bad Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description BCL2-associated agonist of cell death|The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 572)
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Genes

60 proteins co-occuring with the biological term bad in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMF Bcl2 modifying factor
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
DUSP1 dual specificity phosphatase 1
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FLT3 fms-related tyrosine kinase 3
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HJURP Holliday junction recognition protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL7R interleukin 7 receptor
IRS1 insulin receptor substrate 1
JUN jun proto-oncogene
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
PEA15 phosphoprotein enriched in astrocytes 15
PRKCB protein kinase C, beta
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PTK2 protein tyrosine kinase 2
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SFN stratifin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
TP53 tumor protein p53
TSC2 tuberous sclerosis 2
URI1 URI1, prefoldin-like chaperone
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta