bcl11b Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description B-cell CLL/lymphoma 11B (zinc finger protein)|This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 64919)
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Genes

11 genes co-occuring with the biological term bcl11b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L1 BCL2-like 1
CREBBP CREB binding protein
FLT3 fms-related tyrosine kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NKX2-5 NK2 homeobox 5
NOTCH1 notch 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TP53 tumor protein p53