bcl-2 family protein complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed. (Gene Ontology, GO_0097136)
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4 proteins localized to the bcl-2 family protein complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MCL1 myeloid cell leukemia 1 0.663342
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.663342
BCL2L1 BCL2-like 1 0.663342
BAX BCL2-associated X protein 0.663342