| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the aztreonam-1435 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACVR2A | activin A receptor, type IIA |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AGRN | agrin |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| CACYBP | calcyclin binding protein |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD320 | CD320 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHN2 | chimerin 2 |
| CUL3 | cullin 3 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DSCR3 | Down syndrome critical region 3 |
| DUS2 | dihydrouridine synthase 2 |
| EHD1 | EH-domain containing 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| EXOSC4 | exosome component 4 |
| FAM89B | family with sequence similarity 89, member B |
| FBXO42 | F-box protein 42 |
| GPR12 | G protein-coupled receptor 12 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HBB | hemoglobin, beta |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXD1 | homeobox D1 |
| HRH3 | histamine receptor H3 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IGF1R | insulin-like growth factor 1 receptor |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| ING1 | inhibitor of growth family, member 1 |
| JUND | jun D proto-oncogene |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MED14 | mediator complex subunit 14 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MIIP | migration and invasion inhibitory protein |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MPZL1 | myelin protein zero-like 1 |
| MYOZ1 | myozenin 1 |
| MYT1 | myelin transcription factor 1 |
| NADK | NAD kinase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOA3 | nuclear receptor coactivator 3 |
| ONECUT2 | one cut homeobox 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| QRICH1 | glutamine-rich 1 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RPS11 | ribosomal protein S11 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCCPDH | saccharopine dehydrogenase (putative) |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SFN | stratifin |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| SMAD3 | SMAD family member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP100 | SP100 nuclear antigen |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SYNGR1 | synaptogyrin 1 |
| TBC1D4 | TBC1 domain family, member 4 |
| THEM6 | thioesterase superfamily member 6 |
| THTPA | thiamine triphosphatase |
| TMEM161A | transmembrane protein 161A |
| TMEM206 | transmembrane protein 206 |
| TOR4A | torsin family 4, member A |
| TSC2 | tuberous sclerosis 2 |
| TUBB3 | tubulin, beta 3 class III |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZNF219 | zinc finger protein 219 |
| ZNF337 | zinc finger protein 337 |
| ZNF671 | zinc finger protein 671 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMT1 | acidic residue methyltransferase 1 |
| ATF1 | activating transcription factor 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C1D | C1D nuclear receptor corepressor |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CDC73 | cell division cycle 73 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CFL1 | cofilin 1 (non-muscle) |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CRY1 | cryptochrome circadian clock 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| CYCS | cytochrome c, somatic |
| DCK | deoxycytidine kinase |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| DYSF | dysferlin |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FADS2 | fatty acid desaturase 2 |
| FAM35A | family with sequence similarity 35, member A |
| FAM46A | family with sequence similarity 46, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FBXO5 | F-box protein 5 |
| FRG1 | FSHD region gene 1 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GPN3 | GPN-loop GTPase 3 |
| HMGB2 | high mobility group box 2 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LYRM2 | LYR motif containing 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MIS18BP1 | MIS18 binding protein 1 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MTMR6 | myotubularin related protein 6 |
| MYL12B | myosin, light chain 12B, regulatory |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NMI | N-myc (and STAT) interactor |
| NUPL1 | nucleoporin like 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCNA | proliferating cell nuclear antigen |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| PRRC1 | proline-rich coiled-coil 1 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB5B | RAB5B, member RAS oncogene family |
| RANBP6 | RAN binding protein 6 |
| RBL1 | retinoblastoma-like 1 |
| RCOR1 | REST corepressor 1 |
| RPL26 | ribosomal protein L26 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SCAF8 | SR-related CTD-associated factor 8 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SRBD1 | S1 RNA binding domain 1 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| STXBP3 | syntaxin binding protein 3 |
| SUCO | SUN domain containing ossification factor |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TGS1 | trimethylguanosine synthase 1 |
| TMEM14A | transmembrane protein 14A |
| TMEM38B | transmembrane protein 38B |
| TRIT1 | tRNA isopentenyltransferase 1 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TTF2 | transcription termination factor, RNA polymerase II |
| TTI1 | TELO2 interacting protein 1 |
| TUBA1A | tubulin, alpha 1a |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VRK2 | vaccinia related kinase 2 |
| WDR43 | WD repeat domain 43 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZNF124 | zinc finger protein 124 |
| ZNF217 | zinc finger protein 217 |
