bemegride-3389 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bemegride-3389 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADGRA2 adhesion G protein-coupled receptor A2
AGMAT agmatine ureohydrolase (agmatinase)
AKAP8L A kinase (PRKA) anchor protein 8-like
ALCAM activated leukocyte cell adhesion molecule
ANGPTL2 angiopoietin-like 2
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CA9 carbonic anhydrase IX
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD300C CD300c molecule
CD47 CD47 molecule
CDH8 cadherin 8, type 2
CLIC2 chloride intracellular channel 2
CNN1 calponin 1, basic, smooth muscle
COL14A1 collagen, type XIV, alpha 1
COL16A1 collagen, type XVI, alpha 1
CPNE7 copine VII
CREBBP CREB binding protein
CRTC1 CREB regulated transcription coactivator 1
CXXC4 CXXC finger protein 4
CYLD cylindromatosis (turban tumor syndrome)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DHRS7 dehydrogenase/reductase (SDR family) member 7
DIO2 deiodinase, iodothyronine, type II
DKFZP434C153 DKFZP434C153 protein
DSC1 desmocollin 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM46C family with sequence similarity 46, member C
FLJ11292
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GP6 glycoprotein VI (platelet)
GPR75 G protein-coupled receptor 75
HCFC1 host cell factor C1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIPK2 homeodomain interacting protein kinase 2
HOXA9 homeobox A9
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IL5RA interleukin 5 receptor, alpha
IQCC IQ motif containing C
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1462 KIAA1462
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LMTK1 lemur tail kinase 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LTB4R leukotriene B4 receptor
MALL mal, T-cell differentiation protein-like
MRPL41 mitochondrial ribosomal protein L41
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
NME5 NME/NM23 family member 5
NOX1 NADPH oxidase 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRTN neurturin
PCDHB11 protocadherin beta 11
PCNXL2 pecanex-like 2 (Drosophila)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PML promyelocytic leukemia
PPP5C protein phosphatase 5, catalytic subunit
PTPRH protein tyrosine phosphatase, receptor type, H
RAB6B RAB6B, member RAS oncogene family
REC8 REC8 meiotic recombination protein
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SH3GL3 SH3-domain GRB2-like 3
SIM2 single-minded family bHLH transcription factor 2
SIPA1 signal-induced proliferation-associated 1
SLC39A9 solute carrier family 39, member 9
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNW1 SNW domain containing 1
SORBS1 sorbin and SH3 domain containing 1
SRRT serrate, RNA effector molecule
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TBXA2R thromboxane A2 receptor
TERT telomerase reverse transcriptase
TMCC2 transmembrane and coiled-coil domain family 2
TPSG1 tryptase gamma 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WLS wntless Wnt ligand secretion mediator
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADTRP androgen-dependent TFPI-regulating protein
ATAT1 alpha tubulin acetyltransferase 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
B9D2 B9 protein domain 2
C14ORF79 chromosome 14 open reading frame 79
C1QB complement component 1, q subcomponent, B chain
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3 complement component 3
C5AR2 complement component 5a receptor 2
C8ORF44 chromosome 8 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNK cyclin K
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
DBF4B DBF4 zinc finger B
DOK5 docking protein 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDAR ectodysplasin A receptor
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FICD FIC domain containing
FSCN3 fascin actin-bundling protein 3, testicular
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GPR27 G protein-coupled receptor 27
GPR85 G protein-coupled receptor 85
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H2BO histone cluster 1, H2bo
HIST1H4A histone cluster 1, H4a
HIST1H4D histone cluster 1, H4d
HOXA4 homeobox A4
HP1BP3 heterochromatin protein 1, binding protein 3
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INHA inhibin, alpha
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KRT24 keratin 24, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LINC00341 long intergenic non-protein coding RNA 341
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEA3 melanoma antigen family A3
MAPK10 mitogen-activated protein kinase 10
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MDM4 MDM4, p53 regulator
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MYO1F myosin IF
NCALD neurocalcin delta
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
OLFML2A olfactomedin-like 2A
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVOL1 ovo-like zinc finger 1
PDE8B phosphodiesterase 8B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMEL premelanosome protein
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RAB3A RAB3A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCAN3 RCAN family member 3
RNF126P1 ring finger protein 126 pseudogene 1
RPAP2 RNA polymerase II associated protein 2
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNTA1 syntrophin, alpha 1
SP1 Sp1 transcription factor
SPON2 spondin 2, extracellular matrix protein
STMN3 stathmin-like 3
TBL1Y transducin (beta)-like 1, Y-linked
TCTN2 tectonic family member 2
TICAM1 toll-like receptor adaptor molecule 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM45A transmembrane protein 45A
TRAIP TRAF interacting protein
TUBBP5 tubulin, beta pseudogene 5
WDR78 WD repeat domain 78
WFDC2 WAP four-disulfide core domain 2
XYLT1 xylosyltransferase I
ZNF230 zinc finger protein 230
ZNF41 zinc finger protein 41