bambuterol-5885 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bambuterol-5885 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADAM22 ADAM metallopeptidase domain 22
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ARTN artemin
BAIAP3 BAI1-associated protein 3
BRS3 bombesin-like receptor 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1RL complement component 1, r subcomponent-like
CACTIN cactin, spliceosome C complex subunit
CCNO cyclin O
CCNT2 cyclin T2
CD82 CD82 molecule
CDC42 cell division cycle 42
CDRT1 CMT1A duplicated region transcript 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CISH cytokine inducible SH2-containing protein
COL21A1 collagen, type XXI, alpha 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
DAPK3 death-associated protein kinase 3
DESI2 desumoylating isopeptidase 2
DGKE diacylglycerol kinase, epsilon 64kDa
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DST dystonin
EGFR epidermal growth factor receptor
FKBP5 FK506 binding protein 5
FMOD fibromodulin
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLP1R glucagon-like peptide 1 receptor
GREM1 gremlin 1, DAN family BMP antagonist
GRM8 glutamate receptor, metabotropic 8
GRTP1 growth hormone regulated TBC protein 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H4D histone cluster 1, H4d
HLA-DOA major histocompatibility complex, class II, DO alpha
HNF4A hepatocyte nuclear factor 4, alpha
HYAL3 hyaluronoglucosaminidase 3
IGHA1 immunoglobulin heavy constant alpha 1
IL36A interleukin 36, alpha
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIAA0930 KIAA0930
KIF1A kinesin family member 1A
KLHL25 kelch-like family member 25
KLHL29 kelch-like family member 29
KRIT1 KRIT1, ankyrin repeat containing
KYNU kynureninase
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LARP7 La ribonucleoprotein domain family, member 7
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7D3 MAP7 domain containing 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MFAP3L microfibrillar-associated protein 3-like
MMRN2 multimerin 2
MOBP myelin-associated oligodendrocyte basic protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NIPAL2 NIPA-like domain containing 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PBX2 pre-B-cell leukemia homeobox 2
PEX5L peroxisomal biogenesis factor 5-like
PLIN2 perilipin 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQBP1 polyglutamine binding protein 1
PSKH1 protein serine kinase H1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB31 RAB31, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RARB retinoic acid receptor, beta
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPP25 ribonuclease P/MRP 25kDa subunit
RTN2 reticulon 2
SCG2 secretogranin II
SCIN scinderin
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TACR1 tachykinin receptor 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TEF thyrotrophic embryonic factor
TLE4 transducin-like enhancer of split 4
TMEM259 transmembrane protein 259
TMEM8B transmembrane protein 8B
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPAN9 tetraspanin 9
TSSK2 testis-specific serine kinase 2
TXNRD3 thioredoxin reductase 3
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WRAP53 WD repeat containing, antisense to TP53
YY1 YY1 transcription factor
ZNF385D zinc finger protein 385D
ZNF93 zinc finger protein 93
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AMBRA1 autophagy/beclin-1 regulator 1
AMDHD2 amidohydrolase domain containing 2
ANKRD40 ankyrin repeat domain 40
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ATP10D ATPase, class V, type 10D
ATP7B ATPase, Cu++ transporting, beta polypeptide
AXIN1 axin 1
BAK1 BCL2-antagonist/killer 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIK BCL2-interacting killer (apoptosis-inducing)
C16ORF45 chromosome 16 open reading frame 45
C1ORF35 chromosome 1 open reading frame 35
CAPN15 calpain 15
CBR4 carbonyl reductase 4
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH7 cadherin 7, type 2
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP69 cilia and flagella associated protein 69
CGREF1 cell growth regulator with EF-hand domain 1
CPA4 carboxypeptidase A4
CXORF56 chromosome X open reading frame 56
ECM1 extracellular matrix protein 1
EFNA3 ephrin-A3
EPPK1 epiplakin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
GALT galactose-1-phosphate uridylyltransferase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GPATCH3 G patch domain containing 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HMG20A high mobility group 20A
HOOK1 hook microtubule-tethering protein 1
HOXA7 homeobox A7
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA1549L KIAA1549-like
KLHL28 kelch-like family member 28
KRT4 keratin 4, type II
LOC730101 uncharacterized LOC730101
LRRC15 leucine rich repeat containing 15
LRRC37A3 leucine rich repeat containing 37, member A3
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTR1 leucine-zipper-like transcription regulator 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAST3 microtubule associated serine/threonine kinase 3
MCTP1 multiple C2 domains, transmembrane 1
MEIS1 Meis homeobox 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTMR12 myotubularin related protein 12
NACA2 nascent polypeptide-associated complex alpha subunit 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
PHLDA3 pleckstrin homology-like domain, family A, member 3
PID1 phosphotyrosine interaction domain containing 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POM121 POM121 transmembrane nucleoporin
PRR3 proline rich 3
PTK6 protein tyrosine kinase 6
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB3A RAB3A, member RAS oncogene family
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF122 ring finger protein 122
ROGDI rogdi homolog (Drosophila)
RPS17P5 ribosomal protein S17 pseudogene 5
SASH1 SAM and SH3 domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETBP1 SET binding protein 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC35G2 solute carrier family 35, member G2
SNUPN snurportin 1
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN3 transgelin 3
TBC1D19 TBC1 domain family, member 19
TMC5 transmembrane channel-like 5
TMC7 transmembrane channel-like 7
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNRC6B trinucleotide repeat containing 6B
TUBG2 tubulin, gamma 2
TWF2 twinfilin actin binding protein 2
TXLNG taxilin gamma
WDR37 WD repeat domain 37
ZNF32 zinc finger protein 32