| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the baclofen-2036 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| AURKC | aurora kinase C |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP15 | bone morphogenetic protein 15 |
| BSPRY | B-box and SPRY domain containing |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CADM3 | cell adhesion molecule 3 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD22 | CD22 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL4A2 | collagen, type IV, alpha 2 |
| COLEC12 | collectin sub-family member 12 |
| CREM | cAMP responsive element modulator |
| CS | citrate synthase |
| DGCR8 | DGCR8 microprocessor complex subunit |
| EFS | embryonal Fyn-associated substrate |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| ELMO2 | engulfment and cell motility 2 |
| ENOSF1 | enolase superfamily member 1 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM153A | family with sequence similarity 153, member A |
| FAS | Fas cell surface death receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| HFE | hemochromatosis |
| IGF1R | insulin-like growth factor 1 receptor |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL5RA | interleukin 5 receptor, alpha |
| IMPACT | impact RWD domain protein |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| LACTB2 | lactamase, beta 2 |
| LAMA4 | laminin, alpha 4 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LTB4R | leukotriene B4 receptor |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MST1 | macrophage stimulating 1 |
| MTAP | methylthioadenosine phosphorylase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO9B | myosin IXB |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| OPRL1 | opiate receptor-like 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 |
| PAPPA2 | pappalysin 2 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PRDM11 | PR domain containing 11 |
| PRSS50 | protease, serine, 50 |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF216 | ring finger protein 216 |
| RPS3A | ribosomal protein S3A |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SPN | sialophorin |
| SPON1 | spondin 1, extracellular matrix protein |
| STAC | SH3 and cysteine rich domain |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TPM3 | tropomyosin 3 |
| TRIM48 | tripartite motif containing 48 |
| TYR | tyrosinase |
| USP2 | ubiquitin specific peptidase 2 |
| USP29 | ubiquitin specific peptidase 29 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF614 | zinc finger protein 614 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ABHD3 | abhydrolase domain containing 3 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ASNSD1 | asparagine synthetase domain containing 1 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCAS2 | breast carcinoma amplified sequence 2 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CCND3 | cyclin D3 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CETN2 | centrin, EF-hand protein, 2 |
| CFL1 | cofilin 1 (non-muscle) |
| CMC2 | C-x(9)-C motif containing 2 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CTSC | cathepsin C |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DLD | dihydrolipoamide dehydrogenase |
| DOCK2 | dedicator of cytokinesis 2 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FKBP3 | FK506 binding protein 3, 25kDa |
| GMPR2 | guanosine monophosphate reductase 2 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HDAC1 | histone deacetylase 1 |
| HIST1H4C | histone cluster 1, H4c |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| IRF8 | interferon regulatory factor 8 |
| LAGE3 | L antigen family, member 3 |
| LOC100272216 | uncharacterized LOC100272216 |
| LSM1 | LSM1, U6 small nuclear RNA associated |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MRPL48 | mitochondrial ribosomal protein L48 |
| MTCH1 | mitochondrial carrier 1 |
| MTPAP | mitochondrial poly(A) polymerase |
| NDEL1 | nudE neurodevelopment protein 1-like 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa |
| NIT2 | nitrilase family, member 2 |
| NMI | N-myc (and STAT) interactor |
| NUCB2 | nucleobindin 2 |
| NUCLEOLIN | nucleolin multifunctional protein |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OLA1 | Obg-like ATPase 1 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRR13 | proline rich 13 |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| PTDSS1 | phosphatidylserine synthase 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| REPIN1 | replication initiator 1 |
| REXO2 | RNA exonuclease 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF187 | ring finger protein 187 |
| RPL34 | ribosomal protein L34 |
| RPL35 | ribosomal protein L35 |
| RPL36AL | ribosomal protein L36a-like |
| RPS27A | ribosomal protein S27a |
| RPS27L | ribosomal protein S27-like |
| RPS5 | ribosomal protein S5 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SAR1B | secretion associated, Ras related GTPase 1B |
| SCAND1 | SCAN domain containing 1 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| SEH1L | SEH1-like (S. cerevisiae) |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNX5 | sorting nexin 5 |
| SOD1 | superoxide dismutase 1, soluble |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 |
| TSPO | translocator protein (18kDa) |
| TSSC1 | tumor suppressing subtransferable candidate 1 |
| TTC1 | tetratricopeptide repeat domain 1 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBG1 | tubulin, gamma 1 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| UROS | uroporphyrinogen III synthase |
| USP47 | ubiquitin specific peptidase 47 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VAMP8 | vesicle-associated membrane protein 8 |
| WDR82 | WD repeat domain 82 |
| ZXDC | ZXD family zinc finger C |
