azoospermia; oligospermia Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group reproduction (Genetic Association Database)
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Genes

51 genes associated with the disease azoospermia; oligospermia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
AR androgen receptor
BRCA2 breast cancer 2, early onset
BRDT bromodomain, testis-specific
CAMK4 calcium/calmodulin-dependent protein kinase IV
CREM cAMP responsive element modulator
DAZL deleted in azoospermia-like
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DMC1 DNA meiotic recombinase 1
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FHL5 four and a half LIM domains 5
FKBP6 FK506 binding protein 6, 36kDa
H2AFX H2A histone family, member X
IL1B interleukin 1, beta
KDM3A lysine (K)-specific demethylase 3A
KIF17 kinesin family member 17
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MSH4 mutS homolog 4
MSH5 mutS homolog 5
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
PIWIL1 piwi-like RNA-mediated gene silencing 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PIWIL3 piwi-like RNA-mediated gene silencing 3
PIWIL4 piwi-like RNA-mediated gene silencing 4
PRM1 protamine 1
PRM2 protamine 2
REC8 REC8 meiotic recombination protein
SMC1B structural maintenance of chromosomes 1B
SPATA22 spermatogenesis associated 22
SPO11 SPO11 meiotic protein covalently bound to DSB
STRA8 stimulated by retinoic acid 8
SYCP1 synaptonemal complex protein 1
SYCP2 synaptonemal complex protein 2
TEX11 testis expressed 11
TEX14 testis expressed 14
TEX15 testis expressed 15
TNP1 transition protein 1 (during histone to protamine replacement)
TNP2 transition protein 2 (during histone to protamine replacement)
TSSK4 testis-specific serine kinase 4
UBE2B ubiquitin-conjugating enzyme E2B
USP26 ubiquitin specific peptidase 26
USP9Y ubiquitin specific peptidase 9, Y-linked
XPC xeroderma pigmentosum, complementation group C
YBX2 Y box binding protein 2