basal cell carcinoma Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471). (Experimental Factor Ontology, EFO_0004193)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa05217.html
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Genes

55 proteins participating in the basal cell carcinoma pathway from the KEGG Pathways dataset.

Symbol Name
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
AXIN1 axin 1
AXIN2 axin 2
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
FZD1 frizzled class receptor 1
FZD10 frizzled class receptor 10
FZD2 frizzled class receptor 2
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
FZD8 frizzled class receptor 8
FZD9 frizzled class receptor 9
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GSK3B glycogen synthase kinase 3 beta
HHIP hedgehog interacting protein
LEF1 lymphoid enhancer-binding factor 1
PTCH1 patched 1
PTCH2 patched 2
SHH sonic hedgehog
SMO smoothened, frizzled class receptor
STK36 serine/threonine kinase 36
SUFU suppressor of fused homolog (Drosophila)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TP53 tumor protein p53
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
WNT8A wingless-type MMTV integration site family, member 8A
WNT8B wingless-type MMTV integration site family, member 8B
WNT9A wingless-type MMTV integration site family, member 9A
WNT9B wingless-type MMTV integration site family, member 9B