azathioprine-4667 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the azathioprine-4667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
B9D1 B9 protein domain 1
B9D2 B9 protein domain 2
BMP8A bone morphogenetic protein 8a
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK13 cyclin-dependent kinase 13
CDK20 cyclin-dependent kinase 20
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLCN7 chloride channel, voltage-sensitive 7
CLDN18 claudin 18
COL6A1 collagen, type VI, alpha 1
COPE coatomer protein complex, subunit epsilon
CST4 cystatin S
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGKA diacylglycerol kinase, alpha 80kDa
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
E2F4 E2F transcription factor 4, p107/p130-binding
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETV1 ets variant 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FBXL7 F-box and leucine-rich repeat protein 7
FGFR1 fibroblast growth factor receptor 1
FKBP10 FK506 binding protein 10, 65 kDa
FLJ42627 uncharacterized LOC645644
FRMD4B FERM domain containing 4B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPR161 G protein-coupled receptor 161
GYPB glycophorin B (MNS blood group)
HABP2 hyaluronan binding protein 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HGD homogentisate 1,2-dioxygenase
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOOK1 hook microtubule-tethering protein 1
HOXB3 homeobox B3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFNA17 interferon, alpha 17
IFT27 intraflagellar transport 27
IGHM immunoglobulin heavy constant mu
IL2 interleukin 2
IL22 interleukin 22
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD13 potassium channel tetramerization domain containing 13
KDM6B lysine (K)-specific demethylase 6B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LOC100286895 cell division cycle 27 homolog pseudogene
LRRN3 leucine rich repeat neuronal 3
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LST1 leukocyte specific transcript 1
MBD2 methyl-CpG binding domain protein 2
MTMR7 myotubularin related protein 7
MYL10 myosin, light chain 10, regulatory
N4BP2L2 NEDD4 binding protein 2-like 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OGFR opioid growth factor receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA2 pappalysin 2
PCNX pecanex homolog (Drosophila)
PHF7 PHD finger protein 7
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRKG1 protein kinase, cGMP-dependent, type I
PSD4 pleckstrin and Sec7 domain containing 4
PSG11 pregnancy specific beta-1-glycoprotein 11
PVR poliovirus receptor
RAD51D RAD51 paralog D
RIN3 Ras and Rab interactor 3
RNASE4 ribonuclease, RNase A family, 4
RPS14 ribosomal protein S14
SCN11A sodium channel, voltage gated, type XI alpha subunit
SENP6 SUMO1/sentrin specific peptidase 6
SHOX2 short stature homeobox 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A14 solute carrier family 22, member 14
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOX30 SRY (sex determining region Y)-box 30
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STOML1 stomatin (EPB72)-like 1
STX7 syntaxin 7
SULF1 sulfatase 1
TCP10L t-complex 10-like
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFA transforming growth factor, alpha
THY1 Thy-1 cell surface antigen
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM3 tripartite motif containing 3
WSB1 WD repeat and SOCS box containing 1
XCR1 chemokine (C motif) receptor 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF214 zinc finger protein 214
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM2 ADAM metallopeptidase domain 2
ADGRG2 adhesion G protein-coupled receptor G2
ARL14 ADP-ribosylation factor-like 14
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAK1 BCL2-antagonist/killer 1
C14ORF105 chromosome 14 open reading frame 105
C1RL complement component 1, r subcomponent-like
C22ORF46 chromosome 22 open reading frame 46
C9ORF40 chromosome 9 open reading frame 40
CA9 carbonic anhydrase IX
CADPS2 Ca++-dependent secretion activator 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD70 CD70 molecule
CD82 CD82 molecule
CENPO centromere protein O
CLDN11 claudin 11
CNTNAP3B contactin associated protein-like 3B
CPA4 carboxypeptidase A4
CRISP2 cysteine-rich secretory protein 2
CRYGC crystallin, gamma C
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR1 cysteinyl leukotriene receptor 1
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EGLN3 egl-9 family hypoxia-inducible factor 3
ELSPBP1 epididymal sperm binding protein 1
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FGF23 fibroblast growth factor 23
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GREB1L growth regulation by estrogen in breast cancer-like
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFT140 intraflagellar transport 140
IMPACT impact RWD domain protein
INF2 inverted formin, FH2 and WH2 domain containing
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0513 KIAA0513
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT20 keratin 20, type I
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MDFI MyoD family inhibitor
MITF microphthalmia-associated transcription factor
MMRN2 multimerin 2
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MUC3A mucin 3A, cell surface associated
MYOZ1 myozenin 1
NME5 NME/NM23 family member 5
NOTCH1 notch 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
NTF3 neurotrophin 3
OCA2 oculocutaneous albinism II
OLFM4 olfactomedin 4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDH12 protocadherin 12
PCOLCE procollagen C-endopeptidase enhancer
PORCN porcupine homolog (Drosophila)
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRR4 proline rich 4 (lacrimal)
RAD51B RAD51 paralog B
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RUSC2 RUN and SH3 domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCARA3 scavenger receptor class A, member 3
SCEL sciellin
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D2A SH2 domain containing 2A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SPATA1 spermatogenesis associated 1
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM180 transmembrane protein 180
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
ZBTB33 zinc finger and BTB domain containing 33
ZBTB39 zinc finger and BTB domain containing 39
ZFP30 ZFP30 zinc finger protein
ZNF816 zinc finger protein 816