| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the aztreonam-5535 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ADRA1D | adrenoceptor alpha 1D |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| APOE | apolipoprotein E |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CADM3 | cell adhesion molecule 3 |
| CALCR | calcitonin receptor |
| CASS4 | Cas scaffolding protein family member 4 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDHR2 | cadherin-related family member 2 |
| CDK10 | cyclin-dependent kinase 10 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COL1A1 | collagen, type I, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DST | dystonin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ESR1 | estrogen receptor 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FMO5 | flavin containing monooxygenase 5 |
| FRZB | frizzled-related protein |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR1 | G protein-coupled receptor 1 |
| HAMP | hepcidin antimicrobial peptide |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXA10 | homeobox A10 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IPO5 | importin 5 |
| IRS2 | insulin receptor substrate 2 |
| KLF12 | Kruppel-like factor 12 |
| KRT17 | keratin 17, type I |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MCAM | melanoma cell adhesion molecule |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MX2 | MX dynamin-like GTPase 2 |
| NAG18 | NAG18 mRNA |
| NF1 | neurofibromin 1 |
| NNAT | neuronatin |
| NPTX2 | neuronal pentraxin II |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRIP3 | nuclear receptor interacting protein 3 |
| NUP88 | nucleoporin 88kDa |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 |
| PDE10A | phosphodiesterase 10A |
| PDLIM5 | PDZ and LIM domain 5 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POU4F2 | POU class 4 homeobox 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRKX | protein kinase, X-linked |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RORC | RAR-related orphan receptor C |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH2D1A | SH2 domain containing 1A |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPARCL1 | SPARC-like 1 (hevin) |
| STK17A | serine/threonine kinase 17a |
| STX7 | syntaxin 7 |
| TBX2 | T-box 2 |
| TGM2 | transglutaminase 2 |
| TLR1 | toll-like receptor 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRD | T cell receptor delta locus |
| UNC119 | unc-119 homolog (C. elegans) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF589 | zinc finger protein 589 |
| ZNF79 | zinc finger protein 79 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BBC3 | BCL2 binding component 3 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CCNL2 | cyclin L2 |
| CCNO | cyclin O |
| CD83 | CD83 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPO | centromere protein O |
| CES3 | carboxylesterase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| ELMO3 | engulfment and cell motility 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIFAP3 | kinesin-associated protein 3 |
| LAMA3 | laminin, alpha 3 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MED24 | mediator complex subunit 24 |
| MGC12488 | |
| MTMR11 | myotubularin related protein 11 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDE1 | nudE neurodevelopment protein 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRX1 | NLR family member X1 |
| NOL10 | nucleolar protein 10 |
| OTUD3 | OTU deubiquitinase 3 |
| PLA2G10 | phospholipase A2, group X |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTK6 | protein tyrosine kinase 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| RNF43 | ring finger protein 43 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAIP | TRAF interacting protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN1 | tetraspanin 1 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| WDR19 | WD repeat domain 19 |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF586 | zinc finger protein 586 |
