beclometasone-4580 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the beclometasone-4580 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTG2 actin, gamma 2, smooth muscle, enteric
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPTL4 angiopoietin-like 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARTN artemin
BTG2 BTG family, member 2
C10ORF12 chromosome 10 open reading frame 12
C1ORF116 chromosome 1 open reading frame 116
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CIDEC cell death-inducing DFFA-like effector c
CLDN1 claudin 1
CLTCL1 clathrin, heavy chain-like 1
COL3A1 collagen, type III, alpha 1
CREM cAMP responsive element modulator
CTNND2 catenin (cadherin-associated protein), delta 2
CXCR3 chemokine (C-X-C motif) receptor 3
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
EFNB2 ephrin-B2
FASLG Fas ligand (TNF superfamily, member 6)
FDX1 ferredoxin 1
FLT1 fms-related tyrosine kinase 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GK2 glycerol kinase 2
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GPR137 G protein-coupled receptor 137
GRM7 glutamate receptor, metabotropic 7
HIST1H2AB histone cluster 1, H2ab
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXD9 homeobox D9
HPS1 Hermansky-Pudlak syndrome 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL6R interleukin 6 receptor
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM6B lysine (K)-specific demethylase 6B
KLHL28 kelch-like family member 28
LAT2 linker for activation of T cells family, member 2
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMAN1 lectin, mannose-binding, 1
LRRC23 leucine rich repeat containing 23
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MCL1 myeloid cell leukemia 1
MCOLN3 mucolipin 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAV2 neuron navigator 2
NCLN nicalin
NNMT nicotinamide N-methyltransferase
NR4A1 nuclear receptor subfamily 4, group A, member 1
PALM paralemmin
PER1 period circadian clock 1
PLAT plasminogen activator, tissue
POFUT1 protein O-fucosyltransferase 1
PRTN3 proteinase 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PYY peptide YY
RAD23B RAD23 homolog B (S. cerevisiae)
RAP1GAP2 RAP1 GTPase activating protein 2
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REEP1 receptor accessory protein 1
RNASE4 ribonuclease, RNase A family, 4
RYR2 ryanodine receptor 2 (cardiac)
SC5D sterol-C5-desaturase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SNAI2 snail family zinc finger 2
SOX15 SRY (sex determining region Y)-box 15
SPRED2 sprouty-related, EVH1 domain containing 2
SPTBN1 spectrin, beta, non-erythrocytic 1
STS steroid sulfatase (microsomal), isozyme S
SUSD5 sushi domain containing 5
TG thyroglobulin
TGS1 trimethylguanosine synthase 1
THBS1 thrombospondin 1
TLR2 toll-like receptor 2
TM4SF4 transmembrane 4 L six family member 4
TNIK TRAF2 and NCK interacting kinase
TSC22D3 TSC22 domain family, member 3
TTLL1 tubulin tyrosine ligase-like family member 1
UBE3A ubiquitin protein ligase E3A
WSB1 WD repeat and SOCS box containing 1
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP2 ZFP2 zinc finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AEN apoptosis enhancing nuclease
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOLD1 apolipoprotein L domain containing 1
ARL14 ADP-ribosylation factor-like 14
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BEND5 BEN domain containing 5
BICC1 BicC family RNA binding protein 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF79 chromosome 14 open reading frame 79
C19ORF40 chromosome 19 open reading frame 40
C1ORF105 chromosome 1 open reading frame 105
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CARD8 caspase recruitment domain family, member 8
CCP110 centriolar coiled coil protein 110kDa
CES3 carboxylesterase 3
CHST10 carbohydrate sulfotransferase 10
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEB cell death-inducing DFFA-like effector b
CLDN11 claudin 11
CLSTN3 calsyntenin 3
CNTNAP3B contactin associated protein-like 3B
COL9A3 collagen, type IX, alpha 3
CPA4 carboxypeptidase A4
CPNE7 copine VII
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELMO3 engulfment and cell motility 3
EN2 engrailed homeobox 2
FA2H fatty acid 2-hydroxylase
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GAS2 growth arrest-specific 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPR guanosine monophosphate reductase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRAMD1C GRAM domain containing 1C
HDAC11 histone deacetylase 11
HOXA4 homeobox A4
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT54 intraflagellar transport 54
IL11RA interleukin 11 receptor, alpha
IL17RB interleukin 17 receptor B
IL1B interleukin 1, beta
IL7 interleukin 7
KCTD17 potassium channel tetramerization domain containing 17
KRT86 keratin 86, type II
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LYPD1 LY6/PLAUR domain containing 1
MLYCD malonyl-CoA decarboxylase
MNMIP1 manchette microtubule inner protein 1
MXD3 MAX dimerization protein 3
MXRA8 matrix-remodelling associated 8
NT5M 5',3'-nucleotidase, mitochondrial
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM2 PDZ and LIM domain 2 (mystique)
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD2 phospholipase D2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SAA4 serum amyloid A4, constitutive
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SIRAL2 SIR2 antiphage like 2
SLC22A18 solute carrier family 22, member 18
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOBP sine oculis binding protein homolog (Drosophila)
STAC SH3 and cysteine rich domain
TBKBP1 TBK1 binding protein 1
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TONSL tonsoku-like, DNA repair protein
TSC22D4 TSC22 domain family, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VN1R1 vomeronasal 1 receptor 1
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB22 zinc finger and BTB domain containing 22
ZFHX2 zinc finger homeobox 2
ZFHX3 zinc finger homeobox 3
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76