b cell receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. (Gene Ontology, GO_0019815)
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Genes

255 proteins co-occuring with the b cell receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD79A CD79a molecule, immunoglobulin-associated alpha 2.45712
CD79B CD79b molecule, immunoglobulin-associated beta 2.10493
CD5 CD5 molecule 2.00263
CD19 CD19 molecule 1.97415
BCR breakpoint cluster region 1.91048
CD40 CD40 molecule, TNF receptor superfamily member 5 1.65453
CD22 CD22 molecule 1.55027
CD38 CD38 molecule 1.4429
CXCL9 chemokine (C-X-C motif) ligand 9 1.31843
IL4 interleukin 4 1.28783
CD72 CD72 molecule 1.28676
CD40LG CD40 ligand 1.24445
LYN LYN proto-oncogene, Src family tyrosine kinase 1.2262
CD4 CD4 molecule 1.17773
SYK spleen tyrosine kinase 1.09238
CRNN cornulin 1.0418
CD27 CD27 molecule 1.01883
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.983906
PAX5 paired box 5 0.959748
AICDA activation-induced cytidine deaminase 0.927483
IGHV4-39 immunoglobulin heavy variable 4-39 0.910182
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.864447
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.846073
IL2 interleukin 2 0.838269
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.830466
THY1 Thy-1 cell surface antigen 0.824041
BTK Bruton agammaglobulinemia tyrosine kinase 0.813487
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.794229
IL7 interleukin 7 0.778212
CCND1 cyclin D1 0.757707
PRDM1 PR domain containing 1, with ZNF domain 0.750904
IL5 interleukin 5 0.734666
PREB prolactin regulatory element binding 0.721242
IGHV5-51 immunoglobulin heavy variable 5-51 0.697344
CD69 CD69 molecule 0.692078
IGH immunoglobulin heavy locus 0.690326
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.676368
CD8BP CD8b molecule pseudogene 0.662503
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.662503
BLNK B-cell linker 0.640573
IGHV1-2 immunoglobulin heavy variable 1-2 0.630318
CD24 CD24 molecule 0.626909
TGFB1 transforming growth factor, beta 1 0.620529
CD81 CD81 molecule 0.616709
PTPRC protein tyrosine phosphatase, receptor type, C 0.60444
C4B complement component 4B (Chido blood group) 0.602331
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 0.58134
CD180 CD180 molecule 0.579669
AKAP17A A kinase (PRKA) anchor protein 17A 0.578833
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.572994
PAX2 paired box 2 0.554732
CD37 CD37 molecule 0.552251
GPR176 G protein-coupled receptor 176 0.54771
CD58 CD58 molecule 0.539883
BLK BLK proto-oncogene, Src family tyrosine kinase 0.536183
TRAC T cell receptor alpha constant 0.535361
SIGLEC10 sialic acid binding Ig-like lectin 10 0.533309
FCRL5 Fc receptor-like 5 0.523476
IPP intracisternal A particle-promoted polypeptide 0.523067
SLA Src-like-adaptor 0.514493
MEOX1 mesenchyme homeobox 1 0.505131
FYN FYN proto-oncogene, Src family tyrosine kinase 0.501476
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 0.500258
TFRC transferrin receptor 0.497826
STAP2 signal transducing adaptor family member 2 0.485693
ADAMDEC1 ADAM-like, decysin 1 0.482467
CCDC112 coiled-coil domain containing 112 0.481258
EBF1 early B-cell factor 1 0.462798
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 0.459203
CCL25 chemokine (C-C motif) ligand 25 0.45004
POU2AF1 POU class 2 associating factor 1 0.448848
LPO lactoperoxidase 0.447656
LYZ lysozyme 0.444482
CT45A1 cancer/testis antigen family 45, member A1 0.441708
IGHV3-9 immunoglobulin heavy variable 3-9 0.437751
RAG2 recombination activating gene 2 0.43696
C8G complement component 8, gamma polypeptide 0.436565
IGLV7-43 immunoglobulin lambda variable 7-43 0.432224
CD9 CD9 molecule 0.431041
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.42396
CD34 CD34 molecule 0.421212
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.412601
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.409479
