azlocillin-2727 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the azlocillin-2727 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADORA1 adenosine A1 receptor
AHCYL1 adenosylhomocysteinase-like 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATG12 autophagy related 12
AURKA aurora kinase A
BMP7 bone morphogenetic protein 7
C11ORF63 chromosome 11 open reading frame 63
CCDC181 coiled-coil domain containing 181
CCDC28B coiled-coil domain containing 28B
CCL22 chemokine (C-C motif) ligand 22
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEMP1 cementum protein 1
COL13A1 collagen, type XIII, alpha 1
DAPK3 death-associated protein kinase 3
DBT dihydrolipoamide branched chain transacylase E2
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DMPK dystrophia myotonica-protein kinase
EDIL3 EGF-like repeats and discoidin I-like domains 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FADS3 fatty acid desaturase 3
FAM189A1 family with sequence similarity 189, member A1
FBLN1 fibulin 1
FGF16 fibroblast growth factor 16
FGFR2 fibroblast growth factor receptor 2
FMO5 flavin containing monooxygenase 5
GP6 glycoprotein VI (platelet)
GPATCH4 G patch domain containing 4
GRHL2 grainyhead-like 2 (Drosophila)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HIST1H2AJ histone cluster 1, H2aj
HOXA10 homeobox A10
HOXA3 homeobox A3
HOXB7 homeobox B7
HPCAL4 hippocalcin like 4
ICAM1 intercellular adhesion molecule 1
IFT74 intraflagellar transport 74
IGHA1 immunoglobulin heavy constant alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGL immunoglobulin lambda locus
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF4 interferon regulatory factor 4
ISYNA1 inositol-3-phosphate synthase 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KIF5A kinesin family member 5A
KRT31 keratin 31, type I
KXD1 KxDL motif containing 1
LMTK2 lemur tyrosine kinase 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEA5 melanoma antigen family A5
MAN1A2 mannosidase, alpha, class 1A, member 2
NADK NAD kinase
NCR2 natural cytotoxicity triggering receptor 2
NEBL nebulette
NOS1 nitric oxide synthase 1 (neuronal)
NOV nephroblastoma overexpressed
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSBPL7 oxysterol binding protein-like 7
PAX4 paired box 4
PCDHB1 protocadherin beta 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEG10 paternally expressed 10
PIP prolactin-induced protein
PKP1 plakophilin 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLH polymerase (DNA directed), eta
PTCRA pre T-cell antigen receptor alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRM protein tyrosine phosphatase, receptor type, M
RIF1 replication timing regulatory factor 1
SARM1 sterile alpha and TIR motif containing 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOX15 SRY (sex determining region Y)-box 15
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STMN2 stathmin 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SYNDIG1 synapse differentiation inducing 1
TBX5 T-box 5
TEX13B testis expressed 13B
TFDP3 transcription factor Dp family, member 3
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
UBE2B ubiquitin-conjugating enzyme E2B
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
XDH xanthine dehydrogenase
ZNF780B zinc finger protein 780B
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACP6 acid phosphatase 6, lysophosphatidic
ACYP2 acylphosphatase 2, muscle type
AKTIP AKT interacting protein
AMH anti-Mullerian hormone
C16ORF45 chromosome 16 open reading frame 45
CBX7 chromobox homolog 7
CCDC132 coiled-coil domain containing 132
CCDC57 coiled-coil domain containing 57
CCDC69 coiled-coil domain containing 69
CCDC71 coiled-coil domain containing 71
CD3EAP CD3e molecule, epsilon associated protein
CDK20 cyclin-dependent kinase 20
CDR2L cerebellar degeneration-related protein 2-like
CHMP1A charged multivesicular body protein 1A
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIP2 CAP-GLY domain containing linker protein 2
CRYGC crystallin, gamma C
CRYL1 crystallin, lambda 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CTSO cathepsin O
DDN dendrin
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
EGR2 early growth response 2
FAM127B family with sequence similarity 127, member B
FER fer (fps/fes related) tyrosine kinase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
GPR75 G protein-coupled receptor 75
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HLA-DMB major histocompatibility complex, class II, DM beta
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1107 KIAA1107
KLK5 kallikrein-related peptidase 5
LGALS4 lectin, galactoside-binding, soluble, 4
LOC257152 uncharacterized LOC257152
LPAR6 lysophosphatidic acid receptor 6
LSP1 lymphocyte-specific protein 1
LTBP3 latent transforming growth factor beta binding protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAB21L1 mab-21-like 1 (C. elegans)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MEP1B meprin A, beta
MKL2 MKL/myocardin-like 2
MTCP1 mature T-cell proliferation 1
MVP major vault protein
MX2 MX dynamin-like GTPase 2
MYOZ3 myozenin 3
NKX3-2 NK3 homeobox 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
NT5DC3 5'-nucleotidase domain containing 3
NTSR1 neurotensin receptor 1 (high affinity)
OTUD3 OTU deubiquitinase 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDH12 protocadherin 12
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLA2G12A phospholipase A2, group XIIA
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POMZP3 POM121 and ZP3 fusion
PRSS53 protease, serine, 53
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCAN3 RCAN family member 3
RHBDD3 rhomboid domain containing 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RRAGB Ras-related GTP binding B
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERGEF secretion regulating guanine nucleotide exchange factor
SGPP1 sphingosine-1-phosphate phosphatase 1
SHPK sedoheptulokinase
SIRT6 sirtuin 6
SLC35E3 solute carrier family 35, member E3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPAG4 sperm associated antigen 4
SV2A synaptic vesicle glycoprotein 2A
TBL1Y transducin (beta)-like 1, Y-linked
TEAD3 TEA domain family member 3
TMC5 transmembrane channel-like 5
TMEM254 transmembrane protein 254
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNRC6B trinucleotide repeat containing 6B
TUBB2A tubulin, beta 2A class IIa
XAB2 XPA binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZFAND3 zinc finger, AN1-type domain 3
ZNF276 zinc finger protein 276
ZNF778 zinc finger protein 778