| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the aztreonam-2118 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BFSP1 | beaded filament structural protein 1, filensin |
| BICC1 | BicC family RNA binding protein 1 |
| BMP4 | bone morphogenetic protein 4 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CCDC28B | coiled-coil domain containing 28B |
| CDK16 | cyclin-dependent kinase 16 |
| CEP164 | centrosomal protein 164kDa |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CST4 | cystatin S |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| ELL | elongation factor RNA polymerase II |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR85 | G protein-coupled receptor 85 |
| HNMT | histamine N-methyltransferase |
| HOXB5 | homeobox B5 |
| HOXC10 | homeobox C10 |
| IFI44L | interferon-induced protein 44-like |
| IFNA17 | interferon, alpha 17 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCE | IQ motif containing E |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KHSRP | KH-type splicing regulatory protein |
| KLK10 | kallikrein-related peptidase 10 |
| KRT37 | keratin 37, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIMK1 | LIM domain kinase 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MUC3A | mucin 3A, cell surface associated |
| MUC3B | mucin 3B, cell surface associated |
| NF1 | neurofibromin 1 |
| NGF | nerve growth factor (beta polypeptide) |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDH12 | protocadherin 12 |
| PER3 | period circadian clock 3 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLK3 | polo-like kinase 3 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKCA | protein kinase C, alpha |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRPF18 | pre-mRNA processing factor 18 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RBL2 | retinoblastoma-like 2 |
| REST | RE1-silencing transcription factor |
| RGCC | regulator of cell cycle |
| RGS12 | regulator of G-protein signaling 12 |
| RGS4 | regulator of G-protein signaling 4 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD3 | SMAD family member 3 |
| SMAD5 | SMAD family member 5 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP100 | SP100 nuclear antigen |
| STRN3 | striatin, calmodulin binding protein 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX2 | syntaxin 2 |
| SUSD4 | sushi domain containing 4 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFCP2 | transcription factor CP2 |
| TGFA | transforming growth factor, alpha |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TLN2 | talin 2 |
| TLX2 | T-cell leukemia homeobox 2 |
| TMEM209 | transmembrane protein 209 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF629 | zinc finger protein 629 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APH1B | APH1B gamma secretase subunit |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CLSPN | claspin |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ECM1 | extracellular matrix protein 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HIRA | histone cell cycle regulator |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BF | histone cluster 1, H2bf |
| HOXC13 | homeobox C13 |
| HOXC5 | homeobox C5 |
| IL17RA | interleukin 17 receptor A |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0556 | KIAA0556 |
| KIAA0894 | KIAA0894 protein |
| KLHL3 | kelch-like family member 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRC14 | leucine rich repeat containing 14 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED18 | mediator complex subunit 18 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NMB | neuromedin B |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OLFML2A | olfactomedin-like 2A |
| OSR2 | odd-skipped related transciption factor 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNA3 | plexin A3 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RECQL4 | RecQ protein-like 4 |
| RIN1 | Ras and Rab interactor 1 |
| RNF25 | ring finger protein 25 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIX1 | SIX homeobox 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPATA7 | spermatogenesis associated 7 |
| SPEG | SPEG complex locus |
| STK16 | serine/threonine kinase 16 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM45 | tripartite motif containing 45 |
| TRMT61A | tRNA methyltransferase 61A |
| TUBG2 | tubulin, gamma 2 |
| TXLNG | taxilin gamma |
| UBQLN4 | ubiquilin 4 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF107 | zinc finger protein 107 |
| ZNF160 | zinc finger protein 160 |
| ZNF189 | zinc finger protein 189 |
| ZNF215 | zinc finger protein 215 |
| ZNF408 | zinc finger protein 408 |
| ZNF83 | zinc finger protein 83 |
