beclometasone-4403 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the beclometasone-4403 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
AFF3 AF4/FMR2 family, member 3
ALDOB aldolase B, fructose-bisphosphate
APOH apolipoprotein H (beta-2-glycoprotein I)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPH aspartate beta-hydroxylase
ATG10 autophagy related 10
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BDKRB2 bradykinin receptor B2
C1QB complement component 1, q subcomponent, B chain
C21ORF2 chromosome 21 open reading frame 2
CADM4 cell adhesion molecule 4
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CCDC81 coiled-coil domain containing 81
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEL carboxyl ester lipase
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLCN1 chloride channel, voltage-sensitive 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAO D-amino-acid oxidase
DGCR8 DGCR8 microprocessor complex subunit
DYM dymeclin
EDN2 endothelin 2
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
EXOSC2 exosome component 2
FABP3 fatty acid binding protein 3, muscle and heart
FABP6 fatty acid binding protein 6, ileal
FAM105A family with sequence similarity 105, member A
FGF4 fibroblast growth factor 4
FSCN3 fascin actin-bundling protein 3, testicular
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GK glycerol kinase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR162 G protein-coupled receptor 162
GUCA1A guanylate cyclase activator 1A (retina)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIPK2 homeodomain interacting protein kinase 2
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
INHBE inhibin, beta E
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
JAM3 junctional adhesion molecule 3
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIFC3 kinesin family member C3
KLF13 Kruppel-like factor 13
KLF9 Kruppel-like factor 9
LAMC2 laminin, gamma 2
LAPTM5 lysosomal protein transmembrane 5
LGALS9 lectin, galactoside-binding, soluble, 9
LIMK1 LIM domain kinase 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MBD2 methyl-CpG binding domain protein 2
NCOR2 nuclear receptor corepressor 2
NDRG2 NDRG family member 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP188 nucleoporin 188kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OGDHL oxoglutarate dehydrogenase-like
ONECUT1 one cut homeobox 1
OSBPL7 oxysterol binding protein-like 7
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLCH1 phospholipase C, eta 1
PML promyelocytic leukemia
POU5F1B POU class 5 homeobox 1B
PRB4 proline-rich protein BstNI subfamily 4
PRTN3 proteinase 3
PSCA prostate stem cell antigen
RAB6A RAB6A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPL7 ribosomal protein L7
RUNX3 runt-related transcription factor 3
SCLY selenocysteine lyase
SECTM1 secreted and transmembrane 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOAT2 sterol O-acyltransferase 2
SPAG8 sperm associated antigen 8
SPEG SPEG complex locus
SPN sialophorin
SPRR1B small proline-rich protein 1B
STAB2 stabilin 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM38 tripartite motif containing 38
TTC39A tetratricopeptide repeat domain 39A
TUBA3C tubulin, alpha 3c
VWA5A von Willebrand factor A domain containing 5A
XAF1 XIAP associated factor 1
ZNF358 zinc finger protein 358
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AKAP12 A kinase (PRKA) anchor protein 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGAP10 Rho GTPase activating protein 10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSB arylsulfatase B
ATF7IP2 activating transcription factor 7 interacting protein 2
BAX BCL2-associated X protein
BFSP1 beaded filament structural protein 1, filensin
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CCP110 centriolar coiled coil protein 110kDa
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYGC crystallin, gamma C
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAF1 DEAF1 transcription factor
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EMID1 EMI domain containing 1
ERCC2 excision repair cross-complementation group 2
F2R coagulation factor II (thrombin) receptor
FBXO2 F-box protein 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FLT4 fms-related tyrosine kinase 4
FOXI1 forkhead box I1
GADD45G growth arrest and DNA-damage-inducible, gamma
GBAS glioblastoma amplified sequence
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD1C GRAM domain containing 1C
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BM histone cluster 1, H2bm
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IRF9 interferon regulatory factor 9
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LMNB1 lamin B1
MDM4 MDM4, p53 regulator
MEGF6 multiple EGF-like-domains 6
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MX2 MX dynamin-like GTPase 2
NEUROD1 neuronal differentiation 1
NFE2L3 nuclear factor, erythroid 2-like 3
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
NPY4R neuropeptide Y receptor Y4
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PNPLA6 patatin-like phospholipase domain containing 6
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCE protein kinase C, epsilon
PTDSS2 phosphatidylserine synthase 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC22A14 solute carrier family 22, member 14
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SPRR2B small proline-rich protein 2B
THRAP3 thyroid hormone receptor associated protein 3
TLN1 talin 1
TMEM209 transmembrane protein 209
TPSG1 tryptase gamma 1
TRIM21 tripartite motif containing 21
TSC22D4 TSC22 domain family, member 4
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF552 zinc finger protein 552