TPT1 tumor protein, translationally-controlled 1 0.398587
IRF4 interferon regulatory factor 4 0.397423
IGHV4-34 immunoglobulin heavy variable 4-34 0.395098
ICAM1 intercellular adhesion molecule 1 0.386208
NPB neuropeptide B 0.378122
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.369684
CD2 CD2 molecule 0.363185
LCK LCK proto-oncogene, Src family tyrosine kinase 0.360515
ICOS inducible T-cell co-stimulator 0.357467
ZDHHC23 zinc finger, DHHC-type containing 23 0.347208
B2M beta-2-microglobulin 0.335487
IL1A interleukin 1, alpha 0.333979
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.333225
TLR9 toll-like receptor 9 0.332472
XBP1 X-box binding protein 1 0.331719
DNTT DNA nucleotidylexotransferase 0.329461
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.324201
HLA-B major histocompatibility complex, class I, B 0.32195
SPN sialophorin 0.316334
IL13 interleukin 13 0.315586
TREML1 triggering receptor expressed on myeloid cells-like 1 0.313344
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.307377
BCL6 B-cell CLL/lymphoma 6 0.306632
OAT ornithine aminotransferase 0.297713
EPX eosinophil peroxidase 0.296972
CD70 CD70 molecule 0.292897
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.290308
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.289938
TNP1 transition protein 1 (during histone to protamine replacement) 0.289199
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.282926
BCAP29 B-cell receptor-associated protein 29 0.27998
CCND2 cyclin D2 0.279245
C3 complement component 3 0.276671
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.272267
CHL1 cell adhesion molecule L1-like 0.26312
CD44 CD44 molecule (Indian blood group) 0.258745
ALB albumin 0.257289
ZFP36L1 ZFP36 ring finger protein-like 1 0.256925
B3GAT1 beta-1,3-glucuronyltransferase 1 0.25547
ZBTB48 zinc finger and BTB domain containing 48 0.25438
PRKCH protein kinase C, eta 0.251114
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.248578
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.246407
LATS1 large tumor suppressor kinase 1 0.238837
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.237401
SELL selectin L 0.235607
C1GALT1C1 C1GALT1-specific chaperone 1 0.232744
KRTAP1-3 keratin associated protein 1-3 0.229532
CD86 CD86 molecule 0.218914
FASLG Fas ligand (TNF superfamily, member 6) 0.211933
CD93 CD93 molecule 0.21124
RNASE3 ribonuclease, RNase A family, 3 0.207794
FGR FGR proto-oncogene, Src family tyrosine kinase 0.205399
EGR1 early growth response 1 0.203361
FLT3 fms-related tyrosine kinase 3 0.203022
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.198991
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.1921
MRO maestro 0.191456
KRTAP1-1 keratin associated protein 1-1 0.191456
CD6 CD6 molecule 0.190814
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.18702
CCL21 chemokine (C-C motif) ligand 21 0.186708
KRT84 keratin 84, type II 0.185469
CCL19 chemokine (C-C motif) ligand 19 0.18516
SPPL2A signal peptide peptidase like 2A 0.181524
CD7 CD7 molecule 0.179167
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.176305
ITPKB inositol-trisphosphate 3-kinase B 0.174361
IFNA1 interferon, alpha 1 0.173273
PHAX phosphorylated adaptor for RNA export 0.173003
IL10 interleukin 10 0.170114
IL27RA interleukin 27 receptor, alpha 0.169604
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.169099
IL6 interleukin 6 0.167366
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.166405
CD276 CD276 molecule 0.166405
CUL3 cullin 3 0.165932
NUB1 negative regulator of ubiquitin-like proteins 1 0.164542
BCL2L1 BCL2-like 1 0.162117
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.161484
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.161484
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.161068
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.160658
MLN motilin 0.137318
CD1E CD1e molecule 0.136887
