bendroflumethiazide-3758 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bendroflumethiazide-3758 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM8 ADAM metallopeptidase domain 8
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALPK3 alpha-kinase 3
ARNT aryl hydrocarbon receptor nuclear translocator
ARSA arylsulfatase A
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BBC3 BCL2 binding component 3
BTNL3 butyrophilin-like 3
C3AR1 complement component 3a receptor 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CEND1 cell cycle exit and neuronal differentiation 1
CFAP70 cilia and flagella associated protein 70
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC4E C-type lectin domain family 4, member E
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
COL10A1 collagen, type X, alpha 1
CRAT carnitine O-acetyltransferase
CRYGC crystallin, gamma C
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DICER1 dicer 1, ribonuclease type III
DUSP1 dual specificity phosphatase 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERC2 ELKS/RAB6-interacting/CAST family member 2
ESR1 estrogen receptor 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FHL3 four and a half LIM domains 3
FNDC4 fibronectin type III domain containing 4
FOLR1 folate receptor 1 (adult)
FRMD4B FERM domain containing 4B
FRMPD1 FERM and PDZ domain containing 1
FZD1 frizzled class receptor 1
GBP2 guanylate binding protein 2, interferon-inducible
GFRA1 GDNF family receptor alpha 1
GGT1 gamma-glutamyltransferase 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GTPBP1 GTP binding protein 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HHLA1 HERV-H LTR-associating 1
HIST1H3A histone cluster 1, H3a
HNF4A hepatocyte nuclear factor 4, alpha
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFT38 intraflagellar transport 38
IL36G interleukin 36, gamma
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA8 integrin, alpha 8
KAT8 K(lysine) acetyltransferase 8
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KRT24 keratin 24, type I
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
MAPK8 mitogen-activated protein kinase 8
MEFV Mediterranean fever
NEK9 NIMA-related kinase 9
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTN1 netrin 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PCDHB3 protocadherin beta 3
PDGFB platelet-derived growth factor beta polypeptide
PER2 period circadian clock 2
PRDM1 PR domain containing 1, with ZNF domain
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYGO1 pygopus family PHD finger 1
RAB3D RAB3D, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF17 ring finger protein 17
RRH retinal pigment epithelium-derived rhodopsin homolog
RS1 retinoschisin 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERHL2 serine hydrolase-like 2
SKIL SKI-like proto-oncogene
SLA Src-like-adaptor
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPX spexin hormone
STARD8 StAR-related lipid transfer (START) domain containing 8
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
T T, brachyury homolog (mouse)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBCD tubulin folding cofactor D
TESC tescalcin
TLK1 tousled-like kinase 1
TPR translocated promoter region, nuclear basket protein
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPRBP Vpr (HIV-1) binding protein

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AKAP5 A kinase (PRKA) anchor protein 5
ARMC4 armadillo repeat containing 4
ASAP1-IT1 ASAP1 intronic transcript 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BEND5 BEN domain containing 5
BICC1 BicC family RNA binding protein 1
C11ORF80 chromosome 11 open reading frame 80
C17ORF53 chromosome 17 open reading frame 53
C22ORF46 chromosome 22 open reading frame 46
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC106 coiled-coil domain containing 106
CCDC132 coiled-coil domain containing 132
CCDC186 coiled-coil domain containing 186
CD79B CD79b molecule, immunoglobulin-associated beta
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN15 claudin 15
CPED1 cadherin-like and PC-esterase domain containing 1
CPZ carboxypeptidase Z
CRMP1 collapsin response mediator protein 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND2D DENN/MADD domain containing 2D
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DTX2 deltex 2, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS8 growth arrest-specific 8
GEMIN8 gem (nuclear organelle) associated protein 8
GK3P glycerol kinase 3 pseudogene
GPX2 glutathione peroxidase 2
GRPR gastrin-releasing peptide receptor
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIRA histone cell cycle regulator
HIST1H2AL histone cluster 1, H2al
HOXA6 homeobox A6
HSPA1L heat shock 70kDa protein 1-like
IL22 interleukin 22
ITPKA inositol-trisphosphate 3-kinase A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIAA1107 KIAA1107
LIG4 ligase IV, DNA, ATP-dependent
LINC00472 long intergenic non-protein coding RNA 472
LOC100127972 uncharacterized LOC100127972
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMRN2 multimerin 2
MRPS18C mitochondrial ribosomal protein S18C
NELL2 NEL-like 2 (chicken)
ODF2 outer dense fiber of sperm tails 2
PAQR5 progestin and adipoQ receptor family member V
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PGP phosphoglycolate phosphatase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODXL2 podocalyxin-like 2
PQLC2 PQ loop repeat containing 2
PRSS53 protease, serine, 53
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RANBP17 RAN binding protein 17
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SIRAL2 SIR2 antiphage like 2
SLC22A14 solute carrier family 22, member 14
SND1-IT1 SND1 intronic transcript 1
SPEG SPEG complex locus
TAOK1 TAO kinase 1
TIGD6 tigger transposable element derived 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM206 transmembrane protein 206
TOM1 target of myb1 (chicken)
TPCN1 two pore segment channel 1
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
TSPAN32 tetraspanin 32
TSPAN8 tetraspanin 8
TUBA4B tubulin, alpha 4b
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF41 zinc finger protein 41
ZNF573 zinc finger protein 573