azoospermia Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen. (Experimental Factor Ontology, EFO_0000279)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:14227
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Genes

26 genes associated with the disease azoospermia in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
PTK2 protein tyrosine kinase 2 1.74614
CHSY1 chondroitin sulfate synthase 1 1.7248
CFB complement factor B 1.69674
HLA-DRA major histocompatibility complex, class II, DR alpha 1.69412
TDRKH tudor and KH domain containing 1.64201
C6ORF10 chromosome 6 open reading frame 10 1.62786
FAT1 FAT atypical cadherin 1 1.60858
FAM155A family with sequence similarity 155, member A 1.53844
BTNL2 butyrophilin-like 2 1.50906
MOBP myelin-associated oligodendrocyte basic protein 1.50423
SOX5 SRY (sex determining region Y)-box 5 1.48714
LOC100289473 cytoskeleton associated protein 2-like pseudogene 1.48714
PTPRD protein tyrosine phosphatase, receptor type, D 1.36554
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 1.32035
SLCO5A1 solute carrier organic anion transporter family, member 5A1 1.30111
MARCO macrophage receptor with collagenous structure 1.19609
ESR2 estrogen receptor 2 (ER beta) 1.18963
ANAPC4 anaphase promoting complex subunit 4 1.1676
ASTN2 astrotactin 2 1.16218
NOTCH4 notch 4 1.10153
AOX2P aldehyde oxidase 2 pseudogene 1.03065
DNAH10 dynein, axonemal, heavy chain 10 1.0216
OR56A4 olfactory receptor, family 56, subfamily A, member 4 0.991083
PHF2P1 PHD finger protein 2 pseudogene 1 0.974905
LHFPL3 lipoma HMGIC fusion partner-like 3 0.918934
TSNARE1 t-SNARE domain containing 1 0.884