azoospermia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen. (Experimental Factor Ontology, EFO_0000279)
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Genes

86 genes co-occuring with the biological term azoospermia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AMH anti-Mullerian hormone
AR androgen receptor
ART3 ADP-ribosyltransferase 3
AZF1 azoospermia factor 1
BCL2 B-cell CLL/lymphoma 2
BOLL boule-like RNA-binding protein
BPY2 basic charge, Y-linked, 2
BRCA2 breast cancer 2, early onset
BRDT bromodomain, testis-specific
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CLU clusterin
CRISP1 cysteine-rich secretory protein 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAZ1 deleted in azoospermia 1
DAZL deleted in azoospermia-like
DDR1 discoidin domain receptor tyrosine kinase 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FKBP6 FK506 binding protein 6, 36kDa
FSHB follicle stimulating hormone, beta polypeptide
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H2BFWT H2B histone family, member W, testis-specific
HEXA hexosaminidase A (alpha polypeptide)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HNRNPL heterogeneous nuclear ribonucleoprotein L
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
INHBA inhibin, beta A
KITLG KIT ligand
KLHL10 kelch-like family member 10
MIR141 microRNA 141
MIR429 microRNA 429
MIR7-1 microRNA 7-1
MLH3 mutL homolog 3
MSH5 mutS homolog 5
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NANOS1 nanos homolog 1 (Drosophila)
NCOA1 nuclear receptor coactivator 1
NCOA4 nuclear receptor coactivator 4
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR5A1 nuclear receptor subfamily 5, group A, member 1
PACRG PARK2 co-regulated
PARP2 poly (ADP-ribose) polymerase 2
PEPD peptidase D
PGAM4 phosphoglycerate mutase family member 4
PIP prolactin-induced protein
PRDM9 PR domain containing 9
PRM2 protamine 2
PYGO2 pygopus family PHD finger 2
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1
SEPT12 septin 12
SIRPA signal-regulatory protein alpha
SIRPG signal-regulatory protein gamma
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SOX5 SRY (sex determining region Y)-box 5
SPAG11B sperm associated antigen 11B
SRY sex determining region Y
SYCP3 synaptonemal complex protein 3
TEX101 testis expressed 101
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
TGIF2LY TGFB-induced factor homeobox 2-like, Y-linked
TUBA4A tubulin, alpha 4a
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP26 ubiquitin specific peptidase 26
WIPF3 WAS/WASL interacting protein family, member 3
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF230 zinc finger protein 230