azathioprine Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. (Chemical Entities of Biological Interest Ontology, CHEBI_2948)
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Genes

9 genes co-occuring with the biological term azathioprine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AOX1	aldehyde oxidase 1
GSTA2	glutathione S-transferase alpha 2
IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
MSH2	mutS homolog 2
PTCH1	patched 1
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
TPMT	thiopurine S-methyltransferase
XDH	xanthine dehydrogenase