barrier Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

464 genes co-occuring with the biological term barrier in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABHD5 abhydrolase domain containing 5
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTN1 actinin, alpha 1
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADCY6 adenylate cyclase 6
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADM2 adrenomedullin 2
ADORA2A adenosine A2a receptor
AFM afamin
AGER advanced glycosylation end product-specific receptor
AGRN agrin
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
ALPI alkaline phosphatase, intestinal
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANK1 ankyrin 1, erythrocytic
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
AQP4 aquaporin 4
AQP5 aquaporin 5
AQP8 aquaporin 8
ARHGAP29 Rho GTPase activating protein 29
ARHGAP35 Rho GTPase activating protein 35
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL13B ADP-ribosylation factor-like 13B
BAX BCL2-associated X protein
BMP2 bone morphogenetic protein 2
BPI bactericidal/permeability-increasing protein
CALML5 calmodulin-like 5
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMP cathelicidin antimicrobial peptide
CAPN2 calpain 2, (m/II) large subunit
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCM2 cerebral cavernous malformation 2
CCNA2 cyclin A2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD163 CD163 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDSN corneodesmosin
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CERS3 ceramide synthase 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHRM1 cholinergic receptor, muscarinic 1
CLDN1 claudin 1
CLDN11 claudin 11
CLDN2 claudin 2
CLDN3 claudin 3
CLDN4 claudin 4
CLDN5 claudin 5
CLDN7 claudin 7
CLDN8 claudin 8
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CRYGD crystallin, gamma D
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CTCF CCCTC-binding factor (zinc finger protein)
CTF1 cardiotrophin 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTRL chymotrypsin-like
CTSH cathepsin H
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DMBT1 deleted in malignant brain tumors 1
DMD dystrophin
DNM2 dynamin 2
DSG1 desmoglein 1
DSG2 desmoglein 2
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EDNRB endothelin receptor type B
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELK1 ELK1, member of ETS oncogene family
EMD emerin
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EVL Enah/Vasp-like
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EZR ezrin
F10 coagulation factor X
F11R F11 receptor
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FA2H fatty acid 2-hydroxylase
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FERMT3 fermitin family member 3
FGF2 fibroblast growth factor 2 (basic)
FGG fibrinogen gamma chain
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLG filaggrin
FLG2 filaggrin family member 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FXYD3 FXYD domain containing ion transport regulator 3
FYN FYN proto-oncogene, Src family tyrosine kinase
GBA glucosidase, beta, acid
GBP1 guanylate binding protein 1, interferon-inducible
GCG glucagon
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GKN1 gastrokine 1
GLRX glutaredoxin (thioltransferase)
GMCL1 germ cell-less, spermatogenesis associated 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPR39 G protein-coupled receptor 39
GRK1 G protein-coupled receptor kinase 1
GSN gelsolin
GUCY2C guanylate cyclase 2C
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2BK histone cluster 1, H2bk
HMGB1 high mobility group box 1
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HRNR hornerin
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL22 interleukin 22
IL27 interleukin 27
IL36B interleukin 36, beta
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITGB6 integrin, beta 6
JAK3 Janus kinase 3
JUND jun D proto-oncogene
KDR kinase insert domain receptor
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF2 Kruppel-like factor 2
KLK7 kallikrein-related peptidase 7
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
KRT1 keratin 1, type II
KRT16 keratin 16, type I
KRT20 keratin 20, type I
KRT8 keratin 8, type II
LAYN layilin
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LOR loricrin
LRP1 low density lipoprotein receptor-related protein 1
LRRK2 leucine-rich repeat kinase 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MARVELD2 MARVEL domain containing 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIR155 microRNA 155
MIR204 microRNA 204
MIR211 microRNA 211
MIR320A microRNA 320a
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MS4A8 membrane-spanning 4-domains, subfamily A, member 8
MSN moesin
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC17 mucin 17, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MYADM myeloid-associated differentiation marker
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MYLK myosin light chain kinase
MYO6 myosin VI
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NBN nibrin
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL4 NIPA-like domain containing 4
NLRX1 NLR family member X1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NONO non-POU domain containing, octamer-binding
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPSR1 neuropeptide S receptor 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRG1 neuregulin 1
NRP1 neuropilin 1
NUAK2 NUAK family, SNF1-like kinase, 2
NUP153 nucleoporin 153kDa
NUP62 nucleoporin 62kDa
NUP98 nucleoporin 98kDa
OCLN occludin
OIT3 oncoprotein induced transcript 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORM1 orosomucoid 1
PADI2 peptidyl arginine deiminase, type II
PAH phenylalanine hydroxylase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD10 programmed cell death 10
PDCD6IP programmed cell death 6 interacting protein
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2F phospholipase A2, group IIF
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G5 phospholipase A2, group V
PLAT plasminogen activator, tissue
PLCG1 phospholipase C, gamma 1
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLG plasminogen
PLTP phospholipid transfer protein
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PON1 paraoxonase 1
PPARD peroxisome proliferator-activated receptor delta
PPHLN1 periphilin 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD3 protein kinase D3
PRL prolactin
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PRSS8 protease, serine, 8
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD50 RAD50 homolog (S. cerevisiae)
RALBP1 ralA binding protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASIP1 Ras interacting protein 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RHOA ras homolog family member A
RHOD ras homolog family member D
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRAS related RAS viral (r-ras) oncogene homolog
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
S100A7 S100 calcium binding protein A7
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
S1PR5 sphingosine-1-phosphate receptor 5
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC1 syndecan 1
SELPLG selectin P ligand
SEPT2 septin 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD1A SET domain containing 1A
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GL2 SH3-domain GRB2-like 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC38A2 solute carrier family 38, member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOD1 superoxide dismutase 1, soluble
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SSRP1 structure specific recognition protein 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK25 serine/threonine kinase 25
STK39 serine threonine kinase 39
STOM stomatin
STS steroid sulfatase (microsomal), isozyme S
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYN1 synapsin I
TACSTD2 tumor-associated calcium signal transducer 2
TARDBP TAR DNA binding protein
TEK TEK tyrosine kinase, endothelial
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TF transferrin
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGM1 transglutaminase 1
TGM3 transglutaminase 3
THBS1 thrombospondin 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TMEM231 transmembrane protein 231
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM5 tripartite motif containing 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTR transthyretin
TYRO3 TYRO3 protein tyrosine kinase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UMOD uromodulin
UTRN utrophin
VASP vasodilator-stimulated phosphoprotein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
WTIP Wilms tumor 1 interacting protein
XPO1 exportin 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta