bambuterol-7239 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bambuterol-7239 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AGMAT agmatine ureohydrolase (agmatinase)
AK2 adenylate kinase 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2L1 BCL2-like 1
BMP2K BMP2 inducible kinase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCRL2 chemokine (C-C motif) receptor-like 2
CDC14B cell division cycle 14B
CEND1 cell cycle exit and neuronal differentiation 1
CHST10 carbohydrate sulfotransferase 10
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CUL9 cullin 9
DGKQ diacylglycerol kinase, theta 110kDa
DIO2 deiodinase, iodothyronine, type II
DOK4 docking protein 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECE1 endothelin converting enzyme 1
EFNA3 ephrin-A3
EPHX2 epoxide hydrolase 2, cytoplasmic
F2R coagulation factor II (thrombin) receptor
FAM214B family with sequence similarity 214, member B
FH fumarate hydratase
GDAP1 ganglioside induced differentiation associated protein 1
GLP1R glucagon-like peptide 1 receptor
GREB1L growth regulation by estrogen in breast cancer-like
GSAP gamma-secretase activating protein
HIST1H4D histone cluster 1, H4d
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNMT histamine N-methyltransferase
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HPS1 Hermansky-Pudlak syndrome 1
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
IFT122 intraflagellar transport 122
ING1 inhibitor of growth family, member 1
IRS2 insulin receptor substrate 2
KHSRP KH-type splicing regulatory protein
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
KLF6 Kruppel-like factor 6
KLHL22 kelch-like family member 22
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LOC157562 uncharacterized LOC157562
LOC644450 uncharacterized LOC644450
LOXL3 lysyl oxidase-like 3
MAG myelin associated glycoprotein
MAN1A1 mannosidase, alpha, class 1A, member 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MITF microphthalmia-associated transcription factor
MMP10 matrix metallopeptidase 10
MMP13 matrix metallopeptidase 13
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCOA2 nuclear receptor coactivator 2
NCOR2 nuclear receptor corepressor 2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NNAT neuronatin
NPR1 natriuretic peptide receptor 1
OASL 2'-5'-oligoadenylate synthetase-like
PCM1 pericentriolar material 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDIA2 protein disulfide isomerase family A, member 2
PDLIM5 PDZ and LIM domain 5
PHF20 PHD finger protein 20
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK4 polo-like kinase 4
PMM1 phosphomannomutase 1
PRRX1 paired related homeobox 1
RAB3B RAB3B, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RPL7 ribosomal protein L7
SDC3 syndecan 3
SERHL2 serine hydrolase-like 2
SH2D1A SH2 domain containing 1A
SLC12A8 solute carrier family 12, member 8
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCG synuclein, gamma (breast cancer-specific protein 1)
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYBU syntabulin (syntaxin-interacting)
TACR1 tachykinin receptor 1
TBX6 T-box 6
THBS1 thrombospondin 1
TK2 thymidine kinase 2, mitochondrial
TOP3B topoisomerase (DNA) III beta
VAMP5 vesicle-associated membrane protein 5
VPS9D1 VPS9 domain containing 1
WNT10B wingless-type MMTV integration site family, member 10B
ZNF136 zinc finger protein 136
ZNF324 zinc finger protein 324
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATAD5 ATPase family, AAA domain containing 5
ATG7 autophagy related 7
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC85C coiled-coil domain containing 85C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP97 centrosomal protein 97kDa
CFAP69 cilia and flagella associated protein 69
CHMP6 charged multivesicular body protein 6
CLSPN claspin
CLSTN2 calsyntenin 2
CNN2 calponin 2
CTNNBIP1 catenin, beta interacting protein 1
DCAF10 DDB1 and CUL4 associated factor 10
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBRS fibrosin
FBXO31 F-box protein 31
FCHSD2 FCH and double SH3 domains 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BO histone cluster 1, H2bo
HOXC10 homeobox C10
IFT140 intraflagellar transport 140
IL4R interleukin 4 receptor
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2 interferon regulatory factor 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LHX6 LIM homeobox 6
LNPEP leucyl/cystinyl aminopeptidase
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC20 leucine rich repeat containing 20
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MFSD12 major facilitator superfamily domain containing 12
MUC3A mucin 3A, cell surface associated
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SCHIP1 schwannomin interacting protein 1
SIPA1 signal-induced proliferation-associated 1
SIRT6 sirtuin 6
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SSFA2 sperm specific antigen 2
STARD3 StAR-related lipid transfer (START) domain containing 3
STX5 syntaxin 5
TEAD3 TEA domain family member 3
TMEM104 transmembrane protein 104
TOM1 target of myb1 (chicken)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZC3H12A zinc finger CCCH-type containing 12A
ZNF205 zinc finger protein 205
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675