bambuterol-1582 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bambuterol-1582 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACIN1 apoptotic chromatin condensation inducer 1
ACTN1 actinin, alpha 1
ADGRA2 adhesion G protein-coupled receptor A2
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ATP2A3 ATPase, Ca++ transporting, ubiquitous
C19ORF66 chromosome 19 open reading frame 66
C9ORF156 chromosome 9 open reading frame 156
CBX5 chromobox homolog 5
CCL20 chemokine (C-C motif) ligand 20
CELF2 CUGBP, Elav-like family member 2
CHAF1A chromatin assembly factor 1, subunit A (p150)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYB561 cytochrome b561
DAXX death-domain associated protein
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIDO1 death inducer-obliterator 1
DUS2 dihydrouridine synthase 2
DUSP2 dual specificity phosphatase 2
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EHD1 EH-domain containing 1
ELAC2 elaC ribonuclease Z 2
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM57A family with sequence similarity 57, member A
FANCA Fanconi anemia, complementation group A
FEN1 flap structure-specific endonuclease 1
FMNL1 formin-like 1
FOSL1 FOS-like antigen 1
FRY furry homolog (Drosophila)
GIMAP5 GTPase, IMAP family member 5
GLRX3 glutaredoxin 3
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GOLM1 golgi membrane protein 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSK3A glycogen synthase kinase 3 alpha
GTPBP1 GTP binding protein 1
HCFC1 host cell factor C1
HINT1 histidine triad nucleotide binding protein 1
ICA1 islet cell autoantigen 1, 69kDa
IL1RAP interleukin 1 receptor accessory protein
IL5RA interleukin 5 receptor, alpha
KIF3C kinesin family member 3C
KIFC1 kinesin family member C1
KLF6 Kruppel-like factor 6
KLHDC4 kelch domain containing 4
KRI1 KRI1 homolog (S. cerevisiae)
KRIT1 KRIT1, ankyrin repeat containing
LARP1 La ribonucleoprotein domain family, member 1
LMAN2L lectin, mannose-binding 2-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAP7D3 MAP7 domain containing 3
METRN meteorin, glial cell differentiation regulator
MICALL1 MICAL-like 1
MISP mitotic spindle positioning
MPP1 membrane protein, palmitoylated 1, 55kDa
MXD4 MAX dimerization protein 4
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL10 myosin, light chain 10, regulatory
MYO1C myosin IC
MYO9B myosin IXB
N4BP1 NEDD4 binding protein 1
NCR2 natural cytotoxicity triggering receptor 2
NDRG2 NDRG family member 2
NOP16 NOP16 nucleolar protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PADI4 peptidyl arginine deiminase, type IV
PLEK2 pleckstrin 2
PNO1 partner of NOB1 homolog (S. cerevisiae)
POGLUT1 protein O-glucosyltransferase 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PREP prolyl endopeptidase
PRRC2B proline-rich coiled-coil 2B
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB33B RAB33B, member RAS oncogene family
SEC61B Sec61 beta subunit
SFSWAP splicing factor, suppressor of white-apricot family
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD3 SMAD family member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTB spectrin, beta, erythrocytic
SSH3 slingshot protein phosphatase 3
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TMEM134 transmembrane protein 134
TMEM8A transmembrane protein 8A
TMPRSS15 transmembrane protease, serine 15
TRIL TLR4 interactor with leucine-rich repeats
UMPS uridine monophosphate synthetase
URI1 URI1, prefoldin-like chaperone
USF2 upstream transcription factor 2, c-fos interacting
USP20 ubiquitin specific peptidase 20
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBTB40 zinc finger and BTB domain containing 40
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF408 zinc finger protein 408

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
ACOT9 acyl-CoA thioesterase 9
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ASB8 ankyrin repeat and SOCS box containing 8
ATP11B ATPase, class VI, type 11B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AZI2 5-azacytidine induced 2
B3GNT1
BCL10 B-cell CLL/lymphoma 10
BTNL3 butyrophilin-like 3
C11ORF95 chromosome 11 open reading frame 95
C12ORF29 chromosome 12 open reading frame 29
C16ORF62 chromosome 16 open reading frame 62
C1D C1D nuclear receptor corepressor
CASP8AP2 caspase 8 associated protein 2
CD302 CD302 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CENPQ centromere protein Q
COMMD8 COMM domain containing 8
CPOX coproporphyrinogen oxidase
CRYBG3 beta-gamma crystallin domain containing 3
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DCLRE1A DNA cross-link repair 1A
DENND4A DENN/MADD domain containing 4A
DLD dihydrolipoamide dehydrogenase
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DMTF1 cyclin D binding myb-like transcription factor 1
DPF2 D4, zinc and double PHD fingers family 2
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERBB2IP erbb2 interacting protein
EXOSC9 exosome component 9
FAM179B family with sequence similarity 179, member B
FAM222B family with sequence similarity 222, member B
FAM63A family with sequence similarity 63, member A
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPN3 GPN-loop GTPase 3
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC4 histone deacetylase 4
HRSP12 heat-responsive protein 12
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KAT2A K(lysine) acetyltransferase 2A
LBR lamin B receptor
LRRC37A2 leucine rich repeat containing 37, member A2
LXN latexin
MAEA macrophage erythroblast attacher
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED23 mediator complex subunit 23
MEIS2 Meis homeobox 2
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MNS1 meiosis-specific nuclear structural 1
MOAP1 modulator of apoptosis 1
MPV17 MpV17 mitochondrial inner membrane protein
MTERF3 mitochondrial transcription termination factor 3
MYL12B myosin, light chain 12B, regulatory
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
OGFRL1 opioid growth factor receptor-like 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDHX pyruvate dehydrogenase complex, component X
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTGES2 prostaglandin E synthase 2
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB4B RAB4B, member RAS oncogene family
RARS arginyl-tRNA synthetase
REPIN1 replication initiator 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS10P5 ribosomal protein S10 pseudogene 5
RPS27A ribosomal protein S27a
RRP1 ribosomal RNA processing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RWDD3 RWD domain containing 3
SATB1 SATB homeobox 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC25A40 solute carrier family 25, member 40
SLC30A9 solute carrier family 30 (zinc transporter), member 9
STRA13 stimulated by retinoic acid 13
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM14A transmembrane protein 14A
TMEM186 transmembrane protein 186
TOP2B topoisomerase (DNA) II beta 180kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRHDE thyrotropin-releasing hormone degrading enzyme
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TTC13 tetratricopeptide repeat domain 13
USPL1 ubiquitin specific peptidase like 1
WDR82 WD repeat domain 82
ZNF189 zinc finger protein 189
ZNF430 zinc finger protein 430
ZNF665 zinc finger protein 665