| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the bacitracin-6488 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| AASS | aminoadipate-semialdehyde synthase |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AK1 | adenylate kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| APOC1 | apolipoprotein C-I |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| AVPR1B | arginine vasopressin receptor 1B |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| CALB2 | calbindin 2 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC40 | coiled-coil domain containing 40 |
| CD34 | CD34 molecule |
| CD58 | CD58 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CNTN1 | contactin 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DENND1C | DENN/MADD domain containing 1C |
| DPP4 | dipeptidyl-peptidase 4 |
| EN1 | engrailed homeobox 1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF13 | fibroblast growth factor 13 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNRHR | gonadotropin-releasing hormone receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HFE | hemochromatosis |
| HPX | hemopexin |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IL11 | interleukin 11 |
| IPO8 | importin 8 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| LMF2 | lipase maturation factor 2 |
| MAGEA6 | melanoma antigen family A6 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MTA1 | metastasis associated 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYCNOS | MYCN opposite strand |
| N4BP1 | NEDD4 binding protein 1 |
| NF1 | neurofibromin 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PALM | paralemmin |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKD3 | protein kinase D3 |
| PRM1 | protamine 1 |
| PRPH | peripherin |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB11B | RAB11B, member RAS oncogene family |
| RASIP1 | Ras interacting protein 1 |
| RELN | reelin |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TGM2 | transglutaminase 2 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP63 | tumor protein p63 |
| TPMT | thiopurine S-methyltransferase |
| TRA | T cell receptor alpha locus |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIM2 | tripartite motif containing 2 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TXNRD2 | thioredoxin reductase 2 |
| UCN | urocortin |
| VAMP4 | vesicle-associated membrane protein 4 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACVR2A | activin A receptor, type IIA |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BAG4 | BCL2-associated athanogene 4 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC9 | coiled-coil domain containing 9 |
| CCNT1 | cyclin T1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CEL | carboxyl ester lipase |
| CLDND1 | claudin domain containing 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ECI1 | enoyl-CoA delta isomerase 1 |
| EDAR | ectodysplasin A receptor |
| EDC3 | enhancer of mRNA decapping 3 |
| EMID1 | EMI domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM110B | family with sequence similarity 110, member B |
| FAM120C | family with sequence similarity 120C |
| FAM222B | family with sequence similarity 222, member B |
| FGL1 | fibrinogen-like 1 |
| FILIP1L | filamin A interacting protein 1-like |
| GLI3 | GLI family zinc finger 3 |
| GPR3 | G protein-coupled receptor 3 |
| GSTP1 | glutathione S-transferase pi 1 |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL4R | interleukin 4 receptor |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT20 | keratin 20, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MXD3 | MAX dimerization protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDH12 | protocadherin 12 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFD | platelet derived growth factor D |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLD2 | phospholipase D2 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF122 | ring finger protein 122 |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAGLN | transgelin |
| TCTA | T-cell leukemia translocation altered |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFF2 | trefoil factor 2 |
| TMEM57 | transmembrane protein 57 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| TRIM25 | tripartite motif containing 25 |
| TSPAN2 | tetraspanin 2 |
| TWF2 | twinfilin actin binding protein 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF136 | zinc finger protein 136 |
| ZNF428 | zinc finger protein 428 |
| ZNF665 | zinc finger protein 665 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |