bcl3 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description B-cell CLL/lymphoma 3|This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 602)
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Genes

28 genes co-occuring with the biological term bcl3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
CCND1 cyclin D1
CRTC3 CREB regulated transcription coactivator 3
CTBP1 C-terminal binding protein 1
CYLD cylindromatosis (turban tumor syndrome)
ESR1 estrogen receptor 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
HDAC1 histone deacetylase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL6 interleukin 6
IRS3P insulin receptor substrate 3, pseudogene
JUN jun proto-oncogene
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHBDD1 rhomboid domain containing 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TP53 tumor protein p53
UBE2L3 ubiquitin-conjugating enzyme E2L 3