bemegride-5014 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bemegride-5014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
AOC2 amine oxidase, copper containing 2 (retina-specific)
AOC3 amine oxidase, copper containing 3
APOM apolipoprotein M
BMP4 bone morphogenetic protein 4
BST2 bone marrow stromal cell antigen 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP135 centrosomal protein 135kDa
CEP164 centrosomal protein 164kDa
COMT catechol-O-methyltransferase
CUL7 cullin 7
CXORF21 chromosome X open reading frame 21
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DGAT1 diacylglycerol O-acyltransferase 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
E2F5 E2F transcription factor 5, p130-binding
EHD2 EH-domain containing 2
ELP6 elongator acetyltransferase complex subunit 6
EMC3 ER membrane protein complex subunit 3
FAM46C family with sequence similarity 46, member C
FBXO41 F-box protein 41
FKBP8 FK506 binding protein 8, 38kDa
FLJ42627 uncharacterized LOC645644
GJB3 gap junction protein, beta 3, 31kDa
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR22 G protein-coupled receptor 22
GSN gelsolin
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HCRP1 hepatocellular carcinoma-related HCRP1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1B interleukin 1, beta
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK13 mitogen-activated protein kinase 13
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST3 microtubule associated serine/threonine kinase 3
MTM1 myotubularin 1
MX1 MX dynamin-like GTPase 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEB nebulin
NR1H4 nuclear receptor subfamily 1, group H, member 4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PAX5 paired box 5
PCGF2 polycomb group ring finger 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PYY peptide YY
RAD23B RAD23 homolog B (S. cerevisiae)
RGS20 regulator of G-protein signaling 20
RGS3 regulator of G-protein signaling 3
RPL35A ribosomal protein L35a
SAMD4A sterile alpha motif domain containing 4A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIRT5 sirtuin 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SP110 SP110 nuclear body protein
SPINK4 serine peptidase inhibitor, Kazal type 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STC1 stanniocalcin 1
TAOK2 TAO kinase 2
TLR2 toll-like receptor 2
TRIM29 tripartite motif containing 29
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF407 zinc finger protein 407
ZNF428 zinc finger protein 428
ZNF609 zinc finger protein 609
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
ANP32A-IT1 ANP32A intronic transcript 1
BAGE B melanoma antigen
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CD83 CD83 molecule
CFD complement factor D (adipsin)
CLGN calmegin
COPS7B COP9 signalosome subunit 7B
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
EFNA3 ephrin-A3
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM53B family with sequence similarity 53, member B
FER fer (fps/fes related) tyrosine kinase
FGL1 fibrinogen-like 1
FLCN folliculin
FLJ11710 uncharacterized protein FLJ11710
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRB7 growth factor receptor-bound protein 7
HSPA1L heat shock 70kDa protein 1-like
IFT54 intraflagellar transport 54
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0355 KIAA0355
KLF2 Kruppel-like factor 2
LOC729164 hCG1732469
MALL mal, T-cell differentiation protein-like
MANBA mannosidase, beta A, lysosomal
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCC mutated in colorectal cancers
MFSD12 major facilitator superfamily domain containing 12
MSI1 musashi RNA-binding protein 1
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
OVGP1 oviductal glycoprotein 1, 120kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PGBD5 piggyBac transposable element derived 5
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCE protein kinase C, epsilon
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBM38 RNA binding motif protein 38
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RFTN1 raftlin, lipid raft linker 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIX1 SIX homeobox 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SNTA1 syntrophin, alpha 1
STAG3 stromal antigen 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCP10 t-complex 10
TCTN1 tectonic family member 1
THRAP3 thyroid hormone receptor associated protein 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSPAN1 tetraspanin 1
TSPYL2 TSPY-like 2
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZNRD1-AS1 ZNRD1 antisense RNA 1