| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the aztreonam-5110 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACRV1 | acrosomal vesicle protein 1 |
| ACVR1B | activin A receptor, type IB |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BMP1 | bone morphogenetic protein 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CD58 | CD58 molecule |
| CD68 | CD68 molecule |
| CD7 | CD7 molecule |
| CEMP1 | cementum protein 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC7A | C-type lectin domain family 7, member A |
| CLSTN3 | calsyntenin 3 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DMC1 | DNA meiotic recombinase 1 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DOK4 | docking protein 4 |
| DRD2 | dopamine receptor D2 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GAS7 | growth arrest-specific 7 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GRM7 | glutamate receptor, metabotropic 7 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HBB | hemoglobin, beta |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| IL1RN | interleukin 1 receptor antagonist |
| IL33R | interleukin 33 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MMP3 | matrix metallopeptidase 3 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYO1F | myosin IF |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUP214 | nucleoporin 214kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKCQ | protein kinase C, theta |
| PROL1 | proline rich, lacrimal 1 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RABGAP1 | RAB GTPase activating protein 1 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RGS12 | regulator of G-protein signaling 12 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SFTPB | surfactant protein B |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STOML1 | stomatin (EPB72)-like 1 |
| SVIL | supervillin |
| TACR1 | tachykinin receptor 1 |
| TBX10 | T-box 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TFDP3 | transcription factor Dp family, member 3 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM231 | transmembrane protein 231 |
| TRA | T cell receptor alpha locus |
| TUBA4B | tubulin, alpha 4b |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USP34 | ubiquitin specific peptidase 34 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFAP1 | actin filament associated protein 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARRB2 | arrestin, beta 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BMP15 | bone morphogenetic protein 15 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EAF2 | ELL associated factor 2 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EFNA3 | ephrin-A3 |
| EHF | ets homologous factor |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERF | Ets2 repressor factor |
| GALK1 | galactokinase 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1T | histone cluster 1, H1t |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA2 | interferon, alpha 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF2 | Kruppel-like factor 2 |
| KLHL36 | kelch-like family member 36 |
| KRT86 | keratin 86, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC257152 | uncharacterized LOC257152 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MICALL2 | MICAL-like 2 |
| MIS18BP1 | MIS18 binding protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NLK | nemo-like kinase |
| NTF3 | neurotrophin 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OLFML3 | olfactomedin-like 3 |
| OSBP2 | oxysterol binding protein 2 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLAC8 | placenta-specific 8 |
| POLH | polymerase (DNA directed), eta |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR14L | proline rich 14-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCIN | scinderin |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLN | sarcolipin |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM132A | transmembrane protein 132A |
| TXK | TXK tyrosine kinase |
| TXLNG | taxilin gamma |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| YOD1 | YOD1 deubiquitinase |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF175 | zinc finger protein 175 |
| ZNF225 | zinc finger protein 225 |
| ZNF230 | zinc finger protein 230 |
| ZNF415 | zinc finger protein 415 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF711 | zinc finger protein 711 |
| ZNF8 | zinc finger protein 8 |
