | zinc finger protein 528 |
| ZNF573 | zinc finger protein 573 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZXDC | ZXD family zinc finger C |