| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the bendroflumethiazide-3840 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADCK2 | aarF domain containing kinase 2 |
| ADCK4 | aarF domain containing kinase 4 |
| ADORA1 | adenosine A1 receptor |
| ADRA2B | adrenoceptor alpha 2B |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AIM2 | absent in melanoma 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARG1 | arginase 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD101 | CD101 molecule |
| CD200 | CD200 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CFHR4 | complement factor H-related 4 |
| CLSTN3 | calsyntenin 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| COL10A1 | collagen, type X, alpha 1 |
| CPNE7 | copine VII |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMWD | dystrophia myotonica, WD repeat containing |
| DTNB | dystrobrevin, beta |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EMX1 | empty spiracles homeobox 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FLJ11292 | |
| FOXO4 | forkhead box O4 |
| FRMD8 | FERM domain containing 8 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTPBP1 | GTP binding protein 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRS2 | insulin receptor substrate 2 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KIAA0319 | KIAA0319 |
| KIF1C | kinesin family member 1C |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MEGF6 | multiple EGF-like-domains 6 |
| MEGF8 | multiple EGF-like-domains 8 |
| MYLK | myosin light chain kinase |
| NOX1 | NADPH oxidase 1 |
| NUP188 | nucleoporin 188kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OMG | oligodendrocyte myelin glycoprotein |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PHF3 | PHD finger protein 3 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLXNB3 | plexin B3 |
| POM121 | POM121 transmembrane nucleoporin |
| POPDC3 | popeye domain containing 3 |
| PTCH1 | patched 1 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RBM34 | RNA binding motif protein 34 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2D3A | SH2 domain containing 3A |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SP1 | Sp1 transcription factor |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STAT4 | signal transducer and activator of transcription 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM40 | transmembrane protein 40 |
| TPSG1 | tryptase gamma 1 |
| TSGA10 | testis specific, 10 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC12 | tetratricopeptide repeat domain 12 |
| UBXN1 | UBX domain protein 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WTAP | Wilms tumor 1 associated protein |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF223 | zinc finger protein 223 |
| ZNF324 | zinc finger protein 324 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMH | anti-Mullerian hormone |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ARRB1 | arrestin, beta 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C4BPA | complement component 4 binding protein, alpha |
| CALML5 | calmodulin-like 5 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD80 | CD80 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHM | choroideremia (Rab escort protein 1) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CSAD | cysteine sulfinic acid decarboxylase |
| DAPK3 | death-associated protein kinase 3 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DSCAM | Down syndrome cell adhesion molecule |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMID1 | EMI domain containing 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FAM204A | family with sequence similarity 204, member A |
| FGF4 | fibroblast growth factor 4 |
| FUZ | fuzzy planar cell polarity protein |
| GLB1L | galactosidase, beta 1-like |
| GMPR | guanosine monophosphate reductase |
| GPATCH3 | G patch domain containing 3 |
| GPR143 | G protein-coupled receptor 143 |
| GPR19 | G protein-coupled receptor 19 |
| GPR21 | G protein-coupled receptor 21 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GTF2I | general transcription factor IIi |
| HDAC5 | histone deacetylase 5 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4E | histone cluster 1, H4e |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIAA1107 | KIAA1107 |
| LHX1 | LIM homeobox 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MED9 | mediator complex subunit 9 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCP1 | mature T-cell proliferation 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| OVOL1 | ovo-like zinc finger 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDH17 | protocadherin 17 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PMEL | premelanosome protein |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RGS2 | regulator of G-protein signaling 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STRA6 | stimulated by retinoic acid 6 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TONSL | tonsoku-like, DNA repair protein |
| TRAF4 | TNF receptor-associated factor 4 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM21 | tripartite motif containing 21 |
| TRIM25 | tripartite motif containing 25 |
| TWISTNB | TWIST neighbor |
| UBQLN4 | ubiquilin 4 |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR4 | WD repeat domain 4 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF41 | zinc finger protein 41 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
