bche Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description butyrylcholinesterase|Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 590)
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Genes

10 genes co-occuring with the biological term bche in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
APOE apolipoprotein E
BCHE butyrylcholinesterase
CHAT choline O-acetyltransferase
EPHB4 EPH receptor B4
IAPP islet amyloid polypeptide
MME membrane metallo-endopeptidase
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta