| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the bendroflumethiazide-3415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AEN | apoptosis enhancing nuclease |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOM | apolipoprotein M |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARMC4 | armadillo repeat containing 4 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CD82 | CD82 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK13 | cyclin-dependent kinase 13 |
| COMT | catechol-O-methyltransferase |
| CTTN | cortactin |
| DOC2A | double C2-like domains, alpha |
| EGR3 | early growth response 3 |
| EXOC7 | exocyst complex component 7 |
| EXPH5 | exophilin 5 |
| FADS3 | fatty acid desaturase 3 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GPATCH4 | G patch domain containing 4 |
| GPR4 | G protein-coupled receptor 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H4D | histone cluster 1, H4d |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ICAM1 | intercellular adhesion molecule 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL1B | interleukin 1, beta |
| INCENP | inner centromere protein antigens 135/155kDa |
| INSR | insulin receptor |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMAN1 | lectin, mannose-binding, 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAP9 | microtubule-associated protein 9 |
| MCAM | melanoma cell adhesion molecule |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MIIP | migration and invasion inhibitory protein |
| MSMB | microseminoprotein, beta- |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3A | mucin 3A, cell surface associated |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFIB | nuclear factor I/B |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUP188 | nucleoporin 188kDa |
| OLFML2A | olfactomedin-like 2A |
| PARD6B | par-6 family cell polarity regulator beta |
| PCGF3 | polycomb group ring finger 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLAUR | plasminogen activator, urokinase receptor |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RARA | retinoic acid receptor, alpha |
| RASAL2 | RAS protein activator like 2 |
| RGS12 | regulator of G-protein signaling 12 |
| SAFB | scaffold attachment factor B |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMIM8 | small integral membrane protein 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| STEAP4 | STEAP family member 4 |
| STK4 | serine/threonine kinase 4 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TDRKH | tudor and KH domain containing |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGM2 | transglutaminase 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMCO6 | transmembrane and coiled-coil domains 6 |
| TMOD1 | tropomodulin 1 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TPP1 | tripeptidyl peptidase I |
| TSGA10 | testis specific, 10 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR55 | WD repeat domain 55 |
| WDR62 | WD repeat domain 62 |
| WSCD1 | WSC domain containing 1 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AGO1 | argonaute RISC catalytic component 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARMC7 | armadillo repeat containing 7 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CASD1 | CAS1 domain containing 1 |
| CBX7 | chromobox homolog 7 |
| CEP72 | centrosomal protein 72kDa |
| CEP97 | centrosomal protein 97kDa |
| CLMN | calmin (calponin-like, transmembrane) |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COL4A5 | collagen, type IV, alpha 5 |
| CXORF56 | chromosome X open reading frame 56 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| E2F1 | E2F transcription factor 1 |
| EFNA3 | ephrin-A3 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPHA4 | EPH receptor A4 |
| ERCC4 | excision repair cross-complementation group 4 |
| EVPL | envoplakin |
| FANCE | Fanconi anemia, complementation group E |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FOXK2 | forkhead box K2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUZ | fuzzy planar cell polarity protein |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRAMD4 | GRAM domain containing 4 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIRA | histone cell cycle regulator |
| HOXC13 | homeobox C13 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IREB2 | iron-responsive element binding protein 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MED15 | mediator complex subunit 15 |
| MID1IP1 | MID1 interacting protein 1 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NEO1 | neogenin 1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PANK4 | pantothenate kinase 4 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNF170 | ring finger protein 170 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCAP | SREBF chaperone |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SHARPIN | SHANK-associated RH domain interactor |
| SHPK | sedoheptulokinase |
| SIK1 | salt-inducible kinase 1 |
| SIRT2 | sirtuin 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SUSD6 | sushi domain containing 6 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TEAD3 | TEA domain family member 3 |
| TESK2 | testis-specific kinase 2 |
| THBS3 | thrombospondin 3 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM28 | tripartite motif containing 28 |
| TSPYL2 | TSPY-like 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBL4A | ubiquitin-like 4A |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF268 | zinc finger protein 268 |
| ZNF350 | zinc finger protein 350 |
| ZNF652 | zinc finger protein 652 |