bacitracin-3109 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bacitracin-3109 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ALK anaplastic lymphoma receptor tyrosine kinase
ARID1A AT rich interactive domain 1A (SWI-like)
ATN1 atrophin 1
ATP13A2 ATPase type 13A2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C17ORF80 chromosome 17 open reading frame 80
C2ORF54 chromosome 2 open reading frame 54
C7ORF69 chromosome 7 open reading frame 69
CD47 CD47 molecule
CDK10 cyclin-dependent kinase 10
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
COBLL1 cordon-bleu WH2 repeat protein-like 1
COPE coatomer protein complex, subunit epsilon
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPM carboxypeptidase M
CTNNBIP1 catenin, beta interacting protein 1
DDN dendrin
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERC2-IT1 ERC2 intronic transcript 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXG1 forkhead box G1
FSHB follicle stimulating hormone, beta polypeptide
FZD4 frizzled class receptor 4
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAREM GRB2 associated, regulator of MAPK1
GLG1 golgi glycoprotein 1
GPR15 G protein-coupled receptor 15
GPR153 G protein-coupled receptor 153
GPR182 G protein-coupled receptor 182
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRWD1 glutamate-rich WD repeat containing 1
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12RB1 interleukin 12 receptor, beta 1
IL36R interleukin 36 receptor
ITPKA inositol-trisphosphate 3-kinase A
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KRT86 keratin 86, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC284244 uncharacterized LOC284244
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MEG3 maternally expressed 3 (non-protein coding)
MMP25 matrix metallopeptidase 25
MPDZ multiple PDZ domain protein
MUC8 mucin 8
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
PCIF1 PDX1 C-terminal inhibiting factor 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDPN podoplanin
PER3 period circadian clock 3
PEX1 peroxisomal biogenesis factor 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMEL premelanosome protein
PNPLA4 patatin-like phospholipase domain containing 4
PORCN porcupine homolog (Drosophila)
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRLH prolactin releasing hormone
PTGDS prostaglandin D2 synthase 21kDa (brain)
QTRT1 queuine tRNA-ribosyltransferase 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASL11B RAS-like, family 11, member B
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RET ret proto-oncogene
RETN resistin
RIF1 replication timing regulatory factor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SFTPB surfactant protein B
SLAMF8 SLAM family member 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SORBS3 sorbin and SH3 domain containing 3
SPTBN1 spectrin, beta, non-erythrocytic 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAOK2 TAO kinase 2
TFR2 transferrin receptor 2
TMEM63A transmembrane protein 63A
TPMT thiopurine S-methyltransferase
TSGA10 testis specific, 10
UMPS uridine monophosphate synthetase
UNC93B1 unc-93 homolog B1 (C. elegans)
ZER1 zyg-11 related, cell cycle regulator
ZFHX2 zinc finger homeobox 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACP6 acid phosphatase 6, lysophosphatidic
ACPP acid phosphatase, prostate
ADAM15 ADAM metallopeptidase domain 15
ARMC6 armadillo repeat containing 6
AXIN1 axin 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BEND5 BEN domain containing 5
C1ORF105 chromosome 1 open reading frame 105
C6ORF47 chromosome 6 open reading frame 47
CD37 CD37 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CENPO centromere protein O
CIDEC cell death-inducing DFFA-like effector c
CLCN5 chloride channel, voltage-sensitive 5
CLDN7 claudin 7
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND1C DENN/MADD domain containing 1C
DGKG diacylglycerol kinase, gamma 90kDa
ELP6 elongator acetyltransferase complex subunit 6
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXL6 F-box and leucine-rich repeat protein 6
FGF9 fibroblast growth factor 9
FZD3 frizzled class receptor 3
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRIP2 glutamate receptor interacting protein 2
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM3 interferon induced transmembrane protein 3
IL2 interleukin 2
IL3RA interleukin 3 receptor, alpha (low affinity)
INCENP inner centromere protein antigens 135/155kDa
KIF1B kinesin family member 1B
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LATS1 large tumor suppressor kinase 1
LINC00216 long intergenic non-protein coding RNA 216
LOC100286895 cell division cycle 27 homolog pseudogene
LOC390998 ribosomal protein L10 pseudogene
LTBP3 latent transforming growth factor beta binding protein 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MX1 MX dynamin-like GTPase 1
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NIPAL2 NIPA-like domain containing 2
NLK nemo-like kinase
NT5M 5',3'-nucleotidase, mitochondrial
OCEL1 occludin/ELL domain containing 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRAF2 PRA1 domain family, member 2
PSKH1 protein serine kinase H1
QSER1 glutamine and serine rich 1
RAB3D RAB3D, member RAS oncogene family
RANBP17 RAN binding protein 17
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RND1 Rho family GTPase 1
SCGB2A2 secretoglobin, family 2A, member 2
SIRT6 sirtuin 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35F6 solute carrier family 35, member F6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRYD7 SPRY domain containing 7
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAS2R4 taste receptor, type 2, member 4
TIMP2 TIMP metallopeptidase inhibitor 2
TLR6 toll-like receptor 6
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRIM45 tripartite motif containing 45
TUBA4B tubulin, alpha 4b
TWSG1 twisted gastrulation BMP signaling modulator 1
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VSIG10 V-set and immunoglobulin domain containing 10
XAB2 XPA binding protein 2
ZHX2 zinc fingers and homeoboxes 2
ZNF324 zinc finger protein 324
ZNF778 zinc finger protein 778
ZNF787 zinc finger protein 787
ZNF8 zinc finger protein 8
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862