bacitracin-6488 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bacitracin-6488 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
AASS aminoadipate-semialdehyde synthase
ADRBK1 adrenergic, beta, receptor kinase 1
AK1 adenylate kinase 1
ALS2CL ALS2 C-terminal like
APOC1 apolipoprotein C-I
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AVPR1B arginine vasopressin receptor 1B
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CALB2 calbindin 2
CARD9 caspase recruitment domain family, member 9
CCDC40 coiled-coil domain containing 40
CD34 CD34 molecule
CD58 CD58 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CNTN1 contactin 1
CSPP1 centrosome and spindle pole associated protein 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DENND1C DENN/MADD domain containing 1C
DPP4 dipeptidyl-peptidase 4
EN1 engrailed homeobox 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF13 fibroblast growth factor 13
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GFI1 growth factor independent 1 transcription repressor
GNRHR gonadotropin-releasing hormone receptor
GSTTP1 glutathione S-transferase theta pseudogene 1
HFE hemochromatosis
HPX hemopexin
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL11 interleukin 11
IPO8 importin 8
ISG20 interferon stimulated exonuclease gene 20kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LMF2 lipase maturation factor 2
MAGEA6 melanoma antigen family A6
MAP2K2 mitogen-activated protein kinase kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MPL MPL proto-oncogene, thrombopoietin receptor
MTA1 metastasis associated 1
MTRF1L mitochondrial translational release factor 1-like
MYCNOS MYCN opposite strand
N4BP1 NEDD4 binding protein 1
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PALM paralemmin
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PLCD1 phospholipase C, delta 1
PPAP2B phosphatidic acid phosphatase type 2B
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKD3 protein kinase D3
PRM1 protamine 1
PRPH peripherin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRS protein tyrosine phosphatase, receptor type, S
RAB11B RAB11B, member RAS oncogene family
RASIP1 Ras interacting protein 1
RELN reelin
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN11A sodium channel, voltage gated, type XI alpha subunit
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNED1 sushi, nidogen and EGF-like domains 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SRSF1 serine/arginine-rich splicing factor 1
STOML1 stomatin (EPB72)-like 1
SUGCT succinyl-CoA:glutarate-CoA transferase
TBL1Y transducin (beta)-like 1, Y-linked
TGM2 transglutaminase 2
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP63 tumor protein p63
TPMT thiopurine S-methyltransferase
TRA T cell receptor alpha locus
TRAK1 trafficking protein, kinesin binding 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM2 tripartite motif containing 2
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TTC38 tetratricopeptide repeat domain 38
TXNRD2 thioredoxin reductase 2
UCN urocortin
VAMP4 vesicle-associated membrane protein 4
VIPR2 vasoactive intestinal peptide receptor 2
WFDC2 WAP four-disulfide core domain 2
WIPF1 WAS/WASL interacting protein family, member 1
ZER1 zyg-11 related, cell cycle regulator
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ACVR2A activin A receptor, type IIA
ADGRG2 adhesion G protein-coupled receptor G2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASAP1-IT1 ASAP1 intronic transcript 1
BAG4 BCL2-associated athanogene 4
C11ORF68 chromosome 11 open reading frame 68
C2ORF27A chromosome 2 open reading frame 27A
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC9 coiled-coil domain containing 9
CCNT1 cyclin T1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEL carboxyl ester lipase
CLDND1 claudin domain containing 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
ECHDC2 enoyl CoA hydratase domain containing 2
ECI1 enoyl-CoA delta isomerase 1
EDAR ectodysplasin A receptor
EDC3 enhancer of mRNA decapping 3
EMID1 EMI domain containing 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM222B family with sequence similarity 222, member B
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
GLI3 GLI family zinc finger 3
GPR3 G protein-coupled receptor 3
GSTP1 glutathione S-transferase pi 1
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IL4R interleukin 4 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLK5 kallikrein-related peptidase 5
KRT20 keratin 20, type I
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC61 leucine rich repeat containing 61
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBTPS2 membrane-bound transcription factor peptidase, site 2
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
PAIP2B poly(A) binding protein interacting protein 2B
PARD6A par-6 family cell polarity regulator alpha
PCDH12 protocadherin 12
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFD platelet derived growth factor D
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD2 phospholipase D2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF122 ring finger protein 122
RPP14 ribonuclease P/MRP 14kDa subunit
SAYSD1 SAYSVFN motif domain containing 1
SCAMP3 secretory carrier membrane protein 3
SCGB2A2 secretoglobin, family 2A, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPINK5 serine peptidase inhibitor, Kazal type 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAGLN transgelin
TCTA T-cell leukemia translocation altered
TET3 tet methylcytosine dioxygenase 3
TFF2 trefoil factor 2
TMEM57 transmembrane protein 57
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
TSPAN2 tetraspanin 2
TWF2 twinfilin actin binding protein 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF136 zinc finger protein 136
ZNF428 zinc finger protein 428
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675
ZSCAN31 zinc finger and SCAN domain containing 31