azathioprine-5627 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the azathioprine-5627 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADORA3 adenosine A3 receptor
AIM1L absent in melanoma 1-like
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARTN artemin
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAIAP3 BAI1-associated protein 3
C1RL complement component 1, r subcomponent-like
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CCKBR cholecystokinin B receptor
CCNG2 cyclin G2
CCRL2 chemokine (C-C motif) receptor-like 2
CD48 CD48 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEND1 cell cycle exit and neuronal differentiation 1
CLDN18 claudin 18
CLTA clathrin, light chain A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COLEC11 collectin sub-family member 11
DEFA4 defensin, alpha 4, corticostatin
DEFB126 defensin, beta 126
DIO2 deiodinase, iodothyronine, type II
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHB2 EPH receptor B2
EXD3 exonuclease 3'-5' domain containing 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FABP4 fatty acid binding protein 4, adipocyte
FBXO31 F-box protein 31
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FOSL2 FOS-like antigen 2
FPR2 formyl peptide receptor 2
FRMD4B FERM domain containing 4B
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GLIPR1 GLI pathogenesis-related 1
GTDC1 glycosyltransferase-like domain containing 1
HIST1H1B histone cluster 1, H1b
HOXA10 homeobox A10
HOXB3 homeobox B3
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGFBP5 insulin-like growth factor binding protein 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIF21B kinesin family member 21B
KIF25 kinesin family member 25
KSR1 kinase suppressor of ras 1
LDB3 LIM domain binding 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAN1A2 mannosidase, alpha, class 1A, member 2
MAOB monoamine oxidase B
MAP1A microtubule-associated protein 1A
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCF2L MCF.2 cell line derived transforming sequence-like
MOBP myelin-associated oligodendrocyte basic protein
MRPS12 mitochondrial ribosomal protein S12
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
NKX2-5 NK2 homeobox 5
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
PCDHB6 protocadherin beta 6
PICK1 protein interacting with PRKCA 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PRKCB protein kinase C, beta
PRUNE2 prune homolog 2 (Drosophila)
PTAFR platelet-activating factor receptor
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SFRP4 secreted frizzled-related protein 4
SH2D3A SH2 domain containing 3A
SH3GL3 SH3-domain GRB2-like 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SYN2 synapsin II
TAPBP TAP binding protein (tapasin)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGM4 transglutaminase 4
TNN tenascin N
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
UBOX5 U-box domain containing 5
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
WAS Wiskott-Aldrich syndrome
WDR78 WD repeat domain 78
WSCD1 WSC domain containing 1
XAF1 XIAP associated factor 1
ZNF682 zinc finger protein 682
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AFAP1 actin filament associated protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
ATAT1 alpha tubulin acetyltransferase 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CD82 CD82 molecule
CHRM3 cholinergic receptor, muscarinic 3
CRIP1 cysteine-rich protein 1 (intestinal)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DIXDC1 DIX domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FAM131A family with sequence similarity 131, member A
FAM155A family with sequence similarity 155, member A
FAM155B family with sequence similarity 155, member B
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
FLJ22184
GFI1 growth factor independent 1 transcription repressor
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR27 G protein-coupled receptor 27
GRPR gastrin-releasing peptide receptor
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HMGN5 high mobility group nucleosome binding domain 5
HOXA4 homeobox A4
HOXB2 homeobox B2
HOXC8 homeobox C8
INO80D INO80 complex subunit D
INPP1 inositol polyphosphate-1-phosphatase
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0319L KIAA0319-like
KLF11 Kruppel-like factor 11
LINC00597 long intergenic non-protein coding RNA 597
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANBA mannosidase, beta A, lysosomal
MANSC1 MANSC domain containing 1
MED9 mediator complex subunit 9
MEFV Mediterranean fever
MORC3 MORC family CW-type zinc finger 3
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NDE1 nudE neurodevelopment protein 1
NPTX1 neuronal pentraxin I
NT5E 5'-nucleotidase, ecto (CD73)
NXPH4 neurexophilin 4
OVOL1 ovo-like zinc finger 1
PADI1 peptidyl arginine deiminase, type I
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
PMCH pro-melanin-concentrating hormone
PRSS53 protease, serine, 53
QPCTL glutaminyl-peptide cyclotransferase-like
RAB30 RAB30, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCAN3 RCAN family member 3
RRAGB Ras-related GTP binding B
RSF1 remodeling and spacing factor 1
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SSTR4 somatostatin receptor 4
STRN striatin, calmodulin binding protein
SULT4A1 sulfotransferase family 4A, member 1
SYNC syncoilin, intermediate filament protein
TGFBR3 transforming growth factor, beta receptor III
THOP1 thimet oligopeptidase 1
TM6SF1 transmembrane 6 superfamily member 1
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TRABD TraB domain containing
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF446 zinc finger protein 446
ZNF532 zinc finger protein 532