barrett's esophagus Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description Metaplasia of the lower esophagus that is characterized by replacement of squamous epithelium with columnar epithelium, occurs especially as a result of chronic gastroesophageal reflux, and is associated with an increased risk for esophageal carcinoma. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003427)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:9206
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Genes

17 genes associated with the disease barrett's esophagus in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
CRTC1 CREB regulated transcription coactivator 1 1.53704
BARX1 BARX homeobox 1 1.50906
PTPDC1 protein tyrosine phosphatase domain containing 1 1.34001
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.25477
GRID1 glutamate receptor, ionotropic, delta 1 1.02476
AGBL1 ATP/GTP binding protein-like 1 1.02476
FRMD3 FERM domain containing 3 0.95603
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.789217
LECT1 leukocyte cell derived chemotaxin 1 0.721812
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 0.704784
EPHB1 EPH receptor B1 0.637975
OSBPL10 oxysterol binding protein-like 10 0.616096
OTX2-AS1 OTX2 antisense RNA 1 (head to head) 0.601298
DSG3 desmoglein 3 0.59596
CAMTA1 calmodulin binding transcription activator 1 0.5757
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.563041
MIR99AHG mir-99a-let-7c cluster host gene 0.497756