CSF3 colony stimulating factor 3 (granulocyte) 0.135387
TLR1 toll-like receptor 1 0.133752
CLC Charcot-Leyden crystal galectin 0.131576
HDX highly divergent homeobox 0.130751
PLVAP plasmalemma vesicle associated protein 0.130023
CD63 CD63 molecule 0.129494
IL33 interleukin 33 0.129305
C5AR1 complement component 5a receptor 1 0.129275
ADORA3 adenosine A3 receptor 0.128452
STX1B syntaxin 1B 0.128452
CMA1 chymase 1, mast cell 0.128079
IL21 interleukin 21 0.127355
RGS1 regulator of G-protein signaling 1 0.126672
TRIAP1 TP53 regulated inhibitor of apoptosis 1 0.126609
CCL3 chemokine (C-C motif) ligand 3 0.125031
NPTN neuroplastin 0.124427
CCL2 chemokine (C-C motif) ligand 2 0.123321
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.123188
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.122695
CD8B CD8b molecule 0.122625
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.122556
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.122379
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.12229
MERTK MER proto-oncogene, tyrosine kinase 0.122038
SEPT4 septin 4 0.121817
PRMT2 protein arginine methyltransferase 2 0.121594
MTDH metadherin 0.12129
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.120959
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.120859
HSPE1 heat shock 10kDa protein 1 0.119334
SLURP1 secreted LY6/PLAUR domain containing 1 0.119201
CCL11 chemokine (C-C motif) ligand 11 0.119044
DCT dopachrome tautomerase 0.118955
CXCL12 chemokine (C-X-C motif) ligand 12 0.118818
BCAP31 B-cell receptor-associated protein 31 0.118144
LTA lymphotoxin alpha 0.117879
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.116883
CD209 CD209 molecule 0.116728
CXCR3 chemokine (C-X-C motif) receptor 3 0.116676
TMEM11 transmembrane protein 11 0.116598
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.116572
CD1C CD1c molecule 0.116175
CCNG2 cyclin G2 0.115933
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.11566
CD33 CD33 molecule 0.114958
RXRA retinoid X receptor, alpha 0.1149
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.114583
BET1 Bet1 golgi vesicular membrane trafficking protein 0.114377
CFP complement factor properdin 0.113809
SPAG9 sperm associated antigen 9 0.113225
PGM3 phosphoglucomutase 3 0.112877
ALPPL2 alkaline phosphatase, placental-like 2 0.112814
ALPL alkaline phosphatase, liver/bone/kidney 0.112782
ALPP alkaline phosphatase, placental 0.11275
CCR2 chemokine (C-C motif) receptor 2 0.112525
CCR3 chemokine (C-C motif) receptor 3 0.112168
DUSP5 dual specificity phosphatase 5 0.111702
PHYH phytanoyl-CoA 2-hydroxylase 0.111636
SELENBP1 selenium binding protein 1 0.111535
TNF tumor necrosis factor 0.111467
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.110918
TMPO thymopoietin 0.110883
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.110356
MRC1 mannose receptor, C type 1 0.11032
CD1D CD1d molecule 0.11014
CNTF ciliary neurotrophic factor 0.109997
CD8A CD8a molecule 0.109997
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.109889
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.109449
HM13 histocompatibility (minor) 13 0.109266
MEF2C myocyte enhancer factor 2C 0.109116
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.108356
ICAM3 intercellular adhesion molecule 3 0.108125
TCL1A T-cell leukemia/lymphoma 1A 0.108086
HLA-DMA major histocompatibility complex, class II, DM alpha 0.108009
POLM polymerase (DNA directed), mu 0.10797
HDAC4 histone deacetylase 4 0.107535
HOPX HOP homeobox 0.107535
BCL2 B-cell CLL/lymphoma 2 0.107535
ITGB7 integrin, beta 7 0.107496
CCNG1 cyclin G1 0.107338
GCLC glutamate-cysteine ligase, catalytic subunit 0.107136
DCXR dicarbonyl/L-xylulose reductase 0.106933
UNK unkempt family zinc finger 0.10636
TRIM37 tripartite motif containing 37 0.106029
VCAM1 vascular cell adhesion molecule 1 0.10586
IGBP1 immunoglobulin (CD79A) binding protein 1 0.105775