| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the bacitracin-7448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ARMC4 | armadillo repeat containing 4 |
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| AURKA | aurora kinase A |
| BEX1 | brain expressed, X-linked 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC9 | coiled-coil domain containing 9 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP295 | centrosomal protein 295kDa |
| CIC | capicua transcriptional repressor |
| CLDN17 | claudin 17 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTH | cystathionine gamma-lyase |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DST | dystonin |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EHD1 | EH-domain containing 1 |
| EPS8L1 | EPS8-like 1 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EVPL | envoplakin |
| EXPH5 | exophilin 5 |
| FAM134B | family with sequence similarity 134, member B |
| FAM188A | family with sequence similarity 188, member A |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FHL1 | four and a half LIM domains 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GSPT1 | G1 to S phase transition 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXB2 | homeobox B2 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IRS2 | insulin receptor substrate 2 |
| KHSRP | KH-type splicing regulatory protein |
| LEPR | leptin receptor |
| LMAN1 | lectin, mannose-binding, 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MYOF | myoferlin |
| NAAA | N-acylethanolamine acid amidase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PLLP | plasmolipin |
| PLXNB1 | plexin B1 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCAN3 | RCAN family member 3 |
| REEP1 | receptor accessory protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS4 | regulator of G-protein signaling 4 |
| RNF122 | ring finger protein 122 |
| RNFT2 | ring finger protein, transmembrane 2 |
| SAA4 | serum amyloid A4, constitutive |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPN | sialophorin |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAT5B | signal transducer and activator of transcription 5B |
| STIM1 | stromal interaction molecule 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAOK1 | TAO kinase 1 |
| TBX19 | T-box 19 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBD | thrombomodulin |
| THBS3 | thrombospondin 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| UNC5B | unc-5 homolog B (C. elegans) |
| USP19 | ubiquitin specific peptidase 19 |
| VCX2 | variable charge, X-linked 2 |
| VEGFB | vascular endothelial growth factor B |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XDH | xanthine dehydrogenase |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF211 | zinc finger protein 211 |
| ZNF34 | zinc finger protein 34 |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAGE | B melanoma antigen |
| BAK1 | BCL2-antagonist/killer 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BRD9 | bromodomain containing 9 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CBX8 | chromobox homolog 8 |
| CEP131 | centrosomal protein 131kDa |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| COPS7B | COP9 signalosome subunit 7B |
| COQ6 | coenzyme Q6 monooxygenase |
| CPTP | ceramide-1-phosphate transfer protein |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOCK1 | dedicator of cytokinesis 1 |
| EAF2 | ELL associated factor 2 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA3 | ephrin-A3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXO31 | F-box protein 31 |
| FKBP5 | FK506 binding protein 5 |
| FOXC1 | forkhead box C1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD2 | frizzled class receptor 2 |
| GPR27 | G protein-coupled receptor 27 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4F | histone cluster 1, H4f |
| HOXA5 | homeobox A5 |
| HPSE | heparanase |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RA | interleukin 17 receptor A |
| IRF9 | interferon regulatory factor 9 |
| KDM7A | lysine (K)-specific demethylase 7A |
| LMNB1 | lamin B1 |
| LRRC20 | leucine rich repeat containing 20 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCOLN3 | mucolipin 3 |
| METTL16 | methyltransferase like 16 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NBEAL2 | neurobeachin-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEO1 | neogenin 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RWDD3 | RWD domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC4 | tetratricopeptide repeat domain 4 |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| XPA | xeroderma pigmentosum, complementation group A |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF692 | zinc finger protein 692 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |