| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the bendroflumethiazide-2555 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATP10A | ATPase, class V, type 10A |
| ATP10B | ATPase, class V, type 10B |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BMP8B | bone morphogenetic protein 8b |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC181 | coiled-coil domain containing 181 |
| CD52 | CD52 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CLCA1 | chloride channel accessory 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CUL4B | cullin 4B |
| CUX2 | cut-like homeobox 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ETV7 | ets variant 7 |
| EXPH5 | exophilin 5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FGF5 | fibroblast growth factor 5 |
| FRMD8 | FERM domain containing 8 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPR15 | G protein-coupled receptor 15 |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| HN1L | hematological and neurological expressed 1-like |
| HSF1 | heat shock transcription factor 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KEL | Kell blood group, metallo-endopeptidase |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KIF5C | kinesin family member 5C |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHL18 | kelch-like family member 18 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MECOM | MDS1 and EVI1 complex locus |
| MEFV | Mediterranean fever |
| MMP3 | matrix metallopeptidase 3 |
| MRC2 | mannose receptor, C type 2 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRCAM | neuronal cell adhesion molecule |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PKP4 | plakophilin 4 |
| PLIN2 | perilipin 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRLH | prolactin releasing hormone |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| REC8 | REC8 meiotic recombination protein |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SFTPB | surfactant protein B |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLAMF8 | SLAM family member 8 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SPTB | spectrin, beta, erythrocytic |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAB2 | stabilin 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBX6 | T-box 6 |
| TLN2 | talin 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF362 | zinc finger protein 362 |
| ZNF492 | zinc finger protein 492 |
| ZNF589 | zinc finger protein 589 |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| AIRE | autoimmune regulator |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA2P2 | annexin A2 pseudogene 2 |
| ARSB | arylsulfatase B |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG9A | autophagy related 9A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5 | complement component 5 |
| C5AR1 | complement component 5a receptor 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CD101 | CD101 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK20 | cyclin-dependent kinase 20 |
| CDON | cell adhesion associated, oncogene regulated |
| CFP | complement factor properdin |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CKB | creatine kinase, brain |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CTSO | cathepsin O |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DOK3 | docking protein 3 |
| DSE | dermatan sulfate epimerase |
| DSPP | dentin sialophosphoprotein |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ENO3 | enolase 3 (beta, muscle) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM63A | family with sequence similarity 63, member A |
| FBRS | fibrosin |
| FGF6 | fibroblast growth factor 6 |
| FILIP1L | filamin A interacting protein 1-like |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HSPA2 | heat shock 70kDa protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IRF7 | interferon regulatory factor 7 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL21 | kelch-like family member 21 |
| KLHL36 | kelch-like family member 36 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100287590 | uncharacterized LOC100287590 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MICA | MHC class I polypeptide-related sequence A |
| MRAS | muscle RAS oncogene homolog |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PCBP4 | poly(rC) binding protein 4 |
| PCDH12 | protocadherin 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| POM121 | POM121 transmembrane nucleoporin |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF25 | ring finger protein 25 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SERTAD3 | SERTA domain containing 3 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| STAT5A | signal transducer and activator of transcription 5A |
| STBD1 | starch binding domain 1 |
| STX11 | syntaxin 11 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIB2 | tribbles pseudokinase 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK3A | uroplakin 3A |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF506 | zinc finger protein 506 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
