azlocillin-5788 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the azlocillin-5788 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACTC1 actin, alpha, cardiac muscle 1
ADRBK2 adrenergic, beta, receptor kinase 2
ARHGAP33 Rho GTPase activating protein 33
ASIC1 acid sensing (proton gated) ion channel 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTF3P11 basic transcription factor 3 pseudogene 11
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM3 cell adhesion molecule 3
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD40 CD40 molecule, TNF receptor superfamily member 5
CLCN6 chloride channel, voltage-sensitive 6
CLDN17 claudin 17
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CTNS cystinosin, lysosomal cystine transporter
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DKFZP434C153 DKFZP434C153 protein
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FGF1 fibroblast growth factor 1 (acidic)
FYB FYN binding protein
GHRHR growth hormone releasing hormone receptor
GJD2 gap junction protein, delta 2, 36kDa
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GSTM5 glutathione S-transferase mu 5
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HEXA hexosaminidase A (alpha polypeptide)
HFE hemochromatosis
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGL immunoglobulin lambda locus
IL2RA interleukin 2 receptor, alpha
IRF5 interferon regulatory factor 5
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KRT34 keratin 34, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIME1 Lck interacting transmembrane adaptor 1
LOX lysyl oxidase
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRTM1 leucine-rich repeats and transmembrane domains 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGIX MAGI family member, X-linked
MAP2K5 mitogen-activated protein kinase kinase 5
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD2 methyl-CpG binding domain protein 2
MECOM MDS1 and EVI1 complex locus
MPZ myelin protein zero
MST1 macrophage stimulating 1
MZF1 myeloid zinc finger 1
NDNF neuron-derived neurotrophic factor
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAIP2B poly(A) binding protein interacting protein 2B
PDE4D phosphodiesterase 4D, cAMP-specific
PHC3 polyhomeotic homolog 3 (Drosophila)
PHOX2B paired-like homeobox 2b
PICK1 protein interacting with PRKCA 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP prolactin-induced protein
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
REEP1 receptor accessory protein 1
SERHL2 serine hydrolase-like 2
SH2D3C SH2 domain containing 3C
SH3GL3 SH3-domain GRB2-like 3
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPEF1 sperm flagellar 1
TADA3 transcriptional adaptor 3
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TEX15 testis expressed 15
TFCP2L1 transcription factor CP2-like 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UNC13A unc-13 homolog A (C. elegans)
USP22 ubiquitin specific peptidase 22
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WAPAL wings apart-like homolog (Drosophila)
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
ZNF117 zinc finger protein 117
ZNF224 zinc finger protein 224
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ATAT1 alpha tubulin acetyltransferase 1
AXIN1 axin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BMP15 bone morphogenetic protein 15
C17ORF53 chromosome 17 open reading frame 53
C1ORF105 chromosome 1 open reading frame 105
CEP170B centrosomal protein 170B
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CLDN14 claudin 14
CLEC2B C-type lectin domain family 2, member B
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPA4 carboxypeptidase A4
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4A DENN/MADD domain containing 4A
DNAL4 dynein, axonemal, light chain 4
EHD3 EH-domain containing 3
EXOC6B exocyst complex component 6B
FAM86C1 family with sequence similarity 86, member C1
FBXL15 F-box and leucine-rich repeat protein 15
FBXL4 F-box and leucine-rich repeat protein 4
FBXL7 F-box and leucine-rich repeat protein 7
FPGS folylpolyglutamate synthase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR19 G protein-coupled receptor 19
GTPBP2 GTP binding protein 2
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HIST1H3C histone cluster 1, H3c
HIST1H4D histone cluster 1, H4d
HOXA2 homeobox A2
IFI44L interferon-induced protein 44-like
IMPACT impact RWD domain protein
KRT8P12 keratin 8 pseudogene 12
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO7 LIM domain 7
LYRM9 LYR motif containing 9
MAGEA5 melanoma antigen family A5
MCTP2 multiple C2 domains, transmembrane 2
METTL16 methyltransferase like 16
MON1B MON1 secretory trafficking family member B
MUC3A mucin 3A, cell surface associated
MXRA8 matrix-remodelling associated 8
MYL9 myosin, light chain 9, regulatory
NID2 nidogen 2 (osteonidogen)
NOTCH1 notch 1
NUBP2 nucleotide binding protein 2
OLFML2A olfactomedin-like 2A
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PELI1 pellino E3 ubiquitin protein ligase 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PLXNB3 plexin B3
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PRKX protein kinase, X-linked
PRR15L proline rich 15-like
PTPRE protein tyrosine phosphatase, receptor type, E
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RNF146 ring finger protein 146
RUSC2 RUN and SH3 domain containing 2
SECISBP2 SECIS binding protein 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC25A40 solute carrier family 25, member 40
SND1-IT1 SND1 intronic transcript 1
SOBP sine oculis binding protein homolog (Drosophila)
SOD3 superoxide dismutase 3, extracellular
SPRYD7 SPRY domain containing 7
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TBP TATA box binding protein
TCTN2 tectonic family member 2
TEAD3 TEA domain family member 3
TM7SF2 transmembrane 7 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM212 transmembrane protein 212
TMEM242 transmembrane protein 242
UGT8 UDP glycosyltransferase 8
ZMAT5 zinc finger, matrin-type 5
ZNF141 zinc finger protein 141
ZNF324 zinc finger protein 324
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZW10 zw10 kinetochore protein