| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the baclofen-6313 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABHD2 | abhydrolase domain containing 2 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ATN1 | atrophin 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CD52 | CD52 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH8 | cadherin 8, type 2 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC11A | C-type lectin domain family 11, member A |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COL10A1 | collagen, type X, alpha 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCTN1 | dynactin 1 |
| EFNA3 | ephrin-A3 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ESR1 | estrogen receptor 1 |
| EXOSC1 | exosome component 1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLRX3 | glutaredoxin 3 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| HABP4 | hyaluronan binding protein 4 |
| HIST1H4D | histone cluster 1, H4d |
| HMG20B | high mobility group 20B |
| INO80B | INO80 complex subunit B |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNV1 | potassium channel, voltage gated modifier subfamily V, member 1 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KIAA1456 | KIAA1456 |
| KIF1A | kinesin family member 1A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL4 | kelch-like family member 4 |
| KYNU | kynureninase |
| LAMB4 | laminin, beta 4 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL3 | lysyl oxidase-like 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAL | mal, T-cell differentiation protein |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| METTL7A | methyltransferase like 7A |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMRN2 | multimerin 2 |
| MPZL2 | myelin protein zero-like 2 |
| MRAS | muscle RAS oncogene homolog |
| MTRF1L | mitochondrial translational release factor 1-like |
| MXD3 | MAX dimerization protein 3 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLXNC1 | plexin C1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PROL1 | proline rich, lacrimal 1 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SNRK | SNF related kinase |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SSH3 | slingshot protein phosphatase 3 |
| SSTR2 | somatostatin receptor 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYK | spleen tyrosine kinase |
| SYNJ2 | synaptojanin 2 |
| TACR1 | tachykinin receptor 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCP10 | t-complex 10 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNIK | TRAF2 and NCK interacting kinase |
| TRABD | TraB domain containing |
| USP19 | ubiquitin specific peptidase 19 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| WWOX | WW domain containing oxidoreductase |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| APIP | APAF1 interacting protein |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BAG4 | BCL2-associated athanogene 4 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CAPN15 | calpain 15 |
| CCDC68 | coiled-coil domain containing 68 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CEP131 | centrosomal protein 131kDa |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPOX | coproporphyrinogen oxidase |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| ECM1 | extracellular matrix protein 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM50B | family with sequence similarity 50, member B |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIRA | histone cell cycle regulator |
| HLX | H2.0-like homeobox |
| HOXC13 | homeobox C13 |
| HSPB8 | heat shock 22kDa protein 8 |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| LBR | lamin B receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAMLD1 | mastermind-like domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCRS1 | microspherule protein 1 |
| MEIS1 | Meis homeobox 1 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MUC3B | mucin 3B, cell surface associated |
| MUC7 | mucin 7, secreted |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1E | myosin IE |
| NADSYN1 | NAD synthetase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NOTCH1 | notch 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEPD | peptidase D |
| PER3 | period circadian clock 3 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLIN3 | perilipin 3 |
| PLSCR4 | phospholipid scramblase 4 |
| POM121 | POM121 transmembrane nucleoporin |
| PRR3 | proline rich 3 |
| PRR7 | proline rich 7 (synaptic) |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RANBP17 | RAN binding protein 17 |
| RARS | arginyl-tRNA synthetase |
| RASA2 | RAS p21 protein activator 2 |
| RNF31 | ring finger protein 31 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SGMS1 | sphingomyelin synthase 1 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPATA2L | spermatogenesis associated 2-like |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM121 | transmembrane protein 121 |
| TMEM156 | transmembrane protein 156 |
| TMEM159 | transmembrane protein 159 |
| TMEM2 | transmembrane protein 2 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TUBA3C | tubulin, alpha 3c |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR5B | WD repeat domain 5B |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF442 | zinc finger protein 442 |
| ZNF552 | zinc finger protein 552 |
| ZNF571 | zinc finger protein 571 |