aztreonam-2282 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the aztreonam-2282 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADCK2 aarF domain containing kinase 2
ADRA1B adrenoceptor alpha 1B
ALB albumin
AMPD3 adenosine monophosphate deaminase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ARG1 arginase 1
ASPN asporin
ATXN7L3B ataxin 7-like 3B
BMP10 bone morphogenetic protein 10
BST2 bone marrow stromal cell antigen 2
C10ORF95 chromosome 10 open reading frame 95
C14ORF79 chromosome 14 open reading frame 79
C21ORF2 chromosome 21 open reading frame 2
CA9 carbonic anhydrase IX
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CERS4 ceramide synthase 4
CFHR4 complement factor H-related 4
CNN1 calponin 1, basic, smooth muscle
CTSF cathepsin F
DES desmin
DLC1 DLC1 Rho GTPase activating protein
DMRT1 doublesex and mab-3 related transcription factor 1
DMXL2 Dmx-like 2
DOCK10 dedicator of cytokinesis 10
DOCK6 dedicator of cytokinesis 6
EDA ectodysplasin A
EML2 echinoderm microtubule associated protein like 2
EXOC7 exocyst complex component 7
FGA fibrinogen alpha chain
FLNC filamin C, gamma
GAS7 growth arrest-specific 7
GPR20 G protein-coupled receptor 20
GRM8 glutamate receptor, metabotropic 8
HFE hemochromatosis
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK5 potassium channel, two pore domain subfamily K, member 5
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAN1A2 mannosidase, alpha, class 1A, member 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MUC6 mucin 6, oligomeric mucus/gel-forming
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OSBPL10 oxysterol binding protein-like 10
PARD6B par-6 family cell polarity regulator beta
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFD platelet derived growth factor D
PDZK1IP1 PDZK1 interacting protein 1
PEX3 peroxisomal biogenesis factor 3
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PODNL1 podocan-like 1
POFUT1 protein O-fucosyltransferase 1
POU3F2 POU class 3 homeobox 2
POU5F1B POU class 5 homeobox 1B
PRKCA protein kinase C, alpha
RAB33A RAB33A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
REST RE1-silencing transcription factor
RIMS2 regulating synaptic membrane exocytosis 2
RNF6 ring finger protein (C3H2C3 type) 6
RPA4 replication protein A4, 30kDa
SAFB scaffold attachment factor B
SBNO1 strawberry notch homolog 1 (Drosophila)
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SERHL2 serine hydrolase-like 2
SH2D2A SH2 domain containing 2A
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SNPH syntaphilin
SRGN serglycin
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TM4SF4 transmembrane 4 L six family member 4
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM144 transmembrane protein 144
TMEM63A transmembrane protein 63A
TNS1 tensin 1
TPMT thiopurine S-methyltransferase
TTC38 tetratricopeptide repeat domain 38
UGT8 UDP glycosyltransferase 8
WSCD1 WSC domain containing 1
ZFHX4 zinc finger homeobox 4
ZFP64 ZFP64 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF154 zinc finger protein 154
ZNF286A zinc finger protein 286A
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABLIM3 actin binding LIM protein family, member 3
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADTRP androgen-dependent TFPI-regulating protein
APOLD1 apolipoprotein L domain containing 1
ARMC4 armadillo repeat containing 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
BRPF1 bromodomain and PHD finger containing, 1
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CDK18 cyclin-dependent kinase 18
CDR2L cerebellar degeneration-related protein 2-like
CES3 carboxylesterase 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLSTN2 calsyntenin 2
CPA4 carboxypeptidase A4
CXXC4 CXXC finger protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
ELP6 elongator acetyltransferase complex subunit 6
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM76A family with sequence similarity 76, member A
FANCE Fanconi anemia, complementation group E
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FLT4 fms-related tyrosine kinase 4
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GRB7 growth factor receptor-bound protein 7
GSAP gamma-secretase activating protein
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HCFC2 host cell factor C2
HIST1H2AI histone cluster 1, H2ai
HOXC10 homeobox C10
HOXC4 homeobox C4
HS1BP3 HCLS1 binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
INHA inhibin, alpha
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KLHDC8A kelch domain containing 8A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KREMEN2 kringle containing transmembrane protein 2
LAMB3 laminin, beta 3
LAMP3 lysosomal-associated membrane protein 3
LOXL3 lysyl oxidase-like 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC23 leucine rich repeat containing 23
MAGEF1 melanoma antigen family F1
MALL mal, T-cell differentiation protein-like
MYO1D myosin ID
MYO1E myosin IE
NOL10 nucleolar protein 10
NT5DC3 5'-nucleotidase domain containing 3
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPT2 palmitoyl-protein thioesterase 2
PRDM16 PR domain containing 16
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFXAP regulatory factor X-associated protein
RNF208 ring finger protein 208
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMYD5 SMYD family member 5
SP1 Sp1 transcription factor
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TESK2 testis-specific kinase 2
TFF2 trefoil factor 2
TIGD6 tigger transposable element derived 6
TMEM104 transmembrane protein 104
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSNAXIP1 translin-associated factor X interacting protein 1
USB1 U6 snRNA biogenesis 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB40 zinc finger and BTB domain containing 40
ZNF76 zinc finger protein 76