bemegride-3051 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bemegride-3051 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADAM12 ADAM metallopeptidase domain 12
ADCY1 adenylate cyclase 1 (brain)
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALD1 caldesmon 1
CCDC9 coiled-coil domain containing 9
CDC25C cell division cycle 25C
CDH10 cadherin 10, type 2 (T2-cadherin)
CHD5 chromodomain helicase DNA binding protein 5
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLUL1 clusterin-like 1 (retinal)
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CSPG4 chondroitin sulfate proteoglycan 4
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DAAM2 dishevelled associated activator of morphogenesis 2
DCHS2 dachsous cadherin-related 2
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOK5 docking protein 5
EDA ectodysplasin A
EGLN3 egl-9 family hypoxia-inducible factor 3
ELF5 E74-like factor 5 (ets domain transcription factor)
EMC3 ER membrane protein complex subunit 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA4 EPH receptor A4
EPHB3 EPH receptor B3
ESR1 estrogen receptor 1
EXPH5 exophilin 5
FHL1 four and a half LIM domains 1
FOXJ1 forkhead box J1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAL3ST4 galactose-3-O-sulfotransferase 4
GJA4 gap junction protein, alpha 4, 37kDa
GJA8 gap junction protein, alpha 8, 50kDa
GPATCH4 G patch domain containing 4
GPC1 glypican 1
GPR157 G protein-coupled receptor 157
GPR20 G protein-coupled receptor 20
GPR6 G protein-coupled receptor 6
GSTTP1 glutathione S-transferase theta pseudogene 1
GTPBP1 GTP binding protein 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H1T histone cluster 1, H1t
IL6ST interleukin 6 signal transducer
IMPG2 interphotoreceptor matrix proteoglycan 2
KCTD17 potassium channel tetramerization domain containing 17
KIFC3 kinesin family member C3
KLF5 Kruppel-like factor 5 (intestinal)
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
KRT14 keratin 14, type I
LHX2 LIM homeobox 2
LRRC17 leucine rich repeat containing 17
LTBP3 latent transforming growth factor beta binding protein 3
MEG3 maternally expressed 3 (non-protein coding)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYH11 myosin, heavy chain 11, smooth muscle
NID1 nidogen 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
OVOL2 ovo-like zinc finger 2
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEG10 paternally expressed 10
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLN phospholamban
PTCRA pre T-cell antigen receptor alpha
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTRF polymerase I and transcript release factor
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB26 RAB26, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RTEL1 regulator of telomere elongation helicase 1
SCAND2P SCAN domain containing 2 pseudogene
SCNN1D sodium channel, non voltage gated 1 delta subunit
SERHL2 serine hydrolase-like 2
SH3BP1 SH3-domain binding protein 1
SI sucrase-isomaltase (alpha-glucosidase)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPEF1 sperm flagellar 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TBC1D2 TBC1 domain family, member 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRAPPC9 trafficking protein particle complex 9
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TYMP thymidine phosphorylase
ZNF276 zinc finger protein 276
ZNF446 zinc finger protein 446
ZNF507 zinc finger protein 507
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACOX2 acyl-CoA oxidase 2, branched chain
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC4 apolipoprotein C-IV
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARMCX4 armadillo repeat containing, X-linked 4
BCAR3 breast cancer anti-estrogen resistance 3
C8A complement component 8, alpha polypeptide
CCL20 chemokine (C-C motif) ligand 20
CD70 CD70 molecule
CELP carboxyl ester lipase pseudogene
CFAP69 cilia and flagella associated protein 69
CFP complement factor properdin
CLCF1 cardiotrophin-like cytokine factor 1
CROT carnitine O-octanoyltransferase
CRY1 cryptochrome circadian clock 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EXO5 exonuclease 5
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
FMOD fibromodulin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1B histone cluster 1, H1b
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB9 homeobox B9
HOXC8 homeobox C8
IBSP integrin-binding sialoprotein
IFT140 intraflagellar transport 140
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INHBA inhibin, beta A
KCNK5 potassium channel, two pore domain subfamily K, member 5
KRT31 keratin 31, type I
LIME1 Lck interacting transmembrane adaptor 1
LRRK1 leucine-rich repeat kinase 1
LTBP2 latent transforming growth factor beta binding protein 2
MANSC1 MANSC domain containing 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MICA MHC class I polypeptide-related sequence A
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
MRPL44 mitochondrial ribosomal protein L44
NCS1 neuronal calcium sensor 1
NINJ2 ninjurin 2
NPFFR1 neuropeptide FF receptor 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PBOV1 prostate and breast cancer overexpressed 1
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIR pirin (iron-binding nuclear protein)
PROCR protein C receptor, endothelial
RAB17 RAB17, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RECQL4 RecQ protein-like 4
SALL2 spalt-like transcription factor 2
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC16A6 solute carrier family 16, member 6
SLC17A2 solute carrier family 17, member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP1 Sp1 transcription factor
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TASP1 taspase, threonine aspartase, 1
TBXAS1 thromboxane A synthase 1 (platelet)
TDRD3 tudor domain containing 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM19 transmembrane protein 19
TMEM242 transmembrane protein 242
TRPS1 trichorhinophalangeal syndrome I
TSC22D4 TSC22 domain family, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XYLT2 xylosyltransferase II
ZBTB38 zinc finger and BTB domain containing 38
ZDHHC14 zinc finger, DHHC-type containing 14
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF215 zinc finger protein 215
ZNF286A zinc finger protein 286A
ZNF428 zinc finger protein 428
ZNF668 zinc finger protein 668
ZNF768 zinc finger protein